Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages

Immunomodulation of Tumor Microenvironment by Arginine-Loaded Iron Oxide Nanoparticles for Gaseous Immunotherapy

(2021) Xiaqing Wu et al.   ACS Applied Materials & Interfaces

Ironing Out the Details: How Iron Orchestrates Macrophage Polarization

(2021) Yaoyao Xia et al.   Frontiers in Immunology

The Use of Iron Oxide Nanoparticles to Reprogram Macrophage Responses and the Immunological Tumor Microenvironment

(2021) Vladimir Mulens-Arias et al.   Frontiers in Immunology

M2-like polarization of THP-1 monocyte-derived macrophages under chronic iron overload

(2020) Jun-Kai Kao et al.   ANNALS OF HEMATOLOGY

Overexpression of miR‐199/214 is a distinctive feature of iron‐induced and asbestos‐induced sarcomatoid mesothelioma in rats

(2020) Yasumasa Okazaki et al.   CANCER SCIENCE

Differently Charged Super-Paramagnetic Iron Oxide Nanoparticles Preferentially Induced M1-Like Phenotype of Macrophages

(2020) Wenyue Zhang et al.   Frontiers in Bioengineering and Biotechnology

The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications

(2020) Yuanyuan Zhang et al.   Cellular & Molecular Immunology

Anti‑CD206 antibody‑conjugated Fe3O4‑based PLGA nanoparticles selectively promote tumor‑associated macrophages to polarize to the pro‑inflammatory subtype

(2020) Yun Zhou et al.   Oncology Letters

Magnetic Iron Oxide Nanoparticle (IONP) Synthesis to Applications: Present and Future

(2020) Nene Ajinkya et al.   Materials

Metabolic programming of tumor associated macrophages in the context of cancer treatment

(2020) Thomas Crezee et al.   Annals of Translational Medicine

Therapeutic strategies of iron-based nanomaterials for cancer therapy

(2020) Xiaqing Wu et al.   Biomedical Materials

A critical review on quantum dots: From synthesis toward applications in electrochemical biosensors for determination of disease-related biomolecules

(2020) Mohammad Ali Farzin et al.   TALANTA

Iron as a Central Player and Promising Target in Cancer Progression

(2019) Michaela Jung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Simultaneous T Cell Activation and Macrophage Polarization to Promote Potent Tumor Suppression by Iron Oxide-Embedded Large-Pore Mesoporous Organosilica Core-Shell Nanospheres

(2019) Lin Chen et al.   Advanced Healthcare Materials

Artificially Reprogrammed Macrophages as Tumor-Tropic Immunosuppression-Resistant Biologics to Realize Therapeutics Production and Immune Activation

(2019) Chu-Xin Li et al.   ADVANCED MATERIALS

Iron oxide nanoparticles promote macrophage autophagy and inflammatory response through activation of toll-like Receptor-4 signaling

(2019) Rongrong Jin et al.   BIOMATERIALS

Iron‐load exacerbates the severity of atherosclerosis via inducing inflammation and enhancing the glycolysis in macrophages

(2019) Xiaorong Hu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tissue Iron Promotes Wound Repair via M2 Macrophage Polarization and the Chemokine (C-C Motif) Ligands 17 and 22

(2019) Holly N. Wilkinson et al.   AMERICAN JOURNAL OF PATHOLOGY

Metal Oxide Nanoparticles in Therapeutic Regulation of Macrophage Functions

(2019) Marina S. Dukhinova et al.   Nanomaterials

Iron chelated melanin-like nanoparticles for tumor-associated macrophage repolarization and cancer therapy

(2019) Lei Rong et al.   BIOMATERIALS

Engineered nano-immunopotentiators efficiently promote cancer immunotherapy for inhibiting and preventing lung metastasis of melanoma

(2019) Lijia Luo et al.   BIOMATERIALS

Preclinical Evaluation and Clinical Translation of Magnetite-Based Nanomedicines

(2019) Julia V. Nuzhina et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Current Strategies to Target Tumor-Associated-Macrophages to Improve Anti-Tumor Immune Responses

(2019) Anfray et al.   Cells

Cell iron status influences macrophage polarization

(2018) Rafiou Agoro et al.   PLoS One

Recent biomedical applications of gold nanoparticles: A review

(2018) Narges Elahi et al.   TALANTA

Iron overloaded polarizes macrophage to proinflammation phenotype through ROS/acetyl-p53 pathway

(2018) Yun Zhou et al.   Cancer Medicine

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

(2018) Christopher B. Rodell et al.   Nature Biomedical Engineering

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Diverse Functions of Macrophages in Different Tumor Microenvironments

(2018) Ming Yang et al.   CANCER RESEARCH

Iron oxide nanoparticles enhance Toll-like receptor-induced cytokines in a particle size- and actin-dependent manner in human blood

(2018) Susann Wolf-Grosse et al.   Nanomedicine

Impact of Morphology on Iron Oxide Nanoparticles-Induced Inflammasome Activation in Macrophages

(2018) Liu Liu et al.   ACS Applied Materials & Interfaces

The role of iron metabolism in cancer therapy focusing on tumor-associated macrophages

(2018) Dandan Dong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression

(2017) Yu Zhu et al.   IMMUNITY

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity

(2017) Sydney R. Gordon et al.   NATURE

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Nanoparticles: Properties, applications and toxicities

(2017) Ibrahim Khan et al.   Arabian Journal of Chemistry

The tumor microenvironment and inflammatory breast cancer

(2017) Aji Huang et al.   Journal of Cancer

Combination of CD40 Agonism and CSF-1R Blockade Reconditions Tumor-Associated Macrophages and Drives Potent Antitumor Immunity

(2017) Karla R. Wiehagen et al.   Cancer Immunology Research

Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages

(2017) Milene Costa da Silva et al.   Frontiers in Immunology

Iron Handling in Tumor-Associated Macrophages—Is There a New Role for Lipocalin-2?

(2017) Michaela Jung et al.   Frontiers in Immunology

Reprogramming of Tumor-Associated Macrophages with Anticancer Therapies: Radiotherapy versus Chemo- and Immunotherapies

(2017) Géraldine Genard et al.   Frontiers in Immunology

Macrophages and Iron Metabolism

(2016) Miguel P. Soares et al.   IMMUNITY

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

(2016) Saeid Zanganeh et al.   Nature Nanotechnology

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

(2016) Daniel Bobo et al.   PHARMACEUTICAL RESEARCH

Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression

(2016) Christina Mertens et al.   PLoS One

Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis

(2016) Anna-Maria Georgoudaki et al.   Cell Reports

An interferon-γ-delivery system based on chitosan/poly(γ-glutamic acid) polyelectrolyte complexes modulates macrophage-derived stimulation of cancer cell invasion in vitro

(2015) Ana P. Cardoso et al.   Acta Biomaterialia

An overview of molecular basis of iron metabolism regulation and the associated pathologies

(2015) Bruno Silva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Macrophage iron homeostasis and polarization in the context of cancer

(2015) Michaela Jung et al.   IMMUNOBIOLOGY

The interaction of anticancer therapies with tumor-associated macrophages

(2015) Alberto Mantovani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pulmonary Alveolar Macrophages Contribute to the Premetastatic Niche by Suppressing Antitumor T Cell Responses in the Lungs

(2015) Sharad K. Sharma et al.   JOURNAL OF IMMUNOLOGY

Cancer nanomedicine: addressing the dark side of the enhanced permeability and retention effect

(2015) Elizabeth Huynh et al.   Nanomedicine

Role of the Tumor Microenvironment in Breast Cancer

(2015) Savas D. Soysal et al.   PATHOBIOLOGY

Hepcidin and Host Defense against Infectious Diseases

(2015) Kathryn Michels et al.   PLoS Pathogens

The combination of a novel immunomodulator with a regulatory T cell suppressing antibody (DTA-1) regress advanced stage B16F10 solid tumor by repolarizing tumor associated macrophagesin situ

(2015) Sayantan Banerjee et al.   OncoImmunology

The Molecular Biology of Human Iron Metabolism

(2015) William E. Winter et al.   Labmedicine

Tracking of intertissue migration reveals the origins of tumor-infiltrating monocytes

(2014) F. H. W. Shand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SPION primes THP1 derived M2 macrophages towards M1-like macrophages

(2013) Amit Laskar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Orchestration of Metabolism by Macrophages

(2012) Subhra K. Biswas et al.   Cell Metabolism

Design of polymeric nanoparticles for biomedical delivery applications

(2012) Mahmoud Elsabahy et al.   CHEMICAL SOCIETY REVIEWS

Macrophages in Tumor Microenvironments and the Progression of Tumors

(2012) Ning-Bo Hao et al.   Clinical & Developmental Immunology

Chemical Design of Biocompatible Iron Oxide Nanoparticles for Medical Applications

(2012) Daishun Ling et al.   Small

Nanoparticle Delivery of Cancer Drugs

(2011) Andrew Z. Wang et al.   Annual Review of Medicine

Triple-Negative Breast Cancer: An Unmet Medical Need

(2011) C. A. Hudis et al.   ONCOLOGIST

Effects of DMSA-coated Fe3O4 magnetic nanoparticles on global gene expression of mouse macrophage RAW264.7 cells

(2011) Yingxun Liu et al.   TOXICOLOGY LETTERS

Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy

(2010) Morteza Mahmoudi et al.   ADVANCED DRUG DELIVERY REVIEWS

Toxicology of engineered nanomaterials: Focus on biocompatibility, biodistribution and biodegradation

(2010) Andrea Kunzmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Polarization dictates iron handling by inflammatory and alternatively activated macrophages

(2010) G. Corna et al.   HAEMATOLOGICA

Human Heme Oxygenase-1 Deficiency Presenting With Hemolysis, Nephritis, and Asplenia

(2010) Nita Radhakrishnan et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Regulatory T Cells: Major Players in the Tumor Microenvironment

(2009) Marc Beyer et al.   CURRENT PHARMACEUTICAL DESIGN

Differential regulation of iron homeostasis during human macrophage polarized activation

(2009) Stefania Recalcati et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interferon-γ reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages

(2009) Dorothée Duluc et al.   INTERNATIONAL JOURNAL OF CANCER

Effects of marginal iron overload on iron homeostasis and immune function in alveolar macrophages isolated from pregnant and normal rats

(2008) Roberta J. Ward et al.   BIOMETALS

Iron metabolism in the mononuclear phagocyte system

(2008) Weina Kong et al.   Progress in Natural Science-Materials International