Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking
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Title
Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking
Authors
Keywords
Parkinson's disease, alpha-synuclein, ER stress, beta-glucocerebrosidase, protein aggregation, iPSC-derived midbrain dopaminergic neurons, lysosomal dysfunction
Journal
NEURON
Volume 110, Issue 3, Pages 436-451.e11
Publisher
Elsevier BV
Online
2021-11-17
DOI
10.1016/j.neuron.2021.10.032
References
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