α-Keto Acids as Triggers and Partners for the Synthesis of Quinazolinones, Quinoxalinones, Benzooxazinones, and Benzothiazoles in Water

Synthesis of Benzothiazoles via Photooxidative Decarboxylation of α‐Keto Acids

(2020) Aparna Monga et al.   ADVANCED SYNTHESIS & CATALYSIS

Recent Advances in Synthesis of Benzothiazole Compounds Related to Green Chemistry

(2020) Xiang Gao et al.   MOLECULES

Clean Preparation of Quinolin-2-yl Substituted Ureas in Water

(2019) Long-Yong Xie et al.   ACS Sustainable Chemistry & Engineering

α-Keto Acids: Acylating Agents in Organic Synthesis

(2019) Filipe Penteado et al.   CHEMICAL REVIEWS

Progress in the Chemistry of Tetrahydroquinolines

(2019) Isravel Muthukrishnan et al.   CHEMICAL REVIEWS

Synthesis of Quinazoline and Quinazolinone Derivatives via Ligand-Promoted Ruthenium-Catalyzed Dehydrogenative and Deaminative Coupling Reaction of 2-Aminophenyl Ketones and 2-Aminobenzamides with Amines

(2019) Pandula T. Kirinde Arachchige et al.   ORGANIC LETTERS

Quinazolinone Synthesis through Base-Promoted SNAr Reaction of ortho-Fluorobenzamides with Amides Followed by Cyclization

(2019) Muhammad Asif Iqbal et al.   ACS Omega

A Review on Domino Condensation/Cyclization Reactions for the Synthesis of 2-Substituted 1,3-Benzothiazole Derivatives

(2019) Xing Liu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Remarkably flexible quinazolinones—synthesis and biological applications

(2019) Manne Madhava Reddy et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Controllable assembly of the benzothiazole framework using a CC triple bond as a one-carbon synthon

(2018) Yubing Huang et al.   CHEMICAL COMMUNICATIONS

Metal-free benzannulation of yne-allenone esters for atom economical synthesis of functionalized 1-naphthols

(2018) Hong-Kai Sha et al.   GREEN CHEMISTRY

Palladium-Catalyzed Oxidative Three-Component Coupling of Anthranilamides with Isocyanides and Arylboronic Acids: Access to 2,3-Disubstituted Quinazolinones

(2018) Chun Qian et al.   JOURNAL OF ORGANIC CHEMISTRY

Quinoxalinone as a Privileged Platform in Drug Development

(2018) Leilei Shi et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Water-promoted C-S bond formation reactions

(2018) Peizhong Xie et al.   Nature Communications

Ready Access to 3-Substituted Quinoxalin-2-ones under Superparamagnetic Nanoparticle Catalysis

(2018) Oanh T. K. Nguyen et al.   ChemistrySelect

Exogenous Photosensitizer-, Metal-, and Base-Free Visible-Light-Promoted C–H Thiolation via Reverse Hydrogen Atom Transfer

(2018) Ze-Ming Xu et al.   ORGANIC LETTERS

α-Keto Acids as Acylating Agents in the Synthesis of 2-Substituted Benzothiazoles and Benzoselenazoles

(2017) David B. Lima et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

One-pot copper-catalyzed synthesis of 2-substituted benzothiazoles from 2-iodoanilines, benzyl chlorides and elemental sulfur

(2017) Zhao Yang et al.   TETRAHEDRON LETTERS

Decarboxylative Coupling ofα-Keto Acids withortho-Phenylenediamines Promoted by an Electrochemical Method in Aqueous Media

(2016) Hai-Bin Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Formation of amides, their intramolecular reactions for the synthesis of N-heterocycles, and preparation of a marketed drug, sildenafil: a comprehensive coverage

(2016) Joydev K. Laha et al.   CHEMICAL COMMUNICATIONS

Synthesis of 2,3-Disubstituted Quinazolinone Derivatives through Copper Catalyzed C-H Amidation Reactions

(2016) Trimurtulu Kotipalli et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Niobium-promoted reaction of α-phenylglyoxylic acid with ortho-functionalized anilines: synthesis of 2-arylbenzothiazoles and 3-aryl-2H-benzo[b][1,4]benzoxazin-2-ones

(2016) Filipe Penteado et al.   GREEN CHEMISTRY

Synthesis, biological evaluation of 2,3-disubstituted-imidazolyl/benzimidazolyl-quinazolin-4(3H)-one derivatives

(2016) Dilip A. Patil et al.   MEDICINAL CHEMISTRY RESEARCH

Recent developments in transition metal catalysis for quinazolinone synthesis

(2016) T. M. M. Maiden et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Advanced Synthetic Strategies for Constructing Quinazolinone Scaffolds

(2016) Umesh Kshirsagar et al.   SYNTHESIS-STUTTGART

Bioactive thiazole and benzothiazole derivatives

(2015) Abdul Rouf et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A comprehensive review in current developments of benzothiazole-based molecules in medicinal chemistry

(2015) Rangappa S. Keri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthetic approaches, functionalization and therapeutic potential of quinazoline and quinazolinone skeletons: The advances continue

(2015) Imtiaz Khan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent developments in the chemistry of quinazolinone alkaloids

(2015) U. A. Kshirsagar   ORGANIC & BIOMOLECULAR CHEMISTRY

Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2

(2015) Ramzi F. Sweis et al.   ACS Medicinal Chemistry Letters

A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-π Interaction

(2014) Timothy P. C. Rooney et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design, synthesis and molecular docking study of novel quinoxalin-2(1H)-ones as anti-tumor active agents with inhibition of tyrosine kinase receptor and studying their cyclooxygenase-2 activity

(2014) Shadia A. Galal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Copper-Catalyzed Double C–S Bonds Formation via Different Paths: Synthesis of Benzothiazoles from N-Benzyl-2-iodoaniline and Potassium Sulfide

(2014) Xiaoyun Zhang et al.   ORGANIC LETTERS

Synthesis of quinazolinones from anthranilamides and aldehydes via metal-free aerobic oxidation in DMSO

(2014) Na Yeun Kim et al.   TETRAHEDRON LETTERS

Oxone-mediated oxidative carbon-heteroatom bond cleavage: synthesis of benzoxazinones from benzoxazoles with α-oxocarboxylic acids

(2014) Hua Wang et al.   RSC Advances

Recent advances in 4(3H)-quinazolinone syntheses

(2014) Lin He et al.   RSC Advances

Unexpected TFA-catalyzed tandem reaction of benzo[d]oxazoles with 2-oxo-2-arylacetic acids: synthesis of 3-aryl-2H-benzo[b][1,4]oxazin-2-ones and cephalandole A

(2014) Shaoxi Yan et al.   RSC Advances

Recent advances in the synthesis of 2-substituted benzothiazoles: a review

(2014) Neelam P. Prajapati et al.   RSC Advances

Rapid assembly of quinazolinone scaffold via copper-catalyzed tandem reaction of 2-bromobenzamides with aldehydes and aqueous ammonia: application to the synthesis of the alkaloid tryptanthrin

(2014) Shenghai Guo et al.   RSC Advances

Design, synthesis and mode of action of some benzothiazole derivatives bearing an amide moiety as antibacterial agents

(2014) Meenakshi Singh et al.   RSC Advances

Visible-light-induced, copper(i)-catalysed C–N coupling between o-phenylenediamine and terminal alkynes: one-pot synthesis of 3-phenyl-2-hydroxy-quinoxalines

(2013) Arunachalam Sagadevan et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

An Efficient Synthesis of Quinoxalinone Derivatives as Potent Inhibitors of Aldose Reductase

(2012) Yanchun Yang et al.   ChemMedChem

Palladium-Catalyzed Synthesis of Benzimidazoles and Quinazolinones from Common Precursors

(2012) Jessie E. R. Sadig et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd-Catalyzed Benzylic C–H Amidation with Benzyl Alcohols in Water: A Strategy To Construct Quinazolinones

(2012) Hidemasa Hikawa et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Biological Evaluation of New Quinoxaline Derivatives as Antioxidant and Anti-Inflammatory Agents

(2011) Asunción Burguete et al.   Chemical Biology & Drug Design

Green chemistry oriented organic synthesis in water

(2011) Marc-Olivier Simon et al.   CHEMICAL SOCIETY REVIEWS

Quinoxalin-2(1H)-One Derivatives As Inhibitors Against Hepatitis C Virus

(2011) Rui Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

The First General, Highly Enantioselective Lewis Base Organo- catalyzed Hydrosilylation of Benzoxazinones and Quinoxalinones

(2010) Zhou-Yang Xue et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: Novel antibacterial agents against Mycobacterium tuberculosis

(2010) Xiaokai Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Revisiting the Hinsberg Reaction: Facile and Expeditious Synthesis of 3-Substituted Quinoxalin-2(1H)-ones under Catalyst-Free Conditions in Water

(2010) Sabbavarapu Narayana Murthy et al.   HELVETICA CHIMICA ACTA

A convenient one-pot procedure for the synthesis of 2-aryl quinazolines using active MnO2 as oxidant

(2010) Yi-Yuan Peng et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Eco-friendly synthesis of 2-substituted benzothiazoles catalyzed by cetyltrimethyl ammonium bromide (CTAB) in water

(2010) Xiao-Liang Yang et al.   JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY

Effect of Ions on the Structure of Water: Structure Making and Breaking

(2009) Yizhak Marcus   CHEMICAL REVIEWS

Organic Synthesis “On Water”

(2009) Arani Chanda et al.   CHEMICAL REVIEWS

Development of novel 2-[4-(aminoalkoxy)phenyl]-4(3H)-quinazolinone derivatives as potent and selective histamine H3 receptor inverse agonists

(2008) Takashi Mizutani et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of Arylglyoxylic Acids and Their Collision-Induced Dissociation

(2008) Kuldeep Wadhwa et al.   SYNTHETIC COMMUNICATIONS