Atypical antipsychotic drugs deregulate the cholesterol metabolism of macrophage-foam cells by activating NOX-ROS-PPARγ-CD36 signaling pathway

Epigenetic histone modulations of PPARγ and related pathways contribute to olanzapine-induced metabolic disorders

(2020) Yueqing Su et al.   PHARMACOLOGICAL RESEARCH

The detrimental effect of asymmetric dimethylarginine on cholesterol efflux of macrophage foam cells: Role of the NOX/ROS signaling

(2019) Chia-Hui Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Polydatin Inhibits Adipose Tissue Inflammation and Ameliorates Lipid Metabolism in High-Fat-Fed Mice

(2019) Li Zheng et al.   Biomed Research International

CD36 and lipid metabolism in the evolution of atherosclerosis

(2018) Lei Zhao et al.   BRITISH MEDICAL BULLETIN

Oxidative stress in autoimmune rheumatic diseases

(2018) Miranda J. Smallwood et al.   FREE RADICAL BIOLOGY AND MEDICINE

The CD36-PPARγ Pathway in Metabolic Disorders

(2018) Loïze Maréchal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Systemic Inflammatory Response and Atherosclerosis: The Paradigm of Chronic Inflammatory Rheumatic Diseases

(2018) Aikaterini Arida et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CCN family member 1 deregulates cholesterol metabolism and aggravates atherosclerosis

(2018) Jin-Feng Zhao et al.   Acta Physiologica

NOXA1-dependent NADPH oxidase regulates redox signaling and phenotype of vascular smooth muscle cell during atherogenesis

(2018) Aleksandr E. Vendrov et al.   Redox Biology

Systemic and cell-specific mechanisms of vasculopathy induced by human immunodeficiency virus and highly active antiretroviral therapy

(2017) Grace C. Haser et al.   JOURNAL OF VASCULAR SURGERY

Targeting metabotropic glutamate receptors for novel treatments of schizophrenia

(2017) James Maksymetz et al.   Molecular Brain

Neurovascular Unit Dysfunction and Blood–Brain Barrier Hyperpermeability Contribute to Schizophrenia Neurobiology: A Theoretical Integration of Clinical and Experimental Evidence

(2017) Souhel Najjar et al.   Frontiers in Psychiatry

Activation of Peroxisome Proliferator-activated Receptor γ (PPARγ) and CD36 Protein Expression

(2016) Xiaoxiao Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Macrophage CD36 Expression and Cellular Oxidized Low Density Lipoprotein (oxLDL) Accumulation by Tamoxifen

(2016) Miao Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell Surface CD36 Protein in Monocyte/Macrophage Contributes to Phagocytosis during the Resolution Phase of Ischemic Stroke in Mice

(2016) Moon-Sook Woo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation

(2015) Sivareddy Kotla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage-mediated cholesterol handling in atherosclerosis

(2015) Dimitry A. Chistiakov et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Clozapine-Induced Cardiotoxicity: Role of Oxidative Stress, Tumour Necrosis Factor Alpha and NF-κβ

(2014) Basel A. Abdel-Wahab et al.   Cardiovascular Toxicology

Effects of second-generation antipsychotics on selected markers of one-carbon metabolism and metabolic syndrome components in first-episode schizophrenia patients

(2014) Błażej Misiak et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

No evidence for a role of the peroxisome proliferator-activated receptor gamma (PPARG) and adiponectin (ADIPOQ) genes in antipsychotic-induced weight gain

(2014) Eva J. Brandl et al.   PSYCHIATRY RESEARCH

Impaired Prefrontal-Basal Ganglia Functional Connectivity and Substantia Nigra Hyperactivity in Schizophrenia

(2013) Jong H. Yoon et al.   BIOLOGICAL PSYCHIATRY

Pharmacological inhibition of NOX reduces atherosclerotic lesions, vascular ROS and immune–inflammatory responses in diabetic Apoe −/− mice

(2013) E. Di Marco et al.   DIABETOLOGIA

Changes in oxidative stress markers in patients with schizophrenia: The effect of antipsychotic drugs

(2013) Meng-Chang Tsai et al.   PSYCHIATRY RESEARCH

Update on Cardiovascular Safety of PPARgamma Agonists and Relevance to Medicinal Chemistry and Clinical Pharmacology

(2012) Andreea Ciudin et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1

(2011) L.-C. Ching et al.   CARDIOVASCULAR RESEARCH

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia

(2011) Daniel J. Lodge et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue

(2011) Lee D Roberts et al.   GENOME BIOLOGY

Basal ganglia pathology in schizophrenia: dopamine connections and anomalies

(2010) Emma Perez-Costas et al.   JOURNAL OF NEUROCHEMISTRY

Antipsychotic drugs and obesity

(2010) Christoph U. Correll et al.   TRENDS IN MOLECULAR MEDICINE

The effects of the PPAR-γ agonist pioglitazone on plasma concentrations of circulating vasoactive factors in type II diabetes mellitus

(2009) R A de Boer et al.   JOURNAL OF HUMAN HYPERTENSION

Effects of antipsychotics and vitamin C on the formation of reactive oxygen species

(2009) P. Heiser et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Peroxisome Proliferator-Activated Receptor-γ–Mediated Effects in the Vasculature

(2008) Sheng Zhong Duan et al.   CIRCULATION RESEARCH