Assessing Colonic Exposure, Safety, and Clinical Activity of SRT2104, a Novel Oral SIRT1 Activator, in Patients with Mild to Moderate Ulcerative Colitis
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Assessing Colonic Exposure, Safety, and Clinical Activity of SRT2104, a Novel Oral SIRT1 Activator, in Patients with Mild to Moderate Ulcerative Colitis
Authors
Keywords
-
Journal
INFLAMMATORY BOWEL DISEASES
Volume 22, Issue 3, Pages 607-614
Publisher
Oxford University Press (OUP)
Online
2015-11-21
DOI
10.1097/mib.0000000000000597
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Resveratrol, an activator of SIRT1, upregulates AMPK and improves cardiac function in heart failure
- (2014) X.S. Gu et al. GENETICS AND MOLECULAR RESEARCH
- Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats
- (2013) Wen Yu et al. ASIAN JOURNAL OF ANDROLOGY
- Neuroprotective effect of resveratrol prophylaxis on experimental retinal ischemic injury
- (2013) Anita P. Vin et al. EXPERIMENTAL EYE RESEARCH
- Human Clinical Research and Therapeutics
- (2013) JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis
- (2013) Brian G. Feagan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pharmacokinetics and tolerability of SRT2104, a first-in-class small molecule activator of SIRT1, after single and repeated oral administration in man
- (2012) Ethan Hoffmann et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Resveratrol Mitigates Rat Retinal Ischemic Injury: The Roles of Matrix Metalloproteinase-9, Inducible Nitric Oxide, and Heme Oxygenase-1
- (2012) Xiao-Qian Liu et al. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
- Utility of faecal calprotectin analysis in adult inflammatory bowel disease
- (2012) Lyn A Smith WORLD JOURNAL OF GASTROENTEROLOGY
- Resveratrol Pretreatment Attenuates Cerebral Ischemic Injury by Upregulating Expression of Transcription Factor Nrf2 and HO-1 in Rats
- (2011) Junwei Ren et al. NEUROCHEMICAL RESEARCH
- Reduction of blood cholesterol and ischemic injury in the hypercholesteromic rabbits with modified resveratrol, logevinex
- (2010) Bela Juhaz et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Neuroprotective effects of resveratrol on ischemic injury mediated by improving brain energy metabolism and alleviating oxidative stress in rats
- (2010) Hua Li et al. NEUROPHARMACOLOGY
- Antidiabetic activity of resveratrol, a known SIRT1 activator in a genetic model for type-2 diabetes
- (2010) Sameer Sharma et al. PHYTOTHERAPY RESEARCH
- SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity
- (2009) Takeshi Yoshizaki et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
- (2009) Jesse J Smith et al. BMC Systems Biology
- The scientific basis of caloric restriction leading to longer life
- (2009) Luigi Fontana CURRENT OPINION IN GASTROENTEROLOGY
- Neuroprotective effects of resveratrol on ischemic injury mediated by modulating the release of neurotransmitter and neuromodulator in rats
- (2009) Chao Li et al. NEUROCHEMISTRY INTERNATIONAL
- Use of the noninvasive components of the mayo score to assess clinical response in Ulcerative Colitis
- (2008) James D. Lewis et al. INFLAMMATORY BOWEL DISEASES
- The role of exercise and PGC1α in inflammation and chronic disease
- (2008) Christoph Handschin et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now