Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder

Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program

(2021) Murray B. Stein et al.   NATURE GENETICS

Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions

(2021) Daniel F. Levey et al.   NATURE NEUROSCIENCE

Polygenic Risk Scores Derived From Varying Definitions of Depression and Risk of Depression

(2021) Brittany L. Mitchell et al.   JAMA Psychiatry

Reproducible Genetic Risk Loci for Anxiety: Results From ∼200,000 Participants in the Million Veteran Program

(2020) Daniel F. Levey et al.   AMERICAN JOURNAL OF PSYCHIATRY

A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles

(2020) Nancy Y. A. Sey et al.   NATURE NEUROSCIENCE

A simple new approach to variable selection in regression, with application to genetic fine mapping

(2020) Gao Wang et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Low-dose IL-2 therapy compensates for metabolic shifts and reverses anxiety-like behavior in PD-1 deficiency-induced autoimmunity

(2020) Cui Lv et al.   Cellular & Molecular Immunology

The GTEx Consortium atlas of genetic regulatory effects across human tissues

(2020)   SCIENCE

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

(2019) David M. Howard et al.   NATURE NEUROSCIENCE

Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life

(2019) W. David Hill et al.   MOLECULAR PSYCHIATRY

Genetic Variants Associated With Anxiety and Stress-Related Disorders

(2019) Sandra M. Meier et al.   JAMA Psychiatry

Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans

(2019) Joel Gelernter et al.   NATURE NEUROSCIENCE

PRSice-2: Polygenic Risk Score software for biobank-scale data

(2019) Shing Wan Choi et al.   GigaScience

The “All of Us” Research Program

(2019)   NEW ENGLAND JOURNAL OF MEDICINE

A major role for common genetic variation in anxiety disorders

(2019) Kirstin L. Purves et al.   MOLECULAR PSYCHIATRY

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

(2019) Caroline M. Nievergelt et al.   Nature Communications

ShinyGO: a graphical gene-set enrichment tool for animals and plants

(2019) Steven Xijin Ge et al.   BIOINFORMATICS

Network Mechanisms of Clinical Response to Transcranial Magnetic Stimulation in Posttraumatic Stress Disorder and Major Depressive Disorder

(2018) Noah S. Philip et al.   BIOLOGICAL PSYCHIATRY

A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex

(2018) Suijuan Zhong et al.   NATURE

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Multi-trait analysis of genome-wide association summary statistics using MTAG

(2018) Patrick Turley et al.   NATURE GENETICS

Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States

(2018) Deborah S. Hasin et al.   JAMA Psychiatry

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Distinguishing genetic correlation from causation across 52 diseases and complex traits

(2018) Luke J. O’Connor et al.   NATURE GENETICS

Overview of the BioBank Japan Project: Study design and profile

(2017) Akiko Nagai et al.   JOURNAL OF EPIDEMIOLOGY

Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability

(2017) L E Duncan et al.   MOLECULAR PSYCHIATRY

Million Veteran Program: A mega-biobank to study genetic influences on health and disease

(2016) John Michael Gaziano et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Meta-analysis of genome-wide association studies of anxiety disorders

(2016) T Otowa et al.   MOLECULAR PSYCHIATRY

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent

(2016) Craig L Hyde et al.   NATURE GENETICS

The asthma-anxiety connection

(2016) Stefano R. Del Giacco et al.   RESPIRATORY MEDICINE

The Philadelphia Neurodevelopmental Cohort: constructing a deep phenotyping collaborative

(2015) Monica E. Calkins et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Post-traumatic stress disorder

(2015) Rachel Yehuda et al.   Nature Reviews Disease Primers

Regularization Paths for Generalized Linear Models via Coordinate Descent

(2015) Jerome Friedman et al.   Journal of Statistical Software

The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort

(2014) E B Robinson et al.   MOLECULAR PSYCHIATRY

Dorsolateral Prefrontal Cortex Activation During Emotional Anticipation and Neuropsychological Performance in Posttraumatic Stress Disorder

(2012) Carolyn B. Allard   ARCHIVES OF GENERAL PSYCHIATRY

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

The Patient Health Questionnaire Somatic, Anxiety, and Depressive Symptom Scales: a systematic review

(2010) Kurt Kroenke et al.   GENERAL HOSPITAL PSYCHIATRY