Conformational Flexibility of Apolipoprotein A-I amino- and carboxy-Termini is necessary for Lipid Binding but not Cholesterol Efflux

First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation

(2020) Gregory Brubaker et al.   PLoS One

Diabetes Impairs Cellular Cholesterol Efflux From ABCA1 to Small HDL Particles

(2020) Yi He et al.   CIRCULATION RESEARCH

Is ABCA1 a lipid transfer protein?

(2018) Michael C. Phillips   JOURNAL OF LIPID RESEARCH

A thumbwheel mechanism for APOA1 activation of LCAT activity in HDL

(2018) Allison L. Cooke et al.   JOURNAL OF LIPID RESEARCH

Tertiary structure of apolipoprotein A-I in nascent high-density lipoproteins

(2018) Mohsen Pourmousa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N-terminal mutation of apoA-I and interaction with ABCA1 reveal mechanisms of nascent HDL biogenesis

(2018) Minjing Liu et al.   JOURNAL OF LIPID RESEARCH

A consensus model of human apolipoprotein A-I in its monomeric and lipid-free state

(2017) John T Melchior et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A consensus model of human apolipoprotein A-I in its monomeric and lipid-free state

(2017) John T Melchior et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Probing the C-terminal domain of lipid-free apoA-I demonstrates the vital role of the H10B sequence repeat in HDL formation

(2016) Xiaohu Mei et al.   JOURNAL OF LIPID RESEARCH

HDL Particle Size Is a Critical Determinant of ABCA1-Mediated Macrophage Cellular Cholesterol ExportNovelty and Significance

(2015) Xian-Ming Du et al.   CIRCULATION RESEARCH

Surface Density-Induced Pleating of a Lipid Monolayer Drives Nascent High-Density Lipoprotein Assembly

(2015) Jere P. Segrest et al.   STRUCTURE

ABCA1 dimer-monomer interconversion during HDL generation revealed by single-molecule imaging

(2013) K. O. Nagata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prebeta-1 HDL and coronary heart disease

(2012) John P. Kane et al.   CURRENT OPINION IN LIPIDOLOGY

New insights into the determination of HDL structure by apolipoproteins

(2012) Michael C. Phillips   JOURNAL OF LIPID RESEARCH

Is it time to revise the HDL cholesterol hypothesis?

(2012) Daniel J Rader et al.   NATURE MEDICINE

Apolipoprotein A-I helical structure and stability in discoidal high-density lipoprotein (HDL) particles by hydrogen exchange and mass spectrometry

(2012) P. Sevugan Chetty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trimerized apolipoprotein A-I (TripA) forms lipoproteins, activates lecithin:cholesterol acyltransferase, elicits lipid efflux, and is transported through aortic endothelial cells

(2011) Pascale M. Ohnsorg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Crystal Structure of C-terminal Truncated Apolipoprotein A-I Reveals the Assembly of High Density Lipoprotein (HDL) by Dimerization

(2011) Xiaohu Mei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessment of the Validity of the Double Superhelix Model for Reconstituted High Density Lipoproteins

(2010) Martin K. Jones et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Double Superhelix Model of High Density Lipoprotein

(2009) Zhiping Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Macrophage Cholesterol Exporter ABCA1 Functions as an Anti-inflammatory Receptor

(2009) Chongren Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Purification of recombinant apolipoproteins A-I and A-IV and efficient affinity tag cleavage by tobacco etch virus protease

(2009) Matthew R. Tubb et al.   JOURNAL OF LIPID RESEARCH

Apolipoprotein AI tertiary structures determine stability and phospholipid-binding activity of discoidal high-density lipoprotein particles of different sizes

(2009) Bin Chen et al.   PROTEIN SCIENCE