Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice

The diabetes gene Zfp69 modulates hepatic insulin sensitivity in mice

(2015) Bomee Chung et al.   DIABETOLOGIA

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

(2015) Suna Onengut-Gumuscu et al.   NATURE GENETICS

Molecular Signatures Differentiate Immune States in Type 1 Diabetic Families

(2014) Yi-Guang Chen et al.   DIABETES

A Type I Interferon Transcriptional Signature Precedes Autoimmunity in Children Genetically at Risk for Type 1 Diabetes

(2014) R. C. Ferreira et al.   DIABETES

Innate Immune Activity Is Detected Prior to Seroconversion in Children With HLA-Conferred Type 1 Diabetes Susceptibility

(2014) H. Kallionpaa et al.   DIABETES

Fine mapping of type 1 diabetes regions Idd9.1 and Idd9.2 reveals genetic complexity

(2013) Emma E. Hamilton-Williams et al.   MAMMALIAN GENOME

Breakdown in Peripheral Tolerance in Type 1 Diabetes in Mice and Humans

(2013) L. T. Jeker et al.   Cold Spring Harbor Perspectives in Medicine

The B10 Idd9.3 Locus Mediates Accumulation of Functionally Superior CD137+ Regulatory T Cells in the Nonobese Diabetic Type 1 Diabetes Model

(2012) K. Kachapati et al.   JOURNAL OF IMMUNOLOGY

Subcongenic Analyses Reveal Complex Interactions between Distal Chromosome 4 Genes Controlling Diabetogenic B Cells and CD4 T Cells in Nonobese Diabetic Mice

(2012) J. Stolp et al.   JOURNAL OF IMMUNOLOGY

Type 1 Diabetes-Associated IL2RA Variation Lowers IL-2 Signaling and Contributes to Diminished CD4+CD25+ Regulatory T Cell Function

(2012) G. Garg et al.   JOURNAL OF IMMUNOLOGY

Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes

(2012) Julien Diana et al.   NATURE MEDICINE

Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes

(2011) Stephanie A. McClymont et al.   JOURNAL OF IMMUNOLOGY

Idd9.2 and Idd9.3 Protective Alleles Function in CD4+ T-Cells and Nonlymphoid Cells to Prevent Expansion of Pathogenic Islet-Specific CD8+ T-Cells

(2010) E. E. Hamilton-Williams et al.   DIABETES

A recombination hotspot leads to sequence variability within a novel gene (AK005651) and contributes to type 1 diabetes susceptibility

(2010) I. K. L. Tan et al.   GENOME RESEARCH

Etiology of Type 1 Diabetes

(2010) John A. Todd   IMMUNITY

Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease

(2010) John P. Driver et al.   Seminars in Immunopathology

Regulatory T cells and inhibitory cytokines in autoimmunity

(2009) Maria Bettini et al.   CURRENT OPINION IN IMMUNOLOGY

Idd9.1 Locus Controls the Suppressive Activity of FoxP3+CD4+CD25+ Regulatory T-Cells

(2009) J. Yamanouchi et al.   DIABETES

Defects in IL-2R Signaling Contribute to Diminished Maintenance of FOXP3 Expression in CD4+CD25+ Regulatory T-Cells of Type 1 Diabetic Subjects

(2009) S. A. Long et al.   DIABETES

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Positional Cloning of Zinc Finger Domain Transcription Factor Zfp69, a Candidate Gene for Obesity-Associated Diabetes Contributed by Mouse Locus Nidd/SJL

(2009) Stephan Scherneck et al.   PLoS Genetics

In vivo-activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host disease

(2008) D. Zhao et al.   BLOOD

Idd9/11 Genetic Locus Regulates Diabetogenic Activity of CD4 T-Cells in Nonobese Diabetic (NOD) Mice

(2008) Y.-G. Chen et al.   DIABETES