Loss of proximal tubular transcription factor Krüppel-like factor 15 exacerbates kidney injury through loss of fatty acid oxidation

Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis

(2021) Verónica Miguel et al.   JOURNAL OF CLINICAL INVESTIGATION

Krüppel-like factor 6–mediated loss of BCAA catabolism contributes to kidney injury in mice and humans

(2021) Sian E. Piret et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UCP2-induced hypoxia promotes lipid accumulation and tubulointerstitial fibrosis during ischemic kidney injury

(2020) Qingqing Ke et al.   Cell Death & Disease

Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury

(2020) Yuhei Kirita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation

(2020) Poonam Dhillon et al.   Cell Metabolism

Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα

(2019) Ning Liang et al.   Nature Communications

Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics

(2019) Paul T. Brinkkoetter et al.   Cell Reports

Defining the dynamic chromatin landscape of mouse nephron progenitors

(2019) Sylvia Hilliard et al.   Biology Open

Wnt9a Promotes Renal Fibrosis by Accelerating Cellular Senescence in Tubular Epithelial Cells

(2018) Congwei Luo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal tubule injury: a driving force toward chronic kidney disease

(2018) Bi-Cheng Liu et al.   KIDNEY INTERNATIONAL

Podocyte-Specific Induction of Krüppel-Like Factor 15 Restores Differentiation Markers and Attenuates Kidney Injury in Proteinuric Kidney Disease

(2018) Yiqing Guo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Advantages of Single-Nucleus over Single-Cell RNA Sequencing of Adult Kidney: Rare Cell Types and Novel Cell States Revealed in Fibrosis

(2018) Haojia Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

BioJupies: Automated Generation of Interactive Notebooks for RNA-Seq Data Analysis in the Cloud

(2018) Denis Torre et al.   Cell Systems

Tubule-Derived Wnts Are Required for Fibroblast Activation and Kidney Fibrosis

(2017) Dong Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The loss of Krüppel-like factor 15 in Foxd1 + stromal cells exacerbates kidney fibrosis

(2017) Xiangchen Gu et al.   KIDNEY INTERNATIONAL

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

(2017) Weinan Du et al.   Nature Communications

Krüppel–Like Factor 15 Mediates Glucocorticoid-Induced Restoration of Podocyte Differentiation Markers

(2016) Sandeep K. Mallipattu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

PPARgene: A Database of Experimentally Verified and Computationally Predicted PPAR Target Genes

(2016) Li Fang et al.   PPAR Research

Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker

(2015) Wenjun Ju et al.   Science Translational Medicine

KLF15 and PPARαCooperate to Regulate Cardiomyocyte Lipid Gene Expression and Oxidation

(2015) Domenick A. Prosdocimo et al.   PPAR Research

The characteristic direction: a geometrical approach to identify differentially expressed genes

(2014) Neil R Clark et al.   BMC BIOINFORMATICS

Kruppel-like Factor 15 Is a Critical Regulator of Cardiac Lipid Metabolism

(2014) Domenick A. Prosdocimo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sonic Hedgehog Is a Novel Tubule-Derived Growth Factor for Interstitial Fibroblasts after Kidney Injury

(2014) D. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

(2014) Hyun Mi Kang et al.   NATURE MEDICINE

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Kruppel-like factor 15 is critical for vascular inflammation

(2013) Yuan Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

Kruppel-Like Factor 15 Modulates Renal Interstitial Fibrosis by ERK/MAPK and JNK/MAPK Pathways Regulation

(2013) Xiang Gao et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Krüppel-like Factor 15 (KLF15) Is a Key Regulator of Podocyte Differentiation

(2012) Sandeep K. Mallipattu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aristolochic acid-associated urothelial cancer in Taiwan

(2012) C.-H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways

(2012) B. N. Chau et al.   Science Translational Medicine

Extensive chromatin remodelling and establishment of transcription factor ‘hotspots’ during early adipogenesis

(2011) Rasmus Siersbaek et al.   EMBO JOURNAL

Physiological and Molecular Characterization of Aristolochic Acid Transport by the Kidney

(2011) K. G. Dickman et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Low-protein diet supplemented with ketoacids reduces the severity of renal disease in 5/6 nephrectomized rats: a role for KLF15

(2011) Xiang Gao et al.   KIDNEY INTERNATIONAL

ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments

(2010) Alexander Lachmann et al.   BIOINFORMATICS

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

Yamanaka factors critically regulate the developmental signaling network in mouse embryonic stem cells

(2008) Xiaosong Liu et al.   CELL RESEARCH