Strikingly Different Roles of SARS-CoV-2 Fusion Peptides Uncovered by Neutron Scattering

Enhanced Cholesterol-Dependent Hemifusion by Internal Fusion Peptide 1 of SARS Coronavirus-2 Compared to Its N-Terminal Counterpart

(2021) Gourab Prasad Pattnaik et al.   BIOCHEMISTRY

SARS-CoV-2 Fusion Peptide has a Greater Membrane Perturbating Effect than SARS-CoV with Highly Specific Dependence on Ca2+

(2021) Alex L. Lai et al.   JOURNAL OF MOLECULAR BIOLOGY

The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets

(2021) Thomas P. Peacock et al.   Nature Microbiology

Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry

(2021) Alessandra Luchini et al.   Scientific Reports

The CTNNBIP1-CLSTN1 fusion transcript regulates human neocortical development

(2021) Min-Yi Ou et al.   Cell Reports

Membranotropic and biological activities of the membrane fusion peptides from SARS-CoV spike glycoprotein: The importance of the complete internal fusion peptide domain

(2021) Luis Guilherme Mansor Basso et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

SnapShot: COVID-19

(2020) Blake Oberfeld et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

(2020) Shuai Xia et al.   CELL RESEARCH

The SARS-CoV-2 outbreak: What we know

(2020) Di Wu et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Coronavirus membrane fusion mechanism offers a potential target for antiviral development

(2020) Tiffany Tang et al.   ANTIVIRAL RESEARCH

The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity

(2020) Qianqian Li et al.   CELL

Distinct conformational states of SARS-CoV-2 spike protein

(2020) Yongfei Cai et al.   SCIENCE

Cholesterol 25‐Hydroxylase inhibits SARS ‐CoV‐2 and other coronaviruses by depleting membrane cholesterol

(2020) Shaobo Wang et al.   EMBO JOURNAL

Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion

(2020) Donald J. Benton et al.   NATURE

Structures and distributions of SARS-CoV-2 spike proteins on intact virions

(2020) Zunlong Ke et al.   NATURE

How cholesterol stiffens unsaturated lipid membranes

(2020) Saptarshi Chakraborty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuropilin-1 is a host factor for SARS-CoV-2 infection

(2020) James L. Daly et al.   SCIENCE

Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains

(2020) Tongqing Zhou et al.   Cell Host & Microbe

A small-angle neutron scattering study of the physical mechanism that drives the action of a viral fusion peptide

(2020) William T. Heller   CHEMISTRY AND PHYSICS OF LIPIDS

Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion

(2020) Ruochen Zang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

(2020) Steffen Klein et al.   Nature Communications

Human Coronavirus: Host-Pathogen Interaction

(2019) To Sing Fung et al.   Annual Review of Microbiology

A Fusion Peptide in the Spike Protein of MERS Coronavirus

(2019) Entedar A. J. Alsaadi et al.   Viruses-Basel

Towards generalized data reduction on a chopper-based time-of-flight neutron reflectometer

(2018) Philipp Gutfreund et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

A pH-correctable, DNA-based fluorescent reporter for organellar calcium

(2018) Nagarjun Narayanaswamy et al.   NATURE METHODS

The SARS-CoV Fusion Peptide Forms an Extended Bipartite Fusion Platform that Perturbs Membrane Order in a Calcium-Dependent Manner

(2017) Alex L. Lai et al.   JOURNAL OF MOLECULAR BIOLOGY

SNARE-mediated membrane fusion trajectories derived from force-clamp experiments

(2016) Marieelen Oelkers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aurore: new software for neutron reflectivity data analysis. Corrigendum

(2016) Yuri Gerelli   JOURNAL OF APPLIED CRYSTALLOGRAPHY

SARS-CoV fusion peptides induce membrane surface ordering and curvature

(2016) Luis G. M. Basso et al.   Scientific Reports

Tryptophan-Dependent Membrane Interaction and Heteromerization with the Internal Fusion Peptide by the Membrane Proximal External Region of SARS-CoV Spike Protein

(2015) Ying Liao et al.   BIOCHEMISTRY

Viral membrane fusion

(2015) Stephen C. Harrison   VIROLOGY

Lipid Organization of the Plasma Membrane

(2014) Helgi I. Ingólfsson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Production and Analysis of Perdeuterated Lipids from Pichia pastoris Cells

(2014) Alexis de Ghellinck et al.   PLoS One

Lipid Tail Protrusion in Simulations Predicts Fusogenic Activity of Influenza Fusion Peptide Mutants and Conformational Models

(2013) Per Larsson et al.   PLoS Computational Biology

Cholesterol-induced fluid membrane domains: A compendium of lipid-raft ternary phase diagrams

(2009) Derek Marsh   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Characterization of a Highly Conserved Domain within the Severe Acute Respiratory Syndrome Coronavirus Spike Protein S2 Domain with Characteristics of a Viral Fusion Peptide

(2009) I. G. Madu et al.   JOURNAL OF VIROLOGY