Hairpin-like siRNA-Based Spherical Nucleic Acids

A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma

(2021) Priya Kumthekar et al.   Science Translational Medicine

The effector mechanism of siRNA spherical nucleic acids

(2020) Gokay Yamankurt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The current state and future directions of RNAi-based therapeutics

(2019) Ryan L. Setten et al.   NATURE REVIEWS DRUG DISCOVERY

Rekindling RNAi Therapy: Materials Design Requirements for In Vivo siRNA Delivery

(2019) Byungji Kim et al.   ADVANCED MATERIALS

PLGA Spherical Nucleic Acids

(2018) Shengshuang Zhu et al.   ADVANCED MATERIALS

Using siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation in psoriasis

(2017) Houshang Nemati et al.   JOURNAL OF CONTROLLED RELEASE

What Controls the Hybridization Thermodynamics of Spherical Nucleic Acids?

(2015) Pratik S. Randeria et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown

(2015) Pratik S. Randeria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liposomal Spherical Nucleic Acids

(2014) Resham J. Banga et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Probing the inherent stability of siRNA immobilized on nanoparticle constructs

(2014) Stacey N. Barnaby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism for the endocytosis of spherical nucleic acid nanoparticle conjugates

(2013) C. H. J. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma

(2013) S. A. Jensen et al.   Science Translational Medicine

Spherical Nucleic Acids

(2012) Joshua I. Cutler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Topical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation

(2012) Dan Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient and targeted delivery of siRNA in vivo

(2010) Min Suk Shim et al.   FEBS Journal

Promise and Challenge of RNA Interference–Based Therapy for Cancer

(2010) Fabio Petrocca et al.   JOURNAL OF CLINICAL ONCOLOGY

Gene Regulation with Polyvalent siRNA−Nanoparticle Conjugates

(2009) David A. Giljohann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polyvalent DNA Nanoparticle Conjugates Stabilize Nucleic Acids

(2008) Dwight S. Seferos et al.   NANO LETTERS

Lateral Diffusion of Thiol Ligands on the Surface of Au Nanoparticles:  An Electron Paramagnetic Resonance Study

(2007) Petre Ionita et al.   ANALYTICAL CHEMISTRY