Gas6 induces inflammation and reduces plaque burden but worsens behavior in a sex-dependent manner in the APP/PS1 model of Alzheimer’s disease

Microglia use TAM receptors to detect and engulf amyloid β plaques

(2021) Youtong Huang et al.   NATURE IMMUNOLOGY

Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome

(2020) Irune Diaz-Aparicio et al.   JOURNAL OF NEUROSCIENCE

TAM Receptor Pathways at the Crossroads of Neuroinflammation and Neurodegeneration

(2019) Giacomo Tondo et al.   DISEASE MARKERS

The neuropathological diagnosis of Alzheimer’s disease

(2019) Michael A. DeTure et al.   Molecular Neurodegeneration

The Immune System Drives Synapse Loss During Lipopolysaccharide-Induced Learning and Memory Impairment in Mice

(2019) Yi-Rong Xin et al.   Frontiers in Aging Neuroscience

IL-1β-driven amyloid plaque clearance is associated with an expansion of transcriptionally reprogrammed microglia

(2019) Fátima Rivera-Escalera et al.   Journal of Neuroinflammation

Cranial irradiation mediated spine loss is sex-specific and complement receptor-3 dependent in male mice

(2019) Joshua J. Hinkle et al.   Scientific Reports

Axl activation attenuates neuroinflammation by inhibiting the TLR/TRAF/NF-κB pathway after MCAO in rats

(2018) Guangyong Wu et al.   NEUROBIOLOGY OF DISEASE

Sex-Specific Features of Microglia from Adult Mice

(2018) Alessandro Villa et al.   Cell Reports

Microglia in neurodegeneration

(2018) Suzanne Hickman et al.   NATURE NEUROSCIENCE

Jujuboside A promotes Aβ clearance and ameliorates cognitive deficiency in Alzheimer's disease through activating Axl/HSP90/PPARγ pathway

(2018) Mu Zhang et al.   Theranostics

CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN /PGRN

(2017) David W. Fardo et al.   EXPERIMENTAL GERONTOLOGY

Microglial Function across the Spectrum of Age and Gender

(2017) Jillian Nissen   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease

(2017) Zhuoran Yin et al.   NEUROBIOLOGY OF AGING

Assaying the Stability and Inactivation of AAV Serotype 1 Vectors

(2017) Douglas B. Howard et al.   Human Gene Therapy Methods

Requirement of Gamma-Carboxyglutamic Acid Modification and Phosphatidylserine Binding for the Activation of Tyro3, Axl, and Mertk Receptors by Growth Arrest-Specific 6

(2017) Ke Geng et al.   Frontiers in Immunology

Gas6 Promotes Oligodendrogenesis and Myelination in the Adult Central Nervous System and After Lysolecithin-Induced Demyelination

(2016) Salman Goudarzi et al.   ASN Neuro

Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model

(2016) Sung Hoon Baik et al.   GLIA

Recombinant Gas6 augments Axl and facilitates immune restoration in an intracerebral hemorrhage mouse model

(2016) Lu-sha Tong et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TAM receptors regulate multiple features of microglial physiology

(2016) Lawrence Fourgeaud et al.   NATURE

Nuclear Receptors License Phagocytosis by Trem2+ Myeloid Cells in Mouse Models of Alzheimer's Disease

(2015) J. C. Savage et al.   JOURNAL OF NEUROSCIENCE

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

(2014) Scott J. Webster et al.   Frontiers in Genetics

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

TAM Receptors Affect Adult Brain Neurogenesis by Negative Regulation of Microglial Cell Activation

(2013) R. Ji et al.   JOURNAL OF IMMUNOLOGY

Biology of the TAM Receptors

(2013) G. Lemke   Cold Spring Harbor Perspectives in Biology

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Involvement of Receptor Tyrosine Kinase Tyro3 in Amyloidogenic APP Processing and β-Amyloid Deposition in Alzheimer's Disease Models

(2012) Yan Zheng et al.   PLoS One

Plasma Based Markers of [11C] PiB-PET Brain Amyloid Burden

(2012) Steven John Kiddle et al.   PLoS One

Chronic IL-1β-Mediated Neuroinflammation Mitigates Amyloid Pathology in a Mouse Model of Alzheimer’s Disease without Inducing Overt Neurodegeneration

(2011) Sarah B. Matousek et al.   Journal of Neuroimmune Pharmacology

GAS6 Enhances Repair Following Cuprizone-Induced Demyelination

(2010) Vladislav Tsiperson et al.   PLoS One

Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1

(2010) Daniel J. Gough et al.   PLOS BIOLOGY

The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective

(2008) Solomon S Shaftel et al.   Journal of Neuroinflammation