Defining genome-wide CRISPR–Cas genome-editing nuclease activity with GUIDE-seq
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Defining genome-wide CRISPR–Cas genome-editing nuclease activity with GUIDE-seq
Authors
Keywords
-
Journal
Nature Protocols
Volume 16, Issue 12, Pages 5592-5615
Publisher
Springer Science and Business Media LLC
Online
2021-11-13
DOI
10.1038/s41596-021-00626-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Highly Parallel Profiling of Cas9 Variant Specificity
- (2020) Jonathan L. Schmid-Burgk et al. MOLECULAR CELL
- Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants
- (2020) Russell T. Walton et al. SCIENCE
- CHANGE-seq reveals genetic and epigenetic effects on CRISPR–Cas9 genome-wide activity
- (2020) Cicera R. Lazzarotto et al. NATURE BIOTECHNOLOGY
- CRISPResso2 provides accurate and rapid genome editing sequence analysis
- (2019) Kendell Clement et al. NATURE BIOTECHNOLOGY
- Enhancing gene editing specificity by attenuating DNA cleavage kinetics
- (2019) Jeffrey C. Miller et al. NATURE BIOTECHNOLOGY
- Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol
- (2018) Lili Wang et al. NATURE BIOTECHNOLOGY
- CRISPR off-target analysis in genetically engineered rats and mice
- (2018) Keith R. Anderson et al. NATURE METHODS
- CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets
- (2017) Shengdar Q Tsai et al. NATURE METHODS
- BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks
- (2017) Winston X. Yan et al. Nature Communications
- Genome-editing Technologies for Gene and Cell Therapy
- (2016) Morgan L Maeder et al. MOLECULAR THERAPY
- Open-source guideseq software for analysis of GUIDE-seq data
- (2016) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells
- (2016) Benjamin P Kleinstiver et al. NATURE BIOTECHNOLOGY
- Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
- (2015) Ayal Hendel et al. NATURE BIOTECHNOLOGY
- Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors
- (2015) Xiaoling Wang et al. NATURE BIOTECHNOLOGY
- Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
- (2015) Daesik Kim et al. NATURE METHODS
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Anchored multiplex PCR for targeted next-generation sequencing
- (2014) Zongli Zheng et al. NATURE MEDICINE
- RNA-Guided Genome Editing in Plants Using a CRISPR–Cas System
- (2013) Kabin Xie et al. Molecular Plant
- Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing
- (2013) Nicola Crosetto et al. NATURE METHODS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now