ATAD3A mediates activation of RAS-independent mitochondrial ERK1/2 signaling, favoring head and neck cancer development

Hepatitis B virus P protein initiates glycolytic bypass in HBV-related hepatocellular carcinoma via a FOXO3/miRNA-30b-5p/MINPP1 axis

(2021) Wenbiao Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Impacts of Environmental Factors on Head and Neck Cancer Pathogenesis and Progression

(2021) Marisol Miranda-Galvis et al.   Cells

Selectivity mechanism of phosphodiesterase isoform inhibitor through in silico investigations

(2021) Junhao Huang et al.   JOURNAL OF MOLECULAR MODELING

Circumventing AKT-Associated Radioresistance in Oral Cancer by Novel Nanoparticle-Encapsulated Capivasertib

(2020) Liwei Lang et al.   Cells

Emerging Links between Control of Mitochondrial Protein ATAD3A and Cancer

(2020) Liwei Lang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Very low intensity ultrasounds as a new strategy to improve selective delivery of nanoparticles-complexes in cancer cells

(2019) Rossella Loria et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Simultaneously inactivating Src and AKT by saracatinib/capivasertib co-delivery nanoparticles to improve the efficacy of anti-Src therapy in head and neck squamous cell carcinoma

(2019) Liwei Lang et al.   Journal of Hematology & Oncology

Novel ATAD3A recessive mutation associated to fatal cerebellar hypoplasia with multiorgan involvement and mitochondrial structural abnormalities

(2019) Susana Peralta et al.   MOLECULAR GENETICS AND METABOLISM

ATAD3 controls mitochondrial cristae structure in mouse muscle, influencing mtDNA replication and cholesterol levels

(2018) Susana Peralta et al.   JOURNAL OF CELL SCIENCE

Intracellular reduction in ATP levels contributes to CYT997-induced suppression of metastasis of head and neck squamous carcinoma

(2018) Xiangdong Zhao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The ERK and JNK pathways in the regulation of metabolic reprogramming

(2018) Salvatore Papa et al.   ONCOGENE

FGF19 amplification reveals an oncogenic dependency upon autocrine FGF19/FGFR4 signaling in head and neck squamous cell carcinoma

(2018) Lixia Gao et al.   ONCOGENE

Friend or foe? Mitochondria as a pharmacological target in cancer treatment

(2017) Tyler Dickerson et al.   Future Medicinal Chemistry

ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia

(2017) Helen M. Cooper et al.   HUMAN MOLECULAR GENETICS

Combined targeting of Arf1 and Ras potentiates anticancer activity for prostate cancer therapeutics

(2017) Liwei Lang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target

(2017) Amadou K. S. Camara et al.   Frontiers in Physiology

Advances in the quantification of mitochondrial function in primary human immune cells through extracellular flux analysis

(2017) Dequina Nicholas et al.   PLoS One

Recurrent De Novo and Biallelic Variation of ATAD3A , Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes

(2016) Tamar Harel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The WASF3-NCKAP1-CYFIP1 Complex Is Essential for Breast Cancer Metastasis

(2016) Y. Teng et al.   CANCER RESEARCH

Mitochondria and Cancer

(2016) Sejal Vyas et al.   CELL

Stapled peptides: providing the best of both worlds in drug development

(2016) Xiayang Xie et al.   Future Medicinal Chemistry

ARF1 promotes prostate tumorigenesis via targeting oncogenic MAPK signaling

(2016) Jason E. Davis et al.   Oncotarget

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Targeting the WASF3-CYFIP1 Complex Using Stapled Peptides Suppresses Cancer Cell Invasion

(2015) Y. Teng et al.   CANCER RESEARCH

Mitochondrial ATAD3A combines with GRP78 to regulate the WASF3 metastasis-promoting protein

(2015) Y Teng et al.   ONCOGENE

The nuclear translocation of ERK1/2 as an anticancer target

(2015) Alexander Plotnikov et al.   Nature Communications

TNF and MAP kinase signalling pathways

(2014) Guadalupe Sabio et al.   SEMINARS IN IMMUNOLOGY

Silencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo

(2014) Tasleem Arif et al.   Molecular Therapy-Nucleic Acids

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

HSP90 and HSP70 Proteins Are Essential for Stabilization and Activation of WASF3 Metastasis-promoting Protein

(2012) Yong Teng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A

(2012) Nicolas Merle et al.   MITOCHONDRION

Identification of a Dynamic Mitochondrial Protein Complex Driving Cholesterol Import, Trafficking, and Metabolism to Steroid Hormones

(2012) Malena B. Rone et al.   MOLECULAR ENDOCRINOLOGY

ERK1/2 Regulation of CD44 Modulates Oral Cancer Aggressiveness

(2011) N. P. Judd et al.   CANCER RESEARCH

Topological analysis of ATAD3A insertion in purified human mitochondria

(2010) Arnaud Hubstenberger et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

ATPase family AAA domain-containing 3A is a novel anti-apoptotic factor in lung adenocarcinoma cells

(2010) H.-Y. Fang et al.   JOURNAL OF CELL SCIENCE

The Calcium-Dependent Interaction between S100B and the Mitochondrial AAA ATPase ATAD3A and the Role of This Complex in the Cytoplasmic Processing of ATAD3A

(2010) Benoît Gilquin et al.   MOLECULAR AND CELLULAR BIOLOGY

The AAA+ ATPase ATAD3A Controls Mitochondrial Dynamics at the Interface of the Inner and Outer Membranes

(2010) B. Gilquin et al.   MOLECULAR AND CELLULAR BIOLOGY

A New Paradigm for MAPK: Structural Interactions of hERK1 with Mitochondria in HeLa Cells

(2009) Soledad Galli et al.   PLoS One