Saikosaponins and the deglycosylated metabolites exert liver meridian guiding effect through PXR/CYP3A4 inhibition
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Saikosaponins and the deglycosylated metabolites exert liver meridian guiding effect through PXR/CYP3A4 inhibition
Authors
Keywords
Liver targeting, Saikosaponin, Saikogenin, CYP3A4, PXR
Journal
JOURNAL OF ETHNOPHARMACOLOGY
Volume 279, Issue -, Pages 114344
Publisher
Elsevier BV
Online
2021-06-18
DOI
10.1016/j.jep.2021.114344
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Post mortem tissue distribution of quetiapine in forensic autopsies
- (2020) Håvard Breivik et al. FORENSIC SCIENCE INTERNATIONAL
- Polysaccharides of vinegar-baked radix bupleuri promote the hepatic targeting effect of oxymatrine by regulating the protein expression of HNF4α, Mrp2, and OCT1
- (2020) Yayun Wu et al. JOURNAL OF ETHNOPHARMACOLOGY
- Enhancing Curcumin Oral Bioavailability Through Nanoformulations
- (2019) Vinod S. Ipar et al. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
- Freeze-dried Si-Ni-San powder can ameliorate high fat diet-induced non-alcoholic fatty liver disease
- (2019) Feng Zhu et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Pharmacokinetics and oral bioavailability studies of three saikogenins in rats using a validated UFLC-MS/MS method
- (2019) Jingjing Liu et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- In vitro studies on the metabolism of saikogenins and the detection of their metabolites in authentic biosamples
- (2019) Yunwen Xue et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Saikosaponin b2 enhances the hepatotargeting effect of anticancer drugs through inhibition of multidrug resistance-associated drug transporters
- (2019) Ya Zhao et al. LIFE SCIENCES
- Studies on the potential link between antidepressant effect of Xiaoyao San and its pharmacological activity of hepatoprotection based on multi-platform metabolomics
- (2019) Congcong Chen et al. JOURNAL OF ETHNOPHARMACOLOGY
- P-Glycoprotein 1 Affects Chemoactivities of Resveratrol against Human Colorectal Cancer Cells
- (2019) Virginie Aires et al. Nutrients
- Enhanced liver-targeting via coadministration of 10-Hydroxycamptothecin polymeric micelles with vinegar baked Radix Bupleuri
- (2018) Haiyang Wu et al. PHYTOMEDICINE
- A comprehensive review and perspectives on pharmacology and toxicology of saikosaponins
- (2018) Xiaojiaoyang Li et al. PHYTOMEDICINE
- Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters
- (2017) Limin Feng et al. Oncotarget
- The Disposition of Oxymatrine in the Vascularly Perfused Rat Intestine-Liver Preparation and Its Metabolism in Rat Liver Microsomes
- (2016) Li Hua Huang et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A systematic review of the active saikosaponins and extracts isolated from Radix Bupleuri and their applications
- (2016) Bochuan Yuan et al. PHARMACEUTICAL BIOLOGY
- In vitro metabolism study of saikosaponin d and its derivatives in rat liver microsomes
- (2016) Pei Yu et al. XENOBIOTICA
- Adjunctive traditional Chinese medicine therapy improves survival of liver cancer patients
- (2015) Yueh-Hsiang Liao et al. LIVER INTERNATIONAL
- Reductive metabolism of oxymatrine is catalyzed by microsomal CYP3A4
- (2015) Zhongqiu Liu et al. Drug Design Development and Therapy
- Modulatory effects of extracts of vinegar-baked Radix Bupleuri and saikosaponins on the activity of cytochrome P450 enzymesin vitro
- (2014) Tongya Yu et al. XENOBIOTICA
- Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters
- (2012) Yakun Chen et al. BIOCHEMICAL PHARMACOLOGY
- Analysis of saikosaponins in Bupleuri Radix and Caihu-shugan-san using reversed-phase HPLC with pulsed amperometric detection
- (2011) Ha-Jeong Kwon et al. JOURNAL OF SEPARATION SCIENCE
- Metabolic Pathways of the Camptothecin Analog AR-67
- (2010) J. Horn et al. DRUG METABOLISM AND DISPOSITION
- In vitroanti-influenza A H1N1 effect of extract of Bupleuri Radix
- (2010) Su Wen et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Liver targeting effect of vinegar-baked Radix Bupleuri on rhein in rats
- (2010) Rui Zhi Zhao et al. JOURNAL OF ETHNOPHARMACOLOGY
- Identification and determination of the saikosaponins in Radix bupleuri by accelerated solvent extraction combined with rapid-resolution LC-MS
- (2010) Yun-Yun Yang et al. JOURNAL OF SEPARATION SCIENCE
- Study on liver targeting effect of vinegar-baked Radix Bupleuri on resveratrol in mice
- (2009) Ruizhi Zhao et al. JOURNAL OF ETHNOPHARMACOLOGY
- Evaluation of traditional Chinese herbal medicine: Chaihu (Bupleuri Radix) by both high-performance liquid chromatographic and high-performance thin-layer chromatographic fingerprint and chemometric analysis
- (2008) Run-tao Tian et al. JOURNAL OF CHROMATOGRAPHY A
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started