Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression
出版年份 2022 全文链接
标题
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression
作者
关键词
-
出版物
NATURE CELL BIOLOGY
Volume 24, Issue 2, Pages 230-241
出版商
Springer Science and Business Media LLC
发表日期
2022-02-11
DOI
10.1038/s41556-021-00820-9
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity
- (2021) Baihao Zhang et al. NATURE
- The GABAB Receptor—Structure, Ligand Binding and Drug Development
- (2020) Linn Samira Mari Evenseth et al. MOLECULES
- GABRP regulates chemokine signalling, macrophage recruitment and tumour progression in pancreatic cancer through tuning KCNN4-mediated Ca2+ signalling in a GABA-independent manner
- (2019) Shu-Heng Jiang et al. GUT
- Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors
- (2019) Denarda Dangaj et al. CANCER CELL
- β-Catenin Activation Promotes Immune Escape and Resistance to Anti–PD-1 Therapy in Hepatocellular Carcinoma
- (2019) Marina Ruiz de Galarreta et al. Cancer Discovery
- Neurotransmitters: emerging targets in cancer
- (2019) Shu-Heng Jiang et al. ONCOGENE
- Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy
- (2019) John-Michael Williford et al. Science Advances
- Capillary morphogenesis protein 2 is a novel prognostic biomarker and plays oncogenic roles in glioma
- (2018) Juan Tan et al. JOURNAL OF PATHOLOGY
- The stress response gene ATF3 is a direct target of the Wnt/β-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells
- (2018) Makoto Inoue et al. PLoS One
- GABA B R-Induced EGFR Transactivation Promotes Migration of Human Prostate Cancer Cells
- (2017) Shuai Xia et al. MOLECULAR PHARMACOLOGY
- GABA Type A Receptor Activation in the Allosteric Coagonist Model Framework: Relationship between EC50and Basal Activity
- (2017) Gustav Akk et al. MOLECULAR PHARMACOLOGY
- Critical Role for CD103 + /CD141 + Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma
- (2016) Edward W. Roberts et al. CANCER CELL
- Expansion and Activation of CD103 + Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition
- (2016) Hélène Salmon et al. IMMUNITY
- Wnt signaling in cancer
- (2016) T Zhan et al. ONCOGENE
- The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis
- (2016) Kiranmai Gumireddy et al. Nature Communications
- Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
- (2015) Stefani Spranger et al. NATURE
- Targeting miR-23a in CD8+ cytotoxic T lymphocytes prevents tumor-dependent immunosuppression
- (2014) Regina Lin et al. JOURNAL OF CLINICAL INVESTIGATION
- Mass-spectrometry-based draft of the human proteome
- (2014) Mathias Wilhelm et al. NATURE
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- Systematic identification of signaling pathways with potential to confer anticancer drug resistance
- (2014) C. A. Martz et al. Science Signaling
- Glutamine and cancer: cell biology, physiology, and clinical opportunities
- (2013) Christopher T. Hensley et al. JOURNAL OF CLINICAL INVESTIGATION
- Different Subtypes of GABA-A Receptors Are Expressed in Human, Mouse and Rat T Lymphocytes
- (2012) Suresh K. Mendu et al. PLoS One
- Lentiviral Vectors to Probe and Manipulate the Wnt Signaling Pathway
- (2010) Christophe Fuerer et al. PLoS One
- Inhibitory role for GABA in autoimmune inflammation
- (2010) R. Bhat et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glutamine addiction: a new therapeutic target in cancer
- (2010) David R. Wise et al. TRENDS IN BIOCHEMICAL SCIENCES
- GABA’s Control of Stem and Cancer Cell Proliferation in Adult Neural and Peripheral Niches
- (2009) Stephanie Z. Young et al. PHYSIOLOGY
- GABA, a natural immunomodulator of T lymphocytes
- (2008) Helen Bjurstöm et al. JOURNAL OF NEUROIMMUNOLOGY
- Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity
- (2008) K. Hildner et al. SCIENCE
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