Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease

Exposure to a mixture of legacy, alternative, and replacement per- and polyfluoroalkyl substances (PFAS) results in sex-dependent modulation of cholesterol metabolism and liver injury

(2021) Katherine Roth et al.   ENVIRONMENT INTERNATIONAL

Gender differences in pharmacokinetics of perfluoropentanoic acid using non-linear mixed-effect modeling in rats

(2020) Go-Wun Choi et al.   ARCHIVES OF TOXICOLOGY

Sex Hormone-Dependent Physiology and Diseases of Liver

(2020) Paulina Kur et al.   International Journal of Environmental Research and Public Health

Perfluorooctanoic acid activates multiple nuclear receptor pathways and skews expression of genes regulating cholesterol homeostasis in liver of humanized PPARα mice fed an American diet

(2020) J.J. Schlezinger et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Sex-specific lipid molecular signatures in obesity-associated metabolic dysfunctions revealed by lipidomic characterization in ob/ob mouse

(2019) Marcela González-Granillo et al.   Biology of Sex Differences

Bile Acids as Metabolic Regulators and Nutrient Sensors

(2019) John Y. L. Chiang et al.   Annual Review of Nutrition

Using 2003–2014 U.S. NHANES data to determine the associations between per- and polyfluoroalkyl substances and cholesterol: Trend and implications

(2019) Zhaomin Dong et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Sex differences in metabolic regulation and diabetes susceptibility

(2019) Blandine Tramunt et al.   DIABETOLOGIA

Sex differences in the association between perfluoroalkyl acids and liver function in US adolescents: Analyses of NHANES 2013–2016

(2019) Roberta Attanasio   ENVIRONMENTAL POLLUTION

A curated knowledgebase on endocrine disrupting chemicals and their biological systems-level perturbations

(2019) Bagavathy Shanmugam Karthikeyan et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Binding specificities of estrogen receptor with perfluorinated compounds: A cross species comparison

(2019) Zhiqiang Qiu et al.   ENVIRONMENT INTERNATIONAL

Activation of human nuclear receptors by perfluoroalkylated substances (PFAS)

(2019) Anne-Cathrin Behr et al.   TOXICOLOGY IN VITRO

Association among total serum isomers of perfluorinated chemicals, glucose homeostasis, lipid profiles, serum protein and metabolic syndrome in adults: NHANES, 2013–2014

(2018) Hui-Shan Liu et al.   ENVIRONMENTAL POLLUTION

Temporal trends of PFSAs, PFCAs and selected precursors in Australian serum from 2002 to 2013

(2017) Ulrika Eriksson et al.   ENVIRONMENTAL POLLUTION

Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD

(2017) Na Jiao et al.   GUT

The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids

(2017) Puneet Puri et al.   HEPATOLOGY

Bile Acid Alterations Are Associated With Insulin Resistance, but Not With NASH, in Obese Subjects

(2017) Vanessa Legry et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Alteration of Bile Acid and Cholesterol Biosynthesis and Transport by Perfluorononanoic Acid (PFNA) in Mice

(2017) Yue Zhang et al.   TOXICOLOGICAL SCIENCES

Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease

(2016) Panu K. Luukkonen et al.   JOURNAL OF HEPATOLOGY

Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease

(2016) Marialena Mouzaki et al.   PLoS One

Persistent organic pollutants and non-alcoholic fatty liver disease in morbidly obese patients: a cohort study

(2015) Panu Rantakokko et al.   Environmental Health

Na+/Taurocholate Cotransporting Polypeptide and Apical Sodium-Dependent Bile Acid Transporter Are Involved in the Disposition of Perfluoroalkyl Sulfonates in Humans and Rats

(2015) Wen Zhao et al.   TOXICOLOGICAL SCIENCES

Sex Hormones and Their Receptors Regulate Liver Energy Homeostasis

(2015) Minqian Shen et al.   International Journal of Endocrinology

Plasma bile acids show a positive correlation with body mass index and are negatively associated with cognitive restraint of eating in obese patients

(2015) Philip Prinz et al.   Frontiers in Neuroscience

A metabolic view on menopause and ageing

(2014) Kirsi Auro et al.   Nature Communications

Human Insulin Resistance Is Associated With Increased Plasma Levels of 12 -Hydroxylated Bile Acids

(2013) R. A. Haeusler et al.   DIABETES

Associations between PFOA, PFOS and changes in the expression of genes involved in cholesterol metabolism in humans

(2013) Tony Fletcher et al.   ENVIRONMENT INTERNATIONAL

Modulation of ammonium perfluorooctanoate-induced hepatic damage by genetically different PPARα in mice

(2011) Tomohiko Nakagawa et al.   ARCHIVES OF TOXICOLOGY

Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis

(2011) Srinivasan Dasarathy et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Bile acid levels are increased in the liver of patients with steatohepatitis

(2009) Márcia M. Aranha et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes

(2009) D. J. Waxman et al.   MOLECULAR PHARMACOLOGY

Studies on the Toxicological Effects of PFOA and PFOS on Rats Using Histological Observation and Chemical Analysis

(2008) Lin Cui et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY