Balancing Solid-State Stability and Dissolution Performance of Lumefantrine Amorphous Solid Dispersions: The Role of Polymer Choice and Drug–Polymer Interactions

Drug Release and Nanodroplet Formation from Amorphous Solid Dispersions: Insight into the Roles of Drug Physicochemical Properties and Polymer Selection

(2021) Ruochen Yang et al.   MOLECULAR PHARMACEUTICS

22 factorial design-based biocompatible microneedle arrays containing artemether co-loaded with lumefantrine nanoparticles for transepidermal delivery

(2020) Sandip Pawar et al.   BIOMEDICAL MICRODEVICES

Congruent release of drug and polymer from amorphous solid dispersions: insights into the role of drug-polymer hydrogen bonding, surface crystallization and glass transition

(2020) Sugandha Saboo et al.   MOLECULAR PHARMACEUTICS

Evidence for Halogen Bonding in Amorphous Solid Dispersions

(2020) Chailu Que et al.   CRYSTAL GROWTH & DESIGN

Patterns of drug release as a function of drug loading from amorphous solid dispersions: A comparison of five different polymers.

(2020) Sugandha Saboo et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Insights into the Dissolution Mechanism of Ritonavir–Copovidone Amorphous Solid Dispersions: Importance of Congruent Release for Enhanced Performance

(2019) Anura S. Indulkar et al.   MOLECULAR PHARMACEUTICS

Congruent release of drug and polymer: A “sweet spot” in the dissolution of amorphous solid dispersions

(2019) Sugandha Saboo et al.   JOURNAL OF CONTROLLED RELEASE

Insights into the Dissolution Behavior of Ledipasvir–Copovidone Amorphous Solid Dispersions: Role of Drug Loading and Intermolecular Interactions

(2019) Chailu Que et al.   MOLECULAR PHARMACEUTICS

Surface area normalized dissolution to study differences in itraconazole-copovidone solid dispersions prepared by spray-drying and hot melt extrusion

(2018) Vivekanand Bhardwaj et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Mechanistic Study of Belinostat Oral Absorption From Spray-Dried Dispersions

(2018) Aaron Stewart et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

In-situ single pass intestinal permeability and pharmacokinetic study of developed Lumefantrine loaded solid lipid nanoparticles

(2017) Anuj Garg et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Extraordinary Long-Term-Stability in Kinetically Stabilized Amorphous Solid Dispersions of Fenofibrate

(2017) Frank Theil et al.   MOLECULAR PHARMACEUTICS

Impact of Drug-Rich Colloids of Itraconazole and HPMCAS on Membrane Flux in Vitro and Oral Bioavailability in Rats

(2017) Aaron M. Stewart et al.   MOLECULAR PHARMACEUTICS

Phase Behavior of Ritonavir Amorphous Solid Dispersions during Hydration and Dissolution

(2017) Hitesh S. Purohit et al.   PHARMACEUTICAL RESEARCH

Formulation design,in vitrocharacterizations and anti-malarial investigations of artemether and lumefantrine-entrapped solid lipid microparticles

(2016) Chinazom Agbo et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Acid-base interactions in amorphous solid dispersions of lumefantrine prepared by spray-drying and hot-melt extrusion using X-ray photoelectron spectroscopy

(2016) Yang Song et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Frozen in Time: Kinetically Stabilized Amorphous Solid Dispersions of Nifedipine Stable after a Quarter Century of Storage

(2016) Frank Theil et al.   MOLECULAR PHARMACEUTICS

Nanoscale Infrared, Thermal, and Mechanical Characterization of Telaprevir–Polymer Miscibility in Amorphous Solid Dispersions Prepared by Solvent Evaporation

(2016) Na Li et al.   MOLECULAR PHARMACEUTICS

Exploiting the Phenomenon of Liquid–Liquid Phase Separation for Enhanced and Sustained Membrane Transport of a Poorly Water-Soluble Drug

(2016) Anura S. Indulkar et al.   MOLECULAR PHARMACEUTICS

Initial Drug Dissolution from Amorphous Solid Dispersions Controlled by Polymer Dissolution and Drug-Polymer Interaction

(2016) Yuejie Chen et al.   PHARMACEUTICAL RESEARCH

Acid–Base Interactions of Polystyrene Sulfonic Acid in Amorphous Solid Dispersions Using a Combined UV/FTIR/XPS/ssNMR Study

(2015) Yang Song et al.   MOLECULAR PHARMACEUTICS

Phase Separation Kinetics in Amorphous Solid Dispersions Upon Exposure to Water

(2015) Hitesh S. Purohit et al.   MOLECULAR PHARMACEUTICS

Using Environment-Sensitive Fluorescent Probes to Characterize Liquid-Liquid Phase Separation in Supersaturated Solutions of Poorly Water Soluble Compounds

(2015) Shweta A. Raina et al.   PHARMACEUTICAL RESEARCH

Investigation of the Functional Role of P-Glycoprotein in Limiting the Oral Bioavailability of Lumefantrine

(2013) Wahajuddin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Liquid–Liquid Phase Separation in Highly Supersaturated Aqueous Solutions of Poorly Water-Soluble Drugs: Implications for Solubility Enhancing Formulations

(2013) Grace A. Ilevbare et al.   CRYSTAL GROWTH & DESIGN

Determination of artemether and lumefantrine in anti-malarial fixed-dose combination tablets by microemulsion electrokinetic chromatography with short-end injection procedure

(2013) N’Cho Amin et al.   MALARIA JOURNAL

Influence of Additives on the Properties of Nanodroplets Formed in Highly Supersaturated Aqueous Solutions of Ritonavir

(2013) Grace A. Ilevbare et al.   MOLECULAR PHARMACEUTICS

Design and evaluation of Lumefantrine – Oleic acid self nanoemulsifying ionic complex for enhanced dissolution

(2013) Ketan Patel et al.   DARU-Journal of Pharmaceutical Sciences

Solution Behavior of PVP-VA and HPMC-AS-Based Amorphous Solid Dispersions and Their Bioavailability Implications

(2012) Feng Qian et al.   PHARMACEUTICAL RESEARCH

Possible treatment failure of artemether-lumefantrine in an Italian traveler with uncomplicated falciparum malaria.

(2011) Ernestina Carla Repetto et al.   Mediterranean Journal of Hematology and Infectious Diseases

A Classification System to Assess the Crystallization Tendency of Organic Molecules from Undercooled Melts

(2010) Jared A. Baird et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Pharmaceutical applications of cyclodextrins: basic science and product development

(2010) Thorsteinn Loftsson et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Supersaturating Drug Delivery Systems: The Answer to Solubility-Limited Oral Bioavailability?

(2009) Joachim Brouwers et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Coartem®: the journey to the clinic

(2009) Zulfiqarali G Premji   MALARIA JOURNAL

Phase Behavior of Poly(vinylpyrrolidone) Containing Amorphous Solid Dispersions in the Presence of Moisture

(2009) Alfred C. F. Rumondor et al.   MOLECULAR PHARMACEUTICS

Effect of Polymer Hygroscopicity on the Phase Behavior of Amorphous Solid Dispersions in the Presence of Moisture

(2009) Alfred C. F. Rumondor et al.   MOLECULAR PHARMACEUTICS

Effects of Polymer Type and Storage Relative Humidity on the Kinetics of Felodipine Crystallization from Amorphous Solid Dispersions

(2009) Alfred C. F. Rumondor et al.   PHARMACEUTICAL RESEARCH