xCT knockdown in human breast cancer cells delays onset of cancer-induced bone pain

Functional effects of TrkA inhibition on system xC−-mediated glutamate release and cancer-induced bone pain

(2018) Tanya Miladinovic et al.   Molecular Pain

Identification of capsazepine as a novel inhibitor of system xc− and cancer-induced bone pain

(2017) Jennifer Fazzari et al.   Journal of Pain Research

Behavioural Effects of Using Sulfasalazine to Inhibit Glutamate Released by Cancer Cells: A Novel target for Cancer-Induced Depression

(2017) Mina G. Nashed et al.   Scientific Reports

RNA-sequencing profiles hippocampal gene expression in a validated model of cancer-induced depression

(2016) M. G. Nashed et al.   GENES BRAIN AND BEHAVIOR

Differences in electrophysiological properties of functionally identified nociceptive sensory neurons in an animal model of cancer-induced bone pain

(2016) Yong Fang Zhu et al.   Molecular Pain

The cystine/glutamate antiporter system xc− drives breast tumor cell glutamate release and cancer-induced bone pain

(2016) Lauren M. Slosky et al.   PAIN

Chronic Inhibition of STAT3/STAT5 in Treatment-Resistant Human Breast Cancer Cell Subtypes: Convergence on the ROS/SUMO Pathway and Its Effects on xCT Expression and System xc- Activity

(2016) Katja Linher-Melville et al.   PLoS One

Interleukin 1β Regulation of the System xc−Substrate-specific Subunit, xCT, in Primary Mouse Astrocytes Involves the RNA-binding Protein HuR

(2015) Jingxue Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signal transducer and activator of transcription 3 and 5 regulate system Xc- and redox balance in human breast cancer cells

(2015) Katja Linher-Melville et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

SLC7A11 expression is associated with seizures and predicts poor survival in patients with malignant glioma

(2015) Stephanie M. Robert et al.   Science Translational Medicine

Expression of xCT and activity of system x c − are regulated by NRF2 in human breast cancer cells in response to oxidative stress

(2015) Eric Habib et al.   Redox Biology

Incidence of bone metastases and survival after a diagnosis of bone metastases in breast cancer patients

(2014) M. Harries et al.   Cancer Epidemiology

Interleukin-1β genotype and circulating levels in cancer patients: Metastatic status and pain perception

(2014) Ana Oliveira et al.   CLINICAL BIOCHEMISTRY

CSF1 overexpression has pleiotropic effects on microgliain vivo

(2014) Ishani De et al.   GLIA

Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target

(2013) Luika A. Timmerman et al.   CANCER CELL

The small molecule, genistein, increases hepcidin expression in human hepatocytes

(2013) Aileen W. Zhen et al.   HEPATOLOGY

Cancer-induced bone pain: Mechanisms and models

(2013) A.N. Lozano-Ondoua et al.   NEUROSCIENCE LETTERS

Inhibition of breast cancer-cell glutamate release with sulfasalazine limits cancer-induced bone pain

(2013) Robert G. Ungard et al.   PAIN

Symptom clusters of pain, depressed mood, and fatigue in lung cancer: assessing the role of cytokine genes

(2013) Cielito C. Reyes-Gibby et al.   SUPPORTIVE CARE IN CANCER

Brain-derived neurotrophic factor modulates N-methyl-D-aspartate receptor activation in a rat model of cancer-induced bone pain

(2012) Li-Na Wang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Glutamate Signaling in Healthy and Diseased Bone

(2012) Robert W. Cowan et al.   Frontiers in Endocrinology

Establishing a relationship between prolactin and altered fatty acid β-Oxidation via carnitine palmitoyl transferase 1 in breast cancer cells

(2011) Katja Linher-Melville et al.   BMC CANCER

Breast Cancer-Induced Bone Remodeling, Skeletal Pain, and Sprouting of Sensory Nerve Fibers

(2011) Aaron P. Bloom et al.   JOURNAL OF PAIN

PrimerBank: a PCR primer database for quantitative gene expression analysis, 2012 update

(2011) X. Wang et al.   NUCLEIC ACIDS RESEARCH

Preventive or late administration of anti-NGF therapy attenuates tumor-induced nerve sprouting, neuroma formation, and cancer pain

(2011) Juan Miguel Jimenez-Andrade et al.   PAIN

Regulation of System xc−Activity and Expression in Astrocytes by Interleukin-1β

(2010) Nicole A. Jackman et al.   GLIA

Metastatic Behavior of Breast Cancer Subtypes

(2010) Hagen Kennecke et al.   JOURNAL OF CLINICAL ONCOLOGY

Blockade of nerve sprouting and neuroma formation markedly attenuates the development of late stage cancer pain

(2010) W.G. Mantyh et al.   NEUROSCIENCE

Cancer cells release glutamate via the cystine/glutamate antiporter

(2009) Mohit K. Sharma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of Inflammation Gene Polymorphisms on Pain Severity in Lung Cancer Patients

(2009) C. C. Reyes-Gibby et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Cancer cell lines release glutamate into the extracellular environment

(2009) Eric P. Seidlitz et al.   CLINICAL & EXPERIMENTAL METASTASIS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH