Daphnes Cortex and its licorice-processed products suppress inflammation via the TLR4/NF-κB/NLRP3 signaling pathway and regulation of the metabolic profile in the treatment of rheumatoid arthritis

Tryptophan and indole metabolism in immune regulation

(2021) Alessandra Fiore et al.   CURRENT OPINION IN IMMUNOLOGY

Altered Distribution of Circulating T Follicular Helper-Like Cell Subsets in Rheumatoid Arthritis Patients

(2021) Rui Su et al.   Frontiers in Medicine

Update on the Pathomechanism, Diagnosis, and Treatment Options for Rheumatoid Arthritis

(2020) Yen-Ju Lin et al.   Cells

Cinnamaldehyde suppresses NLRP3 derived IL-1β via activating succinate/HIF-1 in rheumatoid arthritis rats

(2020) Panwang Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Enhanced Keap1-Nrf2/Trx-1 axis by daphnetin protects against oxidative stress-driven hepatotoxicity via inhibiting ASK1/JNK and Txnip/NLRP3 inflammasome activation

(2020) Hongming Lv et al.   PHYTOMEDICINE

Anti-angiogenic effect of Shikonin in rheumatoid arthritis by downregulating PI3K/AKT and MAPKs signaling pathways

(2020) Chunfang Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Exploring the therapeutic promise of targeting HMGB1 in rheumatoid arthritis

(2020) Ishnoor Kaur et al.   LIFE SCIENCES

Hypothesis: Rheumatoid arthritis and periodontitis: A new possible link via prolactin hormone

(2020) Naglaa El-Wakeel et al.   MEDICAL HYPOTHESES

Celastrol ameliorates P. acnes/LPS-induced liver damage and MSU-induced gouty arthritis via inhibiting K63 deubiquitination of NLRP3

(2020) Chang-Yu Yan et al.   PHYTOMEDICINE

Metabolomic and transcriptomic analyses of the anti-rheumatoid arthritis potential of xylopic acid in a bioinspired lipoprotein nanoformulation

(2020) Raphael N. Alolga et al.   BIOMATERIALS

Ginger and turmeric lipid-solubles attenuate heated oil-induced hepatic inflammation via the downregulation of NF-kB in rats

(2020) Mehrdad Zarei et al.   LIFE SCIENCES

Anti-rheumatoid arthritis effects of iridoid glucosides from Lamiophlomis rotata (Benth.) kudo on adjuvant-induced arthritis in rats by OPG/RANKL/NF-κB signaling pathways

(2020) Xiaohui Zhao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Imaging in rheumatoid arthritis: the role of magnetic resonance imaging and computed tomography

(2019) Mikkel Østergaard et al.   Radiologia Medica

Targeted and MMP-2/9 responsive peptides for the treatment of rheumatoid arthritis

(2019) Na Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Effects of daphnetin on the autophagy signaling pathway of fibroblast-like synoviocytes in rats with collagen-induced arthritis (CIA) induced by TNF-α

(2019) Huimin Deng et al.   CYTOKINE

Daphne giraldii Nitsche (Thymelaeaceae): Phytochemistry, pharmacology and medicinal uses

(2019) Shuang Han et al.   PHYTOCHEMISTRY

Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells

(2018) S. Alivernini et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Kaempferol targeting on the fibroblast growth factor receptor 3-ribosomal S6 kinase 2 signaling axis prevents the development of rheumatoid arthritis

(2018) Cheol-Jung Lee et al.   Cell Death & Disease

Hypoxia-induced the upregulation of stromal cell-derived factor 1 in fibroblast-like synoviocytes contributes to migration of monocytes into synovium tissue in rheumatoid arthritis

(2018) Ru Yang et al.   Cell and Bioscience

Collagen-induced arthritis as an animal model of rheumatoid cachexia

(2018) Paulo V.G. Alabarse et al.   Journal of Cachexia Sarcopenia and Muscle

Maresin 1 improves the Treg/Th17 imbalance in rheumatoid arthritis through miR-21

(2018) Shengwei Jin et al.   ANNALS OF THE RHEUMATIC DISEASES

Daphnetin inhibits high glucose-induced extracellular matrix accumulation, oxidative stress and inflammation in human glomerular mesangial cells

(2018) Ke Xu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Anti-ulcer effect and potential mechanism of licoflavone by regulating inflammation mediators and amino acid metabolism

(2017) Yi Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Pathogenetic insights from the treatment of rheumatoid arthritis

(2017) Iain B McInnes et al.   LANCET

P2X7 receptor and NLRP3 inflammasome activation in head and neck cancer

(2017) Ju Young Bae et al.   Oncotarget

Caspase-1 mediated interleukin-18 activation in neutrophils promotes the activity of rheumatoid arthritis in a NLRP3 inflammasome independent manner

(2016) Zhaowen Yang et al.   JOINT BONE SPINE

Enigma of IL-17 and Th17 Cells in Rheumatoid Arthritis and in Autoimmune Animal Models of Arthritis

(2016) Reka Kugyelka et al.   MEDIATORS OF INFLAMMATION

P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation

(2015) KUANG PENG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Daphnetin attenuates microglial activation and proinflammatory factor production via multiple signaling pathways

(2014) Wenwen Yu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

(2014) Lieselotte Vande Walle et al.   NATURE

Changes in toll-like receptor (TLR)4–NFκB–IL1β signaling in male gout patients might be involved in the pathogenesis of primary gouty arthritis

(2013) Yu-Feng Qing et al.   RHEUMATOLOGY INTERNATIONAL

Combined Treatment of Etanercept and MTX Reverses Th1/Th2, Th17/Treg Imbalance in Patients with Rheumatoid Arthritis

(2011) Chen Lina et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Application of metabonomic analytical techniques in the modernization and toxicology research of traditional Chinese medicine

(2009) Yong-Min Lao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Therapeutic effects of daphnetin on adjuvant-induced arthritic rats

(2008) Qin Gao et al.   JOURNAL OF ETHNOPHARMACOLOGY