Hypoxia blocks ferroptosis of hepatocellular carcinoma via suppression of METTL14 triggered YTHDF2‐dependent silencing of SLC7A11

R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis

(2021) Ying Qing et al.   MOLECULAR CELL

Tumor-Suppressive Role of microRNA-202-3p in Hepatocellular Carcinoma Through the KDM3A/HOXA1/MEIS3 Pathway

(2021) Yijie Zhang et al.   Frontiers in Cell and Developmental Biology

METTL3/IGF2BP1/CD47 contributes to the sublethal heat treatment induced mesenchymal transition in HCC

(2021) Zhuoyang Fan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Hypoxic Microenvironment of Breast Cancer Cells Promotes Resistance in Radiation Therapy

(2021) Cordell Gilreath et al.   Frontiers in Oncology

Regulation of the Migration of Distinct Dendritic Cell Subsets

(2021) Meng Feng et al.   Frontiers in Cell and Developmental Biology

Molecular Mechanisms Driving mRNA Degradation by m6A Modification

(2020) Yujin Lee et al.   TRENDS IN GENETICS

Ferroptosis: past, present and future

(2020) Jie Li et al.   Cell Death & Disease

HIF1A activates the transcription of lncRNA RAET1K to modulate hypoxia-induced glycolysis in hepatocellular carcinoma cells via miR-100-5p

(2020) Yufan Zhou et al.   Cell Death & Disease

Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth

(2020) Caroline Contat et al.   eLife

The m6A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function

(2020) Lifang Ma et al.   Redox Biology

xCT knockdown in human breast cancer cells delays onset of cancer-induced bone pain

(2019) Robert G Ungard et al.   Molecular Pain

Arsenic trioxide inhibits EMT in hepatocellular carcinoma by promoting lncRNA MEG3 via PKM2

(2019) Zhuoyang Fan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular mechanisms of ferroptosis and its role in cancer therapy

(2019) Tao Xu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

EBV epitranscriptome reprogramming by METTL14 is critical for viral-associated tumorigenesis

(2019) Fengchao Lang et al.   PLoS Pathogens

Carbonic anhydrase 9 confers resistance to ferroptosis/apoptosis in malignant mesothelioma under hypoxia

(2019) Zan Li et al.   Redox Biology

METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing

(2019) Xiaoxiang Chen et al.   MOLECULAR THERAPY

R-Spondin3 promotes the tumor growth of choriocarcinoma JEG-3 cells

(2019) Zhilong Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Arsenic sulfide induces RAG1-dependent DNA damage for cell killing by inhibiting NFATc3 in gastric cancer cells

(2019) Ting Kang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Fumarate hydratase inactivation in hereditary leiomyomatosis and renal cell cancer is synthetic lethal with ferroptosis induction

(2018) Michael J. Kerins et al.   CANCER SCIENCE

Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism

(2018) Ying Yang et al.   CELL RESEARCH

METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m 6 A Modification

(2018) Hengyou Weng et al.   Cell Stem Cell

Hypoxia and tumor angiogenesis in the era of hepatocellular carcinoma transarterial loco-regional treatments

(2018) Mario Petrillo et al.   Future Oncology

Zc3h13 Regulates Nuclear RNA m 6 A Methylation and Mouse Embryonic Stem Cell Self-Renewal

(2018) Jing Wen et al.   MOLECULAR CELL

Guidelines for Diagnosis and Treatment of Primary Liver Cancer in China (2017 Edition)

(2018) Jian Zhou et al.   Liver Cancer

VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

(2018) Yanan Yue et al.   Cell Discovery

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress

(2018) Xiaodong Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cyanobacteria-specific algicidal mechanism of bioinspired naphthoquinone derivative, NQ 2-0

(2018) Heon Woo Lee et al.   Scientific Reports

Overexpression of cysteine-glutamate transporter and CD44 for prediction of recurrence and survival in patients with oral cavity squamous cell carcinoma

(2018) Jae Ryung Lee et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

The Biology of m6A RNA Methylation in Normal and Malignant Hematopoiesis

(2018) Ly P. Vu et al.   Cancer Discovery

Settling the m 6 A debate: methylation of mature mRNA is not dynamic but accelerates turnover

(2017) Nicolle A. Rosa-Mercado et al.   GENES & DEVELOPMENT

Corrigendum: Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex

(2017) Xiang Wang et al.   NATURE

Mechanisms of ferroptosis

(2016) Jennifer Yinuo Cao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma

(2016) Jordi Bruix et al.   GASTROENTEROLOGY

METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulatingN6-methyladenosine-dependent primary MicroRNA processing

(2016) Jin-zhao Ma et al.   HEPATOLOGY

Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases

(2016) Ping Wang et al.   MOLECULAR CELL

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

(2015) Kornelius Schulze et al.   NATURE GENETICS

Mechanical Feedback through E-Cadherin Promotes Direction Sensing during Collective Cell Migration

(2014) Danfeng Cai et al.   CELL

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

(2014) Xiao-Li Ping et al.   CELL RESEARCH

Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

(2014) Schraga Schwartz et al.   Cell Reports

ROS inhibitorN-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors

(2013) Marianna Halasi et al.   BIOCHEMICAL JOURNAL

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Current Strategy for Staging and Treatment: The BCLC Update and Future Prospects

(2010) Alejandro Forner et al.   SEMINARS IN LIVER DISEASE

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY