Electrostatically Driven Protein–Protein Interactions: Quantitative Prediction of Second Osmotic Virial Coefficients to Aid Antibody Design

Toward a Suite of Coarse-Grained Models for Molecular Simulation of Monoclonal Antibodies and Therapeutic Proteins

(2021) Hassan Shahfar et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Considerations for the Design of Antibody-Based Therapeutics

(2019) Dennis R. Goulet et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Computational approaches to therapeutic antibody design: established methods and emerging trends

(2019) Richard A Norman et al.   BRIEFINGS IN BIOINFORMATICS

Identifying Key Residues That Drive Strong Electrostatic Attractions between Therapeutic Antibodies

(2019) Glenn M. Ferreira et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Principles of Protein Stability and Their Application in Computational Design

(2018) Adi Goldenzweig et al.   Annual Review of Biochemistry

Rational optimization of a monoclonal antibody for simultaneous improvements in its solution properties and biological activity

(2018) Sandeep Kumar et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Electrostatically Mediated Protein-Protein Interactions for Monoclonal Antibodies: A Combined Experimental and Coarse-Grained Molecular Modeling Approach

(2018) Glenn M. Ferreira et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The CamSol Method of Rational Design of Protein Mutants with Enhanced Solubility

(2015) Pietro Sormanni et al.   JOURNAL OF MOLECULAR BIOLOGY

PASTA 2.0: an improved server for protein aggregation prediction

(2014) Ian Walsh et al.   NUCLEIC ACIDS RESEARCH

Theoretical aspects of self-assembly of proteins: A Kirkwood-Buff-theory approach

(2013) Arieh Ben-Naim   JOURNAL OF CHEMICAL PHYSICS

Toward aggregation-resistant antibodies by design

(2013) Christine C. Lee et al.   TRENDS IN BIOTECHNOLOGY

Weak Interactions Govern the Viscosity of Concentrated Antibody Solutions: High-Throughput Analysis Using the Diffusion Interaction Parameter

(2012) Brian D. Connolly et al.   BIOPHYSICAL JOURNAL

Solution pH That Minimizes Self-Association of Three Monoclonal Antibodies Is Strongly Dependent on Ionic Strength

(2012) Shantanu V. Sule et al.   MOLECULAR PHARMACEUTICS

The Influence of Charge Distribution on Self-Association and Viscosity Behavior of Monoclonal Antibody Solutions

(2012) Sandeep Yadav et al.   MOLECULAR PHARMACEUTICS

Reexamining protein–protein and protein–solvent interactions from Kirkwood-Buff analysis of light scattering in multi-component solutions

(2011) Marco A. Blanco et al.   JOURNAL OF CHEMICAL PHYSICS

Aggregation in Protein-Based Biotherapeutics: Computational Studies and Tools to Identify Aggregation-Prone Regions

(2011) Neeraj J. Agrawal et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Exploring the sequence determinants of amyloid structure using position-specific scoring matrices

(2010) Sebastian Maurer-Stroh et al.   NATURE METHODS

Identifying the amylome, proteins capable of forming amyloid-like fibrils

(2010) Lukasz Goldschmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design of therapeutic proteins with enhanced stability

(2009) N. Chennamsetty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Zyggregator method for predicting protein aggregation propensities

(2008) Gian Gaetano Tartaglia et al.   CHEMICAL SOCIETY REVIEWS

Prediction of Aggregation-Prone Regions in Structured Proteins

(2008) Gian Gaetano Tartaglia et al.   JOURNAL OF MOLECULAR BIOLOGY