Repurposing an adenine riboswitch into a fluorogenic imaging and sensing tag

Super-resolution RNA imaging using a rhodamine-binding aptamer with fast exchange kinetics

(2021) Murat Sunbul et al.   NATURE BIOTECHNOLOGY

Signaling Aptamer Optimization through Selection Using RNA-Capturing Microsphere Particles

(2020) Tamaki Endoh et al.   ANALYTICAL CHEMISTRY

Imaging Intracellular S-Adenosyl Methionine Dynamics in Live Mammalian Cells with a Genetically Encoded Red Fluorescent RNA-Based Sensor

(2020) Xing Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intracellular Imaging with Genetically Encoded RNA-based Molecular Sensors

(2019) Zhining Sun et al.   Nanomaterials

Highly efficient expression of circular RNA aptamers in cells using autocatalytic transcripts

(2019) Jacob L. Litke et al.   NATURE BIOTECHNOLOGY

From fluorescent proteins to fluorogenic RNAs: Tools for imaging cellular macromolecules

(2019) Lynda Truong et al.   PROTEIN SCIENCE

Genetically Encoded Ratiometric RNA-Based Sensors for Quantitative Imaging of Small Molecules in Living Cells

(2019) Rigumula Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorophore-Promoted RNA Folding and Photostability Enables Imaging of Single Broccoli-Tagged mRNAs in Live Mammalian Cells

(2019) Xing Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

SRB-2: a promiscuous rainbow aptamer for live-cell RNA imaging

(2018) Murat Sunbul et al.   NUCLEIC ACIDS RESEARCH

Strategies for designing non-natural enzymes and binders

(2018) Horst Lechner et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A Multicolor Large Stokes Shift Fluorogen-Activating RNA Aptamer with Cationic Chromophores

(2018) Christian Steinmetzger et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors

(2017) Ely B Porter et al.   Nature Chemical Biology

Imaging RNA polymerase III transcription using a photostable RNA–fluorophore complex

(2017) Wenjiao Song et al.   Nature Chemical Biology

Metabolic control of methylation and acetylation

(2016) Xiaoyang Su et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism

(2015) Samantha J. Mentch et al.   Cell Metabolism

In-Gel Imaging of RNA Processing Using Broccoli Reveals Optimal Aptamer Expression Strategies

(2015) Grigory S. Filonov et al.   CHEMISTRY & BIOLOGY

Broccoli: Rapid Selection of an RNA Mimic of Green Fluorescent Protein by Fluorescence-Based Selection and Directed Evolution

(2014) Grigory S. Filonov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Plug-and-Play Fluorophores Extend the Spectral Properties of Spinach

(2014) Wenjiao Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells

(2014) Bryce W. Carey et al.   NATURE

Engineering Genetically Encoded FRET Sensors

(2014) Laurens Lindenburg et al.   SENSORS

The Cellular Environment Stabilizes Adenine Riboswitch RNA Structure

(2013) Jillian Tyrrell et al.   BIOCHEMISTRY

Biallelic Expression of Nanog Protein in Mouse Embryonic Stem Cells

(2013) Adam Filipczyk et al.   Cell Stem Cell

Understanding the Photophysics of the Spinach–DFHBI RNA Aptamer–Fluorogen Complex To Improve Live-Cell RNA Imaging

(2013) Kyu Young Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RNA-Based Fluorescent Biosensors for Live Cell Imaging of Second Messengers Cyclic di-GMP and Cyclic AMP-GMP

(2013) Colleen A. Kellenberger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat–containing RNA

(2013) Rita L Strack et al.   NATURE METHODS

Single-molecule chemical denaturation of riboswitches

(2013) Paul A. Dalgarno et al.   NUCLEIC ACIDS RESEARCH

Programmable folding of fusion RNA in vivo and in vitro driven by pRNA 3WJ motif of phi29 DNA packaging motor

(2013) Dan Shu et al.   NUCLEIC ACIDS RESEARCH

Selection of RNAs for Constructing “Lighting-UP” Biomolecular Switches in Response to Specific Small Molecules

(2013) Tamaki Endoh et al.   PLoS One

Direct Observation of Cotranscriptional Folding in an Adenine Riboswitch

(2012) K. L. Frieda et al.   SCIENCE

Fluorescence Imaging of Cellular Metabolites with RNA

(2012) Jeremy S. Paige et al.   SCIENCE

Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation

(2012) N. Shyh-Chang et al.   SCIENCE

RNA Mimics of Green Fluorescent Protein

(2011) J. S. Paige et al.   SCIENCE

Design and application of genetically encoded biosensors

(2011) Amy E. Palmer et al.   TRENDS IN BIOTECHNOLOGY

Comparative Study between Transcriptionally- and Translationally-Acting Adenine Riboswitches Reveals Key Differences in Riboswitch Regulatory Mechanisms

(2011) Jean-François Lemay et al.   PLoS Genetics

Reengineering orthogonally selective riboswitches

(2010) N. Dixon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dependence of Mouse Embryonic Stem Cells on Threonine Catabolism

(2009) Jian Wang et al.   SCIENCE

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

Crystal structures of the SAM-III/SMK riboswitch reveal the SAM-dependent translation inhibition mechanism

(2008) Changrui Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY