ApoE4 increases susceptibility to stress-induced age-dependent depression-like behavior and cognitive impairment

Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines

(2021) Peng Cao et al.   NEURON

Apolipoprotein E promotes white matter remodeling via the Dab1‐dependent pathway after traumatic brain injury

(2020) Zhi‐Jian Huang et al.   CNS Neuroscience & Therapeutics

Microglia, Lifestyle Stress, and Neurodegeneration

(2020) Charlotte Madore et al.   IMMUNITY

Cyclical administration of corticosterone results in aggravation of depression-like behaviors and accompanying downregulations in reelin in an animal model of chronic stress relevant to human recurrent depression

(2020) Katherina A. Lebedeva et al.   PHYSIOLOGY & BEHAVIOR

Apolipoprotein E/Aβ Complex Accumulates in AD Cortical Synapses via apoE Receptors and Is Enhanced by APOE4

(2019) Tina Bilousova et al.   AMERICAN JOURNAL OF PATHOLOGY

BDNF and COMT, but not APOE, alleles are associated with psychiatric symptoms in refractory epilepsy

(2019) Christine Doherty et al.   EPILEPSY & BEHAVIOR

Prevalence and correlates of mild cognitive impairment among diverse Hispanics/Latinos: Study of Latinos-Investigation of Neurocognitive Aging results

(2019) Hector M. González et al.   Alzheimers & Dementia

Stress-Induced Neuronal Colony Stimulating Factor 1 Provokes Microglia-Mediated Neuronal Remodeling and Depressive-like Behavior

(2018) Eric S. Wohleb et al.   BIOLOGICAL PSYCHIATRY

Apolipoprotein E, periodontal disease and the risk for atherosclerosis: a review

(2018) L.C. Pereira et al.   ARCHIVES OF ORAL BIOLOGY

The ApoE receptors Vldlr and Apoer2 in central nervous system function and disease

(2017) Courtney Lane-Donovan et al.   JOURNAL OF LIPID RESEARCH

Uncoupling DAPK1 from NMDA receptor GluN2B subunit exerts rapid antidepressant-like effects

(2017) S-X Li et al.   MOLECULAR PSYCHIATRY

Bexarotene protects against traumatic brain injury in mice partially through apolipoprotein E

(2017) Jianjun Zhong et al.   NEUROSCIENCE

ApoE Influences the Blood-Brain Barrier Through the NF-κB/MMP-9 Pathway After Traumatic Brain Injury

(2017) Zhipeng Teng et al.   Scientific Reports

β-Amyloid, APOE and BDNF Genotype, and Depressive and Anxiety Symptoms in Cognitively Normal Older Women and Men

(2016) Sophie E. Holmes et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders

(2016) Robert W. Mahley   JOURNAL OF MOLECULAR MEDICINE-JMM

Apolipoprotein E Regulates Injury-Induced Activation of Hippocampal Neural Stem and Progenitor Cells

(2016) Sue Hong et al.   JOURNAL OF NEUROTRAUMA

Early-life stress leads to impaired spatial learning and memory in middle-aged ApoE4-TR mice

(2016) Lan-yan Lin et al.   Molecular Neurodegeneration

Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects

(2016) G M I Chowdhury et al.   MOLECULAR PSYCHIATRY

A 9-Year Prospective Population-Based Study on the Association Between the APOE*E4 Allele and Late-Life Depression in Sweden

(2015) Ingmar Skoog et al.   BIOLOGICAL PSYCHIATRY

APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice

(2015) De-shan Liu et al.   Molecular Neurodegeneration

The role of NMDA receptors in the pathophysiology and treatment of mood disorders

(2014) Mehdi Ghasemi et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

APOE genotype alters glial activation and loss of synaptic markers in mice

(2012) Yuangui Zhu et al.   GLIA

ApoE4 and late onset depression in Indian population

(2012) R. Sureshkumar et al.   JOURNAL OF AFFECTIVE DISORDERS

Clozapine-Associated Colitis

(2012) Keith Richard Linsley et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents

(2012) Ronald S. Duman et al.   TRENDS IN NEUROSCIENCES

Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer’s disease and apoE TR mouse cortex

(2011) Stephen Arold et al.   ACTA NEUROPATHOLOGICA

Reelin, a Marker of Stress Resilience in Depression and Psychosis

(2011) S Hossein Fatemi   NEUROPSYCHOPHARMACOLOGY

Overexpression of Reelin Prevents the Manifestation of Behavioral Phenotypes Related to Schizophrenia and Bipolar Disorder

(2011) Cátia M Teixeira et al.   NEUROPSYCHOPHARMACOLOGY

Apolipoprotein E polymorphism and gender difference in outcome after severe traumatic brain injury

(2010) M. ÖST et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Synergistic associations of depression and apolipoprotein E genotype with incidence of dementia

(2010) Jae-Min Kim et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Apolipoprotein E isoform-dependent effects on anxiety and cognition in female TR mice

(2010) Jessica A. Siegel et al.   NEUROBIOLOGY OF AGING

Emerging role of glutamate in the pathophysiology of major depressive disorder

(2009) Kenji Hashimoto   BRAIN RESEARCH REVIEWS

ApoE4 Decreases Spine Density and Dendritic Complexity in Cortical Neurons In Vivo

(2009) S. B. Dumanis et al.   JOURNAL OF NEUROSCIENCE

Reduced levels of human apoE4 protein in an animal model of cognitive impairment

(2009) P.M. Sullivan et al.   NEUROBIOLOGY OF AGING

Reelin Secreted by GABAergic Neurons Regulates Glutamate Receptor Homeostasis

(2009) Cecilia Gonzalez Campo et al.   PLoS One

Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks

(2008) Alexandra Bour et al.   BEHAVIOURAL BRAIN RESEARCH

Antipsychotic-Induced Hyperprolactinemia

(2008) Erik Johnsen et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels

(2008) D. R. Riddell et al.   JOURNAL OF NEUROSCIENCE

The Reelin Signaling Pathway Promotes Dendritic Spine Development in Hippocampal Neurons

(2008) S. Niu et al.   JOURNAL OF NEUROSCIENCE