Intercalation-Driven Formation of siRNA Nanogels for Cancer Therapy

The effector mechanism of siRNA spherical nucleic acids

(2020) Gokay Yamankurt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A programmable polymer library that enables the construction of stimuli-responsive nanocarriers containing logic gates

(2020) Penghui Zhang et al.   Nature Chemistry

siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice

(2020) Wei Tao et al.   Science Translational Medicine

Natural DNA Intercalators as Promising Therapeutics for Cancer and Infectious Diseases

(2019) Martyna Godzieba et al.   CURRENT CANCER DRUG TARGETS

Noncovalent tagging of siRNA with steroids for transmembrane delivery

(2018) Wanyi Tai et al.   BIOMATERIALS

DNA Nanostructure-Based Systems for Intelligent Delivery of Therapeutic Oligonucleotides

(2018) Qinqin Hu et al.   Advanced Healthcare Materials

A ribonucleoprotein octamer for targeted siRNA delivery

(2018) Wanyi Tai et al.   Nature Biomedical Engineering

PLK1, A Potential Target for Cancer Therapy

(2017) Zhixian Liu et al.   Translational Oncology

Intercalation-mediated nucleic acid nanoparticles for siRNA delivery

(2016) Kejin Zhou et al.   CHEMICAL COMMUNICATIONS

Enhanced protein internalization and efficient endosomal escape using polyampholyte-modified liposomes and freeze concentration

(2016) Sana Ahmed et al.   Nanoscale

In vivo toxicity of cationic micelles and liposomes

(2015) Kristina Bram Knudsen et al.   Nanomedicine-Nanotechnology Biology and Medicine

Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment

(2015) Xi Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multivalent Dendrimer Vectors with DNA Intercalation Motifs for Gene Delivery

(2014) Pamela T. Wong et al.   BIOMACROMOLECULES

PEGylated carboxymethyl chitosan/calcium phosphate hybrid anionic nanoparticles mediated hTERT siRNA delivery for anticancer therapy

(2014) Ying Xie et al.   BIOMATERIALS

The uptake mechanism of PEGylated DNA polyplexes by the liver influences gene expression

(2014) S Khargharia et al.   GENE THERAPY

PEG length and chemical linkage controls polyacridine peptide DNA polyplex pharmacokinetics, biodistribution, metabolic stability and in vivo gene expression

(2013) Sanjib Khargharia et al.   JOURNAL OF CONTROLLED RELEASE

High-affinity PEGylated polyacridine peptide polyplexes mediate potent in vivo gene expression

(2012) K Kizzire et al.   GENE THERAPY

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Current prospects for RNA interference-based therapies

(2011) Beverly L. Davidson et al.   NATURE REVIEWS GENETICS

Discovery of Metabolically Stabilized Electronegative Polyacridine-PEG Peptide DNA Open Polyplexes

(2010) Christian A. Fernandez et al.   BIOCONJUGATE CHEMISTRY

Metabolically stabilized long-circulating PEGylated polyacridine peptide polyplexes mediate hydrodynamically stimulated gene expression in liver

(2010) C A Fernandez et al.   GENE THERAPY

Synthesis and In Vitro Testing of New Potent Polyacridine−Melittin Gene Delivery Peptides

(2009) Nicholas J. Baumhover et al.   BIOCONJUGATE CHEMISTRY

Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles

(2009) Hae Yun Nam et al.   JOURNAL OF CONTROLLED RELEASE

On the Molecular Mechanism of Drug Intercalation into DNA: A Simulation Study of the Intercalation Pathway, Free Energy, and DNA Structural Changes

(2008) Arnab Mukherjee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY