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Title
Berberine as a Potential Anticancer Agent: A Comprehensive Review
Authors
Keywords
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Journal
MOLECULES
Volume 26, Issue 23, Pages 7368
Publisher
MDPI AG
Online
2021-12-06
DOI
10.3390/molecules26237368
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Note: Only part of the references are listed.- Therapeutic Strategies for Targeting IL-1 in Cancer
- (2021) Adrian Gottschlich et al. Cancers
- Berberine—A potent chemosensitizer and chemoprotector to conventional cancer therapies
- (2021) Nalini Devarajan et al. PHYTOTHERAPY RESEARCH
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- (2021) Yang Yang et al. EXPERIMENTAL CELL RESEARCH
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- (2020) Pengcheng Zhang et al. OncoTargets and Therapy
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- (2020) Ye Wang et al. OncoTargets and Therapy
- Berberine Inhibits MDA-MB-231 Cells by Attenuating Their Inflammatory Responses
- (2020) Lina Zhao et al. Biomed Research International
- Berberine represses human gastric cancer cell growth in vitro and in vivo by inducing cytostatic autophagy via inhibition of MAPK/mTOR/p70S6K and Akt signaling pathways
- (2020) Qiang Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
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- (2020) Elaheh Nasrollahzadeh et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
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- (2020) Jingjing Liu et al. JOURNAL OF PROTEOME RESEARCH
- Rapid determination and optimisation of berberine from Himalayan Berberis lycium by soxhlet apparatus using CCD-RSM and its quality control as a potential candidate for COVID-19
- (2020) Anil Kumar Katare et al. NATURAL PRODUCT RESEARCH
- Beta-Blockers and Berberine: A Possible Dual Approach to Contrast Neuroblastoma Growth and Progression
- (2020) Maura Calvani et al. Oxidative Medicine and Cellular Longevity
- Berberine Inhibits the Apoptosis-Induced Metastasis by Suppressing the iPLA2/LOX-5/LTB4 Pathway in Hepatocellular Carcinoma
- (2020) Yawei Zhao et al. OncoTargets and Therapy
- Low-Dose Berberine Attenuates the Anti-Breast Cancer Activity of Chemotherapeutic Agents via Induction of Autophagy and Antioxidation
- (2020) Bing Han et al. Dose-Response
- Optimizing extraction of berberine and antioxidant compounds from barberry by maceration and pulsed electric field-assisted methods
- (2020) Mozhdeh Sarraf et al. Journal of Berry Research
- The potential role of dietary plant ingredients against mammary cancer: a comprehensive review
- (2020) Amjad Hussain et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- Berberine Improves Chemo-Sensitivity to Cisplatin by Enhancing Cell Apoptosis and Repressing PI3K/AKT/mTOR Signaling Pathway in Gastric Cancer
- (2020) Yingying Kou et al. Frontiers in Pharmacology
- Berberine Promotes Apoptosis of Colorectal Cancer via Regulation of the Long Non-Coding RNA (lncRNA) Cancer Susceptibility Candidate 2 (CASC2)/AU-Binding Factor 1 (AUF1)/B-Cell CLL/Lymphoma 2 (Bcl-2) Axis
- (2019) Wei Dai et al. MEDICAL SCIENCE MONITOR
- Berberine as a potential autophagy modulator
- (2019) Reza Mohammadinejad et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Antitumor Effects of Berberine on Gliomas via Inactivation of Caspase-1-Mediated IL-1β and IL-18 Release
- (2019) Lei Tong et al. Frontiers in Oncology
- Ameliorative Effect of Berberine on Neonatally Induced Type 2 Diabetic Neuropathy via Modulation of BDNF, IGF-1, PPAR-γ, and AMPK Expressions
- (2019) Guangju Zhou et al. Dose-Response
- Different mechanisms involved in the berberine‐induced antiproliferation effects in triple‐negative breast cancer cell lines
- (2019) Yen‐Shu Lin et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Berberine inhibits NLRP3 Inflammasome pathway in human triple-negative breast cancer MDA-MB-231 cell
- (2019) Mingjiang Yao et al. BMC Complementary and Alternative Medicine
- Preventive and Therapeutic Roles of Berberine in Gastrointestinal Cancers
- (2019) Siwang Hu et al. Biomed Research International
- Berberine suppresses growth and metastasis of endometrial cancer cells via miR-101/COX-2
- (2018) Yu Wang et al. BIOMEDICINE & PHARMACOTHERAPY
- Environmental hormesis and its fundamental biological basis: Rewriting the history of toxicology
- (2018) Evgenios Agathokleous et al. ENVIRONMENTAL RESEARCH
- Regulation of Akt/FoxO3a/Skp2 Axis Is Critically Involved in Berberine-Induced Cell Cycle Arrest in Hepatocellular Carcinoma Cells
- (2018) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Berberine, a natural plant alkaloid, synergistically sensitizes human liver cancer cells to sorafenib
- (2018) Yuezhao Huang et al. ONCOLOGY REPORTS
- Coptidis rhizoma and its main bioactive components: recent advances in chemical investigation, quality evaluation and pharmacological activity
- (2018) Fan-Cheng Meng et al. Chinese Medicine
- Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, uPA, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro
- (2018) Jia-Fang Liu et al. MOLECULES
- Berberine: Botanical Occurrence, Traditional Uses, Extraction Methods, and Relevance in Cardiovascular, Metabolic, Hepatic, and Renal Disorders
- (2018) Maria A. Neag et al. Frontiers in Pharmacology
- Development and In Vitro Evaluation of Linear PEI-Shelled Heparin/Berberine Nanoparticles in Human Osteosarcoma U-2 OS Cells
- (2018) Hung-Kun Hsu et al. MOLECULES
- Berberine Attenuated Proliferation, Invasion and Migration by Targeting the AMPK/HNF4α/WNT5A Pathway in Gastric Carcinoma
- (2018) Qian Hu et al. Frontiers in Pharmacology
- IL-1 and IL-1 regulatory pathways in cancer progression and therapy
- (2017) Alberto Mantovani et al. IMMUNOLOGICAL REVIEWS
- Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors
- (2017) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Demonstration of a potent RET transcriptional inhibitor for the treatment of medullary thyroid carcinoma based on an ellipticine derivative
- (2017) Vishnu Muthuraj Kumarasamy et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Berberine displays antitumor activity in esophageal cancer cells in vitro
- (2017) Shu-Xian Jiang et al. WORLD JOURNAL OF GASTROENTEROLOGY
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- A General, Concise Strategy that Enables Collective Total Syntheses of over 50 Protoberberine and Five Aporhoeadane Alkaloids within Four to Eight Steps
- (2016) Shiqiang Zhou et al. CHEMISTRY-A EUROPEAN JOURNAL
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- (2016) Tobias S. Slørdahl et al. Oncotarget
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- (2016) Jiwei Wang et al. Oncotarget
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- Current knowledge and pharmacological profile of berberine: An update
- (2015) Anil Kumar et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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- (2015) Chia-Hung Liu et al. International Journal of Medical Sciences
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- (2015) Yongliang Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Berberine induces apoptosis by suppressing the arachidonic acid metabolic pathway in hepatocellular carcinoma
- (2015) JING LI et al. Molecular Medicine Reports
- Berberine and Curcumin Target Survivin and STAT3 in Gastric Cancer Cells and Synergize Actions of Standard Chemotherapeutic 5-Fluorouracil
- (2015) Arvind Pandey et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
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- (2015) JAE-SUNG KIM et al. ONCOLOGY REPORTS
- Systematic analysis of berberine-induced signaling pathway between miRNA clusters and mRNAs and identification of mir-99a∼125b cluster function by seed-targeting inhibitors in multiple myeloma cells
- (2015) Maoxiao Feng et al. RNA Biology
- Growth-suppressive effect of berberine on endometrial carcinoma cells: Role of mitochondrial and PI3K/Akt pathway
- (2015) Han-Peng Kuo et al. Journal of Functional Foods
- Transforming berberine into its intestine-absorbable form by the gut microbiota
- (2015) Ru Feng et al. Scientific Reports
- MicroRNA-21 and the clinical outcomes of various carcinomas: a systematic review and meta-analysis
- (2014) Wenjia Wang et al. BMC CANCER
- Integrative analysis of differential miRNA and functional study of miR-21 by seed-targeting inhibition in multiple myeloma cells in response to berberine
- (2014) Xiaochuang Luo et al. BMC Systems Biology
- Berberine induces apoptosis via ROS generation in PANC-1 and MIA-PaCa2 pancreatic cell lines
- (2014) S.H. Park et al. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
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- (2014) Qu Zhang et al. Diagnostic Pathology
- Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer
- (2014) Parham Jabbarzadeh Kaboli et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Berberine and Its Metabolites: Relationship between Physicochemical Properties and Plasma Levels after Administration to Human Subjects
- (2014) Silvia Spinozzi et al. JOURNAL OF NATURAL PRODUCTS
- Berberine diminishes side population and down-regulates stem cell-associated genes in the pancreatic cancer cell lines PANC-1 and MIA PaCa-2
- (2014) S. H. Park et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Berberine induces apoptosis and DNA damage in MG-63 human osteosarcoma cells
- (2014) YU ZHU et al. Molecular Medicine Reports
- Berberine, an Epiphany Against Cancer
- (2014) Luis Guamán Ortiz et al. MOLECULES
- Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells
- (2014) Ming Ming et al. PLoS One
- Evaluation of HPLC and spectrophotometric methods for analysis of bioactive constituent berberine in stem extracts ofCoscinium fenestratum
- (2013) G. A. Akowuah et al. ACTA CHROMATOGRAPHICA
- Effects of ultrahigh pressure extraction conditions on yields of berberine and palmatine from cortex Phellodendri amurensis
- (2013) Shun Liu et al. Analytical Methods
- Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts
- (2013) Chi Man Tsang et al. BMC CANCER
- Berberine Reduces the Metastasis of Chondrosarcoma by Modulating theαvβ3 Integrin and the PKCδ, c-Src, and AP-1 Signaling Pathways
- (2013) Chi-Ming Wu et al. Evidence-based Complementary and Alternative Medicine
- Berberine metabolites exhibit triglyceride-lowering effects via activation of AMP-activated protein kinase in Hep G2 cells
- (2013) Shijie Cao et al. JOURNAL OF ETHNOPHARMACOLOGY
- Excretion of Berberine and Its Metabolites in Oral Administration in Rats
- (2013) Jing‐Yi Ma et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Berberine induces selective apoptosis through the AMPK-mediated mitochondrial/caspase pathway in hepatocellular carcinoma
- (2013) XIAOLONG YANG et al. Molecular Medicine Reports
- Berberine in combination with doxorubicin suppresses growth of murine melanoma B16F10 cells in culture and xenograft
- (2013) Anil Mittal et al. PHYTOMEDICINE
- Tissue Distribution of Berberine and Its Metabolites after Oral Administration in Rats
- (2013) Xiang-Shan Tan et al. PLoS One
- Inhibition of organic cation transporter 2 and 3 may be involved in the mechanism of the antidepressant-like action of berberine
- (2013) Siyuan Sun et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Set9, NF-κB and microRNA-21 mediate berberine-induced apoptosis of human multiple myeloma cells
- (2012) Hai-yan Hu et al. ACTA PHARMACOLOGICA SINICA
- Berberine and its derivatives: a patent review (2009 – 2012)
- (2012) Inder Pal Singh et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Berberine Inhibited the Growth of Thyroid Cancer Cell Lines 8505C and TPC1
- (2012) Kyoung Sik Park et al. YONSEI MEDICAL JOURNAL
- Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression
- (2011) Hak-Su Kim et al. BIOCHEMICAL PHARMACOLOGY
- Global cancer statistics
- (2011) Ahmedin Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Berberine Suppresses Androgen Receptor Signaling in Prostate Cancer
- (2011) J. Li et al. MOLECULAR CANCER THERAPEUTICS
- Isoquinoline Alkaloid Biosynthesis is Regulated by a Unique bHLH-Type Transcription Factor in Coptis japonica
- (2011) Yasuyuki Yamada et al. PLANT AND CELL PHYSIOLOGY
- Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells
- (2010) Samir Attoub et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Berberine Inhibits Cell Growth and Mediates Caspase-Independent Cell Death in Human Pancreatic Cancer Cells
- (2010) Lina Pinto-Garcia et al. PLANTA MEDICA
- The effects of berberine on the magnitude of the acute inflammatory response induced by Escherichia coli lipopolysaccharide in broiler chickens
- (2009) Y. B. Shen et al. POULTRY SCIENCE
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