Anatomically distinct fibroblast subsets determine skin autoimmune patterns

Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses

(2021) Jennifer A. Lo et al.   Science Translational Medicine

scRNA-seq of human vitiligo reveals complex networks of subclinical immune activation and a role for CCR5 in T reg function

(2021) Kyle J. Gellatly et al.   Science Translational Medicine

Vitiligo: Mechanisms of Pathogenesis and Treatment

(2020) Michael L. Frisoli et al.   Annual Review of Immunology

The impact of NBUVB on microbial community profiling in the lesional skin of vitiligo subjects

(2020) Xiangfeng Yuan et al.   MICROBIAL PATHOGENESIS

The Genetic Basis of Vitiligo

(2020) Richard A. Spritz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo

(2019) Meri K. Tulic et al.   Nature Communications

Vitiligo under anti-PD1 therapy is associated with increased survival in melanoma patients

(2019) Charlée Nardin et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Epithelial cells: liaisons of immunity

(2019) Samantha B Larsen et al.   CURRENT OPINION IN IMMUNOLOGY

Skin Cell Heterogeneity in Development, Wound Healing, and Cancer

(2018) Emanuel Rognoni et al.   TRENDS IN CELL BIOLOGY

Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration

(2018) Zhou Yu et al.   Cell Stem Cell

Resident memory and recirculating memory T cells cooperate to maintain disease in a mouse model of vitiligo

(2018) Jillian M. Richmond et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

CD49a Expression Defines Tissue-Resident CD8 + T Cells Poised for Cytotoxic Function in Human Skin

(2017) Stanley Cheuk et al.   IMMUNITY

Keratinocyte-Derived Chemokines Orchestrate T-Cell Positioning in the Epidermis during Vitiligo and May Serve as Biomarkers of Disease

(2017) Jillian M. Richmond et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Current and emerging treatments for vitiligo

(2017) Michelle Rodrigues et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Promoter Specificity and Efficacy in Conditional and Inducible Transgenic Targeting of Lung Macrophages

(2017) Alexandra L. McCubbrey et al.   Frontiers in Immunology

Vitiligo: Pathogenesis, clinical variants and treatment approaches

(2016) Giannicola Iannella et al.   AUTOIMMUNITY REVIEWS

Metastatic melanoma and immunotherapy

(2016) Benjamin Herzberg et al.   CLINICAL IMMUNOLOGY

Association of Vitiligo With Tumor Response in Patients With Metastatic Melanoma Treated With Pembrolizumab

(2016) Camille Hua et al.   JAMA Dermatology

Psoriasis

(2016) Jacqueline E. Greb et al.   Nature Reviews Disease Primers

Systemic lupus erythematosus

(2016) Arvind Kaul et al.   Nature Reviews Disease Primers

Microbial community profiling shows dysbiosis in the lesional skin of Vitiligo subjects

(2016) Parul Ganju et al.   Scientific Reports

Interferon-gamma Inhibits Melanogenesis and Induces Apoptosis in Melanocytes: A Pivotal Role of CD8+ Cytotoxic T Lymphocytes in Vitiligo

(2015) L Yang et al.   ACTA DERMATO-VENEREOLOGICA

Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations

(2015) Chih-Chiang Chen et al.   CELL

Psoriasis

(2015) Wolf-Henning Boehncke et al.   LANCET

Vitiligo

(2015) Khaled Ezzedine et al.   LANCET

Vitiligo

(2015) Mauro Picardo et al.   Nature Reviews Disease Primers

The role of neuropeptides in the control of regional immunity

(2014) Torello Lotti et al.   CLINICS IN DERMATOLOGY

Autoimmune Vitiligo Does Not Require the Ongoing Priming of Naive CD8 T Cells for Disease Progression or Associated Protection against Melanoma

(2014) K. T. Byrne et al.   JOURNAL OF IMMUNOLOGY

Interferon-γ Induces Senescence in Normal Human Melanocytes

(2014) Suiquan Wang et al.   PLoS One

Detection of self-reactive CD8+T cells with an anergic phenotype in healthy individuals

(2014) Yuka Maeda et al.   SCIENCE

CXCL10 Is Critical for the Progression and Maintenance of Depigmentation in a Mouse Model of Vitiligo

(2014) M. Rashighi et al.   Science Translational Medicine

A Quantitative Increase in Regulatory T Cells Controls Development of Vitiligo

(2013) Shilpak Chatterjee et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mutant HSP70 Reverses Autoimmune Depigmentation in Vitiligo

(2013) J. A. Mosenson et al.   Science Translational Medicine

Innate immune defense system of the skin

(2013) Maryam Afshar et al.   VETERINARY DERMATOLOGY

A Mouse Model of Vitiligo with Focused Epidermal Depigmentation Requires IFN-γ for Autoreactive CD8+ T-Cell Accumulation in the Skin

(2012) John E. Harris et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration

(2012) Ting Chen et al.   NATURE

CXCR3 in T cell function

(2011) Joanna R. Groom et al.   EXPERIMENTAL CELL RESEARCH

Vitiligo: A comprehensive overview

(2011) Ali Alikhan et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells

(2010) Yuefeng Tang et al.   GENESIS

Mechanisms of Spatial and Temporal Development of Autoimmune Vitiligo in Tyrosinase-Specific TCR Transgenic Mice

(2010) Randal K. Gregg et al.   JOURNAL OF IMMUNOLOGY

A Novel Mouse Model of Inflammatory Bowel Disease Links Mammalian Target of Rapamycin-Dependent Hyperproliferation of Colonic Epithelium to Inflammation-Associated Tumorigenesis

(2009) Lin Deng et al.   AMERICAN JOURNAL OF PATHOLOGY

Autoimmune Destruction of Skin Melanocytes by Perilesional T Cells from Vitiligo Patients

(2009) Jasper G. van den Boorn et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Vitiligo

(2009) Alain Taïeb et al.   NEW ENGLAND JOURNAL OF MEDICINE

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE