nr0b1 (DAX1) loss of function in zebrafish causes hypothalamic defects via abnormal progenitor proliferation and differentiation

Conserved Genoarchitecture of the Basal Hypothalamus in Zebrafish Embryos

(2020) Theresa Schredelseker et al.   Frontiers in Neuroanatomy

Lessons from expanded potential of embryonic stem cells: Moving toward totipotency

(2020) Rongrong Le et al.   Journal of Genetics and Genomics

Novel frameshift mutation of the NR0B1(DAX1) in two tall adult brothers

(2019) Rita Bertalan et al.   MOLECULAR BIOLOGY REPORTS

The Notch signaling pathway inhibitor Dapt alleviates autism-like behavior, autophagy and dendritic spine density abnormalities in a valproic acid-induced animal model of autism

(2019) Yinghua Zhang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Molecular identification of the Dyn/Kor system and its potential role in the reproductive axis of goldfish

(2018) Yali Liu et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Targeted in situ genome-wide profiling with high efficiency for low cell numbers

(2018) Peter J Skene et al.   Nature Protocols

UBTOR/KIAA1024 regulates neurite outgrowth and neoplasia through mTOR signaling

(2018) Hefei Zhang et al.   PLoS Genetics

The hypothalamus-pituitary-gonad axis: Tales of mice and men

(2017) Athina Kaprara et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites

(2017) Peter J Skene et al.   eLife

Control of the onset of puberty

(2016) Sarantis Livadas et al.   CURRENT OPINION IN PEDIATRICS

κ-Opioid Receptor Is Colocalized in GnRH and KNDy Cells in the Female Ovine and Rat Brain

(2016) Peyton W. Weems et al.   ENDOCRINOLOGY

nr0b1 (DAX1) mutation in zebrafish causes female-to-male sex reversal through abnormal gonadal proliferation and differentiation

(2016) Sijie Chen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Control of puberty onset and fertility by gonadotropin-releasing hormone neurons

(2016) Allan E. Herbison   Nature Reviews Endocrinology

Stereotyped initiation of retinal waves by bipolar cells via presynaptic NMDA autoreceptors

(2016) Rong-wei Zhang et al.   Nature Communications

Genetic Analysis of Zebrafish Gonadotropin (FSH and LH) Functions by TALEN-Mediated Gene Disruption

(2015) Zhiwei Zhang et al.   MOLECULAR ENDOCRINOLOGY

Early reprogramming regulators identified by prospective isolation and mass cytometry

(2015) Ernesto Lujan et al.   NATURE

European Consensus Statement on congenital hypogonadotropic hypogonadism—pathogenesis, diagnosis and treatment

(2015) Ulrich Boehm et al.   Nature Reviews Endocrinology

Nr0b1 is a negative regulator of Zscan4c in mouse embryonic stem cells

(2015) Setsuko Fujii et al.   Scientific Reports

The hypothalamus

(2014) Clifford B. Saper et al.   CURRENT BIOLOGY

Valproic acid, a histone deacetylase inhibitor, regulates cell proliferation in the adult zebrafish optic tectum

(2014) Miki Dozawa et al.   DEVELOPMENTAL DYNAMICS

Dax1 and Nanog act in parallel to stabilize mouse embryonic stem cells and induced pluripotency

(2014) Junlei Zhang et al.   Nature Communications

Notch signaling and proneural genes work together to control the neural building blocks for the initial scaffold in the hypothalamus

(2014) Michelle Ware et al.   Frontiers in Neuroanatomy

Notch/Rbpj  signaling regulates progenitor maintenance and differentiation of hypothalamic arcuate neurons

(2013) P. K. Aujla et al.   DEVELOPMENT

Gonad differentiation and puberty onset in the zebrafish: Evidence for the dependence of puberty onset on body growth but not age in females

(2013) Weiting Chen et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Uncovering the true identity of naïve pluripotent stem cells

(2013) Maaike Welling et al.   TRENDS IN CELL BIOLOGY

Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

(2012) Yosef Buganim et al.   CELL

Activation of Anorexigenic Pro-Opiomelanocortin Neurones during Refeeding is Independent of Vagal and Brainstem Inputs

(2012) C. Fekete et al.   JOURNAL OF NEUROENDOCRINOLOGY

An anatomically comprehensive atlas of the adult human brain transcriptome

(2012) Michael J. Hawrylycz et al.   NATURE

Allen Brain Atlas: an integrated spatio-temporal portal for exploring the central nervous system

(2012) Susan M. Sunkin et al.   NUCLEIC ACIDS RESEARCH

The Notch effector gene Hes1 regulates migration of hypothalamic neurons, neuropeptide content and axon targeting to the pituitary

(2011) Paven K. Aujla et al.   DEVELOPMENTAL BIOLOGY

Hypogonadotropic hypogonadism in subjects with DAX1 mutations

(2011) Unmesh Jadhav et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

(2011) Graciana Diez-Roux et al.   PLOS BIOLOGY

Neurokinin B and Dynorphin A in Kisspeptin Neurons of the Arcuate Nucleus Participate in Generation of Periodic Oscillation of Neural Activity Driving Pulsatile Gonadotropin-Releasing Hormone Secretion in the Goat

(2010) Y. Wakabayashi et al.   JOURNAL OF NEUROSCIENCE

Identification of a novel mutation in DAX1/NR0B1A gene in two siblings with severe clinical presentation of adrenal hypoplasia congenita

(2009) Rafael Machado Mantovani et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

Role of Neuroepithelial Sonic hedgehog in Hypothalamic Patterning

(2009) N.-E. Szabo et al.   JOURNAL OF NEUROSCIENCE

Long and winding roads: Testis differentiation in zebrafish

(2009) Laszlo Orban et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

30 years of dynorphins — New insights on their functions in neuropsychiatric diseases

(2009) Christoph Schwarzer   PHARMACOLOGY & THERAPEUTICS

Dax-1 Knockdown in Mouse Embryonic Stem Cells Induces Loss of Pluripotency and Multilineage Differentiation

(2009) Olfa Khalfallah et al.   STEM CELLS

Identification of Wnt-Responsive Cells in the Zebrafish Hypothalamus

(2009) Xu Wang et al.   Zebrafish

An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells

(2008) Jonghwan Kim et al.   CELL

Notch signaling regulates endocrine cell specification in the zebrafish anterior pituitary

(2008) Sunit Dutta et al.   DEVELOPMENTAL BIOLOGY

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

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