More autopsy studies are needed to understand the pathogenesis of severe COVID-19

Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial

(2021) Renato D Lopes et al.   LANCET

Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity

(2021) L. Vanderbeke et al.   Nature Communications

Multi-dimensional and longitudinal systems profiling reveals predictive pattern of severe COVID-19

(2021) Marcel S. Woo et al.   iScience

Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19

(2021) Sarthak Sinha et al.   NATURE MEDICINE

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

(2021) Jan Wenzel et al.   NATURE NEUROSCIENCE

Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19

(2021) Felice D’Agnillo et al.   Science Translational Medicine

Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study

(2020) George Goshua et al.   Lancet Haematology

Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19

(2020) Yapeng Su et al.   CELL

Lung transplantation for patients with severe COVID-19

(2020) Ankit Bharat et al.   Science Translational Medicine