Assessing Colonic Exposure, Safety, and Clinical Activity of SRT2104, a Novel Oral SIRT1 Activator, in Patients with Mild to Moderate Ulcerative Colitis

Resveratrol, an activator of SIRT1, upregulates AMPK and improves cardiac function in heart failure

(2014) X.S. Gu et al.   GENETICS AND MOLECULAR RESEARCH

Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats

(2013) Wen Yu et al.   ASIAN JOURNAL OF ANDROLOGY

Neuroprotective effect of resveratrol prophylaxis on experimental retinal ischemic injury

(2013) Anita P. Vin et al.   EXPERIMENTAL EYE RESEARCH

Human Clinical Research and Therapeutics

(2013)   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis

(2013) Brian G. Feagan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacokinetics and tolerability of SRT2104, a first-in-class small molecule activator of SIRT1, after single and repeated oral administration in man

(2012) Ethan Hoffmann et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Resveratrol Mitigates Rat Retinal Ischemic Injury: The Roles of Matrix Metalloproteinase-9, Inducible Nitric Oxide, and Heme Oxygenase-1

(2012) Xiao-Qian Liu et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Utility of faecal calprotectin analysis in adult inflammatory bowel disease

(2012) Lyn A Smith   WORLD JOURNAL OF GASTROENTEROLOGY

Resveratrol Pretreatment Attenuates Cerebral Ischemic Injury by Upregulating Expression of Transcription Factor Nrf2 and HO-1 in Rats

(2011) Junwei Ren et al.   NEUROCHEMICAL RESEARCH

Reduction of blood cholesterol and ischemic injury in the hypercholesteromic rabbits with modified resveratrol, logevinex

(2010) Bela Juhaz et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Neuroprotective effects of resveratrol on ischemic injury mediated by improving brain energy metabolism and alleviating oxidative stress in rats

(2010) Hua Li et al.   NEUROPHARMACOLOGY

Antidiabetic activity of resveratrol, a known SIRT1 activator in a genetic model for type-2 diabetes

(2010) Sameer Sharma et al.   PHYTOTHERAPY RESEARCH

SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity

(2009) Takeshi Yoshizaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo

(2009) Jesse J Smith et al.   BMC Systems Biology

The scientific basis of caloric restriction leading to longer life

(2009) Luigi Fontana   CURRENT OPINION IN GASTROENTEROLOGY

Neuroprotective effects of resveratrol on ischemic injury mediated by modulating the release of neurotransmitter and neuromodulator in rats

(2009) Chao Li et al.   NEUROCHEMISTRY INTERNATIONAL

Use of the noninvasive components of the mayo score to assess clinical response in Ulcerative Colitis

(2008) James D. Lewis et al.   INFLAMMATORY BOWEL DISEASES

The role of exercise and PGC1α in inflammation and chronic disease

(2008) Christoph Handschin et al.   NATURE