ASH1L haploinsufficiency results in autistic-like phenotypes in mice and links Eph receptor gene to autism spectrum disorder

Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

(2020) F. Kyle Satterstrom et al.   CELL

EphA7 isoforms differentially regulate cortical dendrite development

(2020) Carrie E. Leonard et al.   PLoS One

Getting to the Cores of Autism

(2019) Lilia M. Iakoucheva et al.   CELL

SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring

(2019) Alessandro Sessa et al.   NEURON

Do Astrocytes Play a Role in Intellectual Disabilities?

(2019) Noémie Cresto et al.   TRENDS IN NEUROSCIENCES

Mutations in ASH1L confer susceptibility to Tourette syndrome

(2019) Shiguo Liu et al.   MOLECULAR PSYCHIATRY

Third-generationin situhybridization chain reaction: multiplexed, quantitative, sensitive, versatile, robust

(2018) Harry M. T. Choi et al.   DEVELOPMENT

Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition

(2018) Luye Qin et al.   NATURE NEUROSCIENCE

Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors

(2018) Tommaso Patriarchi et al.   SCIENCE

High-Throughput Automatic Training System for Odor-Based Learned Behaviors in Head-Fixed Mice

(2018) Zhe Han et al.   Frontiers in Neural Circuits

Synaptic dysfunction in complex psychiatric disorders: from genetics to mechanisms

(2018) Xinyuan Wang et al.   Genome Medicine

Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain

(2018) Arpiar Saunders et al.   CELL

EphA5 and EphA7 forward signaling enhances human hematopoietic stem and progenitor cell maintenance, migration, and adhesion via Rac1 activation

(2017) Thao M. Nguyen et al.   EXPERIMENTAL HEMATOLOGY

Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases

(2017) Holly A F Stessman et al.   NATURE GENETICS

Activity-induced histone modifications govern Neurexin-1 mRNA splicing and memory preservation

(2017) Xinlu Ding et al.   NATURE NEUROSCIENCE

Errant gardeners: glial-cell-dependent synaptic pruning and neurodevelopmental disorders

(2017) Urte Neniskyte et al.   NATURE REVIEWS NEUROSCIENCE

Synaptic Plasticity, Metaplasticity and Depression

(2016) Linnea Vose et al.   Current Neuropharmacology

Speech Discrimination Difficulties in High-Functioning Autism Spectrum Disorder Are Likely Independent of Auditory Hypersensitivity

(2016) William A. Dunlop et al.   Frontiers in Human Neuroscience

CHD8 haploinsufficiency results in autistic-like phenotypes in mice

(2016) Yuta Katayama et al.   NATURE

Selective synaptic remodeling of amygdalocortical connections associated with fear memory

(2016) Yang Yang et al.   NATURE NEUROSCIENCE

Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

(2016) Omer Durak et al.   NATURE NEUROSCIENCE

Receptor tyrosine kinase EphA7 is required for interneuron connectivity at specific subcellular compartments of granule cells

(2016) Simone Beuter et al.   Scientific Reports

Histone methyltransferase Ash1L mediates activity-dependent repression of neurexin-1α

(2016) Τao Zhu et al.   Scientific Reports

Repetitive grooming and sensorimotor abnormalities in an ephrin-A knockout model for Autism Spectrum Disorders

(2015) Rachel Wurzman et al.   BEHAVIOURAL BRAIN RESEARCH

Long-term stability of axonal boutons in the mouse barrel cortex

(2015) Qian Qiao et al.   Developmental Neurobiology

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

Excess of rare, inherited truncating mutations in autism

(2015) Niklas Krumm et al.   NATURE GENETICS

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Emotion and Decision Making: Multiple Modulatory Neural Circuits

(2014) Elizabeth A. Phelps et al.   Annual Review of Neuroscience

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia

(2014) B. Xu et al.   BLOOD

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior

(2014) Yang Zhan et al.   NATURE NEUROSCIENCE

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

Transcriptional and epigenetic regulation of Hebbian and non-Hebbian plasticity

(2014) Mikael C. Guzman-Karlsson et al.   NEUROPHARMACOLOGY

The trithorax group proteins Kismet and ASH1 promote H3K36 dimethylation to counteract Polycomb group repression in Drosophila

(2013) K. M. Dorighi et al.   DEVELOPMENT

Permanent Genetic Access to Transiently Active Neurons via TRAP: Targeted Recombination in Active Populations

(2013) Casey J. Guenthner et al.   NEURON

Polysialylated NCAM and EphrinA/EphA Regulate Synaptic Development of GABAergic Interneurons in Prefrontal Cortex

(2012) Leann H. Brennaman et al.   CEREBRAL CORTEX

Diagnostic Exome Sequencing in Persons with Severe Intellectual Disability

(2012) Joep de Ligt et al.   NEW ENGLAND JOURNAL OF MEDICINE

H3K36 Methylation Antagonizes PRC2-mediated H3K27 Methylation

(2011) Wen Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes

(2010) Jerzy Wegiel et al.   ACTA NEUROPATHOLOGICA

Tsc2-Rheb signaling regulates EphA-mediated axon guidance

(2010) Duyu Nie et al.   NATURE NEUROSCIENCE

Essential Role of the Histone Methyltransferase G9a in Cocaine-Induced Plasticity

(2010) I. Maze et al.   SCIENCE

DEGseq: an R package for identifying differentially expressed genes from RNA-seq data

(2009) Likun Wang et al.   BIOINFORMATICS

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

(2009) Jeffrey J. Hutsler et al.   BRAIN RESEARCH

CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing

(2009) F. Tie et al.   DEVELOPMENT

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Effects of the histone deacetylase inhibitor sodium butyrate in models of depression and anxiety

(2009) Brigitta B. Gundersen et al.   NEUROPHARMACOLOGY

Signaling Mechanisms Linking Neuronal Activity to Gene Expression and Plasticity of the Nervous System

(2008) Steven W. Flavell et al.   Annual Review of Neuroscience

Critical role of the 65-kDa isoform of glutamic acid decarboxylase in consolidation and generalization of Pavlovian fear memory

(2008) J. R. Bergado-Acosta et al.   LEARNING & MEMORY

Bidirectional modulation of synaptic functions by Eph/ephrin signaling

(2008) Rüdiger Klein   NATURE NEUROSCIENCE