Transferrin receptor 1: a target for antibody-mediated cancer therapy

Transferrin receptor regulates pancreatic cancer growth by modulating mitochondrial respiration and ROS generation

(2016) Seung Min Jeong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Efficacy of an Anti-transferrin Receptor 1 Antibody Against AIDS-related Non-Hodgkin Lymphoma

(2015) Tracy R. Daniels-Wells et al.   JOURNAL OF IMMUNOTHERAPY

Insights into the effector functions of human IgG3 in the context of an antibody targeting transferrin receptor 1

(2015) Lai Sum Leoh et al.   MOLECULAR IMMUNOLOGY

Evaluation of Efficacy of Radioimmunotherapy with 90Y-Labeled Fully Human Anti-Transferrin Receptor Monoclonal Antibody in Pancreatic Cancer Mouse Models

(2015) Aya Sugyo et al.   PLoS One

Gene delivery in malignant B cells using the combination of lentiviruses conjugated to anti-transferrin receptor antibodies and an immunoglobulin promoter

(2014) Lai Sum Leoh et al.   JOURNAL OF GENE MEDICINE

Development of a complete human anti-human transferrin receptor C antibody as a novel marker of oral dysplasia and oral cancer

(2014) Kentaro Nagai et al.   Cancer Medicine

Phase I Study of a Systemically Delivered p53 Nanoparticle in Advanced Solid Tumors

(2013) Neil Senzer et al.   MOLECULAR THERAPY

Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier

(2013) J. A. Couch et al.   Science Translational Medicine

TfR1 interacts with the IKK complex and is involved in IKK–NF-κB signalling

(2012) Niall S. Kenneth et al.   BIOCHEMICAL JOURNAL

Insights into the mechanism of cell death induced by saporin delivered into cancer cells by an antibody fusion protein targeting the transferrin receptor 1

(2012) Tracy R. Daniels-Wells et al.   TOXICOLOGY IN VITRO

The transferrin receptor and the targeted delivery of therapeutic agents against cancer

(2011) Tracy R. Daniels et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

An Antibody-based Multifaceted Approach Targeting the Human Transferrin Receptor for the Treatment of B-cell Malignancies

(2011) Tracy R. Daniels et al.   JOURNAL OF IMMUNOTHERAPY

Lethal iron deprivation induced by non-neutralizing antibodies targeting transferrin receptor 1 in malignant B cells

(2011) José A. Rodríguez et al.   LEUKEMIA & LYMPHOMA

Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target

(2011) Y. J. Yu et al.   Science Translational Medicine

Development of Human Single-Chain Antibodies to the Transferrin Receptor that Effectively Antagonize the Growth of Leukemias and Lymphomas

(2010) R. Crepin et al.   CANCER RESEARCH