Photochemical C–F Activation Enables Defluorinative Alkylation of Trifluoroacetates and -Acetamides

Photochemical C–H Activation Enables Nickel-Catalyzed Olefin Dicarbofunctionalization

(2021) Mark W. Campbell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sequential C–F bond functionalizations of trifluoroacetamides and acetates via spin-center shifts

(2021) You-Jie Yu et al.   SCIENCE

Diethylzinc-Mediated Radical 1,2-Addition of Alkenes and Alkynes

(2021) Xin Li et al.   ORGANIC LETTERS

Non-innocent Radical Ion Intermediates in Photoredox Catalysis: Parallel Reduction Modes Enable Coupling of Diverse Aryl Chlorides

(2021) Alyah F. Chmiel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoredox-Catalyzed C–F Bond Allylation of Perfluoroalkylarenes at the Benzylic Position

(2021) Naoki Sugihara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radical Chain Reduction via Carbon Dioxide Radical Anion (CO2•–)

(2021) Cecilia M. Hendy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible-light photoredox-catalyzed selective carboxylation of C(sp3)−F bonds with CO2

(2021) Si-Shun Yan et al.   Chem

An Asymmetric Suzuki–Miyaura Approach to Prostaglandins: Synthesis of Tafluprost

(2020) Roman Kučera et al.   ORGANIC LETTERS

Selective Defluoroallylation of Trifluoromethylarenes

(2019) Chaosheng Luo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective C–F Functionalization of Unactivated Trifluoromethylarenes

(2019) David B. Vogt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Difluoro-Substituted Bicyclo[1.1.1]pentanes for Medicinal Chemistry: Design, Synthesis, and Characterization

(2019) Roman M. Bychek et al.   JOURNAL OF ORGANIC CHEMISTRY

Three-Component Olefin Dicarbofunctionalization Enabled by Nickel/Photoredox Dual Catalysis

(2019) Mark W. Campbell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nucleophilic difluoromethylation of aromatic aldehydes using trimethyl(trifluoromethyl)silane (TMSCF 3 )

(2018) Sankarganesh Krishnamoorthy et al.   JOURNAL OF FLUORINE CHEMISTRY

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

(2018) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Transition-Metal (Cu, Pd, Ni)-Catalyzed Difluoroalkylation via Cross-Coupling with Difluoroalkyl Halides

(2018) Zhang Feng et al.   ACCOUNTS OF CHEMICAL RESEARCH

Photoredox-Catalyzed Hydrodifluoroalkylation of Alkenes Using Difluorohaloalkyl Compounds and a Hantzsch Ester

(2017) Shuhei Sumino et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Defluoroalkylation of Trifluoromethylaromatics with Unactivated Alkenes

(2017) Hengbin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective Single C(sp3)–F Bond Cleavage in Trifluoromethylarenes: Merging Visible-Light Catalysis with Lewis Acid Activation

(2017) Kang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CF2H, a Hydrogen Bond Donor

(2017) Chanan D. Sessler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Photoredox-Catalyzed Reductive Difluoromethylation of Electron-Deficient Alkenes

(2015) Xiao-Jun Tang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

BrF 3 –KHF 2 : An air-stable fluorinating reagent

(2014) Toru Shishimi et al.   JOURNAL OF FLUORINE CHEMISTRY

Highly Selective gem-Difluoroallylation of Organoborons with Bromodifluoromethylated Alkenes Catalyzed by Palladium

(2014) Qiao-Qiao Min et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Main-Group Lewis Acids for C–F Bond Activation

(2013) Timo Stahl et al.   ACS Catalysis

Copper-Mediated Difluoromethylation of Aryl and Vinyl Iodides

(2012) Patrick S. Fier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Synthetic Route to a Dipeptidyl Peptidase-4 Inhibitor

(2012) Danny Lafrance et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

A New Method for Aromatic Difluoromethylation: Copper-Catalyzed Cross-Coupling and Decarboxylation Sequence from Aryl Iodides

(2011) Kenichi Fujikawa et al.   ORGANIC LETTERS

Selective difluoromethylation and monofluoromethylation reactions

(2009) Jinbo Hu et al.   CHEMICAL COMMUNICATIONS

Development of a Bulk Enabling Route to Maraviroc (UK-427,857), a CCR-5 Receptor Antagonist

(2008) Sarah J. Haycock-Lewandowski et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Electrochemical Carboxylation of α,α-Difluorotoluene Derivatives and Its Application to the Synthesis of α-Fluorinated Nonsteroidal Anti-Inflammatory Drugs

(2008) Hisanori Senboku et al.   SYNLETT