SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity

Evaluating totipotency using criteria of increasing stringency

(2021) Eszter Posfai et al.   NATURE CELL BIOLOGY

Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis

(2021) Alejandro Aguilera-Castrejon et al.   NATURE

SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States

(2020) Kaixin Wu et al.   Cell Reports

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

(2020) Aditya Sankar et al.   NATURE CELL BIOLOGY

Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells

(2020) Ilan Theurillat et al.   Cell Reports

H1 histones control the epigenetic landscape by local chromatin compaction

(2020) Michael A. Willcockson et al.   NATURE

Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture

(2020) Nevin Yusufova et al.   NATURE

Gene-Specific H1 Eviction through a Transcriptional Activator→p300→NAP1→H1 Pathway

(2019) Miho Shimada et al.   MOLECULAR CELL

DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program

(2019) Yao-Long Yan et al.   PLOS BIOLOGY

Organization of Chromatin by Intrinsic and Regulated Phase Separation

(2019) Bryan A. Gibson et al.   CELL

Reprogramming of H3K9me3-dependent heterochromatin during mammalian embryo development

(2018) Chenfei Wang et al.   NATURE CELL BIOLOGY

Dynamics of the epigenetic landscape during the maternal-to-zygotic transition

(2018) Melanie A. Eckersley-Maslin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

(2018) Nofar Mor et al.   Cell Stem Cell

A Robust Method for the Purification and Characterization of Recombinant Human Histone H1 Variants

(2018) Adewola Osunsade et al.   BIOCHEMISTRY

CARM1 and Paraspeckles Regulate Pre-implantation Mouse Embryo Development

(2018) Anna Hupalowska et al.   CELL

SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States

(2018) Jack-Christophe Cossec et al.   Cell Stem Cell

Novel Roles for SUMOylation in Cellular Plasticity

(2018) Bruno Di Stefano et al.   TRENDS IN CELL BIOLOGY

Dynamic changes in H1 subtype composition during epigenetic reprogramming

(2017) Annalisa Izzo et al.   JOURNAL OF CELL BIOLOGY

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

(2017) Loren M. Lasko et al.   NATURE

Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons

(2017) Peter G Hendrickson et al.   NATURE GENETICS

The interplay of epigenetic marks during stem cell differentiation and development

(2017) Yaser Atlasi et al.   NATURE REVIEWS GENETICS

Variants of core histones and their roles in cell fate decisions, development and cancer

(2017) Marcus Buschbeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Emerging roles of linker histones in regulating chromatin structure and function

(2017) Dmitry V. Fyodorov et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone H1 depletion triggers an interferon response in cancer cells via activation of heterochromatic repeats

(2017) Andrea Izquierdo-Bouldstridge et al.   NUCLEIC ACIDS RESEARCH

Protein Expression Landscape of Mouse Embryos during Pre-implantation Development

(2017) Yawei Gao et al.   Cell Reports

The landscape of accessible chromatin in mammalian preimplantation embryos

(2016) Jingyi Wu et al.   NATURE

The molecular hallmarks of epigenetic control

(2016) C. David Allis et al.   NATURE REVIEWS GENETICS

Histone variants on the move: substrates for chromatin dynamics

(2016) Paul B. Talbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

The linker histone H1.0 generates epigenetic and functional intratumor heterogeneity

(2016) C. M. Torres et al.   SCIENCE

A quantitative investigation of linker histone interactions with nucleosomes and chromatin

(2016) Alison E. White et al.   Scientific Reports

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

Systematic Identification of Factors for Provirus Silencing in Embryonic Stem Cells

(2015) Bin Xia Yang et al.   CELL

Mapping the journey from totipotency to lineage specification in the mouse embryo

(2015) Chuen Yan Leung et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

(2015) Tina Thorslund et al.   NATURE

The histone chaperone CAF-1 safeguards somatic cell identity

(2015) Sihem Cheloufi et al.   NATURE

Reprogramming the genome to totipotency in mouse embryos

(2015) Li-quan Zhou et al.   TRENDS IN CELL BIOLOGY

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Embryonic Development following Somatic Cell Nuclear Transfer Impeded by Persisting Histone Methylation

(2014) Shogo Matoba et al.   CELL

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Single-Cell RNA-Seq Reveals Dynamic, Random Monoallelic Gene Expression in Mammalian Cells

(2014) Q. Deng et al.   SCIENCE

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

Exploring the energetics of histone H1.1 and H1.4 duplex DNA interactions

(2013) V.R. Machha et al.   BIOPHYSICAL CHEMISTRY

An Electrophoretic Mobility Shift Assay Identifies a Mechanistically Unique Inhibitor of Protein Sumoylation

(2013) Yeong Sang Kim et al.   CHEMISTRY & BIOLOGY

Histone variant H3.3 maintains a decondensed chromatin state essential for mouse preimplantation development

(2013) C.-J. Lin et al.   DEVELOPMENT

SUMO: A Multifaceted Modifier of Chromatin Structure and Function

(2013) Caelin Cubeñas-Potts et al.   DEVELOPMENTAL CELL

Ubc9 Sumoylation Controls SUMO Chain Formation and Meiotic Synapsis in Saccharomyces cerevisiae

(2013) Helene Klug et al.   MOLECULAR CELL

Deterministic direct reprogramming of somatic cells to pluripotency

(2013) Yoach Rais et al.   NATURE

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

H2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-Renewal and Differentiation

(2012) Gangqing Hu et al.   Cell Stem Cell

Embryonic stem cell potency fluctuates with endogenous retrovirus activity

(2012) Todd S. Macfarlan et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Histone H1 Depletion Impairs Embryonic Stem Cell Differentiation

(2012) Yunzhe Zhang et al.   PLoS Genetics

Emerging roles of the SUMO pathway in development

(2011) Hilda Lomelí et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Lineage Conversion of Murine Extraembryonic Trophoblast Stem Cells to Pluripotent Stem Cells

(2011) P. Kuckenberg et al.   MOLECULAR AND CELLULAR BIOLOGY

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Proteomics Analysis of Nucleolar SUMO-1 Target Proteins upon Proteasome Inhibition

(2009) Vittoria Matafora et al.   MOLECULAR & CELLULAR PROTEOMICS

Depletion of Human Histone H1 Variants Uncovers Specific Roles in Gene Expression and Cell Growth

(2008) Mónica Sancho et al.   PLoS Genetics

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY