Efficacy of marine bioactive compound fucoidan for bone regeneration and implant fixation in sheep

Influence of Fucoidan Extracts from Different Fucus Species on Adult Stem Cells and Molecular Mediators in In Vitro Models for Bone Formation and Vascularization

(2021) Fanlu Wang et al.   Marine Drugs

Enzyme-Assisted Fucoidan Extraction from Brown Macroalgae Fucus distichus subsp. evanescens and Saccharina latissima

(2020) Thuan Thi Nguyen et al.   Marine Drugs

Effect of Enzymatically Extracted Fucoidans on Angiogenesis and Osteogenesis in Primary Cell Culture Systems Mimicking Bone Tissue Environment

(2020) Julia Ohmes et al.   Marine Drugs

Functional Characterization of a New GH107 Endo-α-(1,4)-Fucoidanase from the Marine Bacterium Formosa haliotis

(2020) Marlene Vuillemin et al.   Marine Drugs

Biological Activities of Fucoidan and the Factors Mediating Its Therapeutic Effects: A Review of Recent Studies

(2019) Yu Wang et al.   Marine Drugs

Innovative Biomaterials for Bone Regrowth

(2019) Maria Iaquinta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sulfated polysaccharides from macroalgae for bone tissue regeneration

(2019) Jayachandran Venkatesan et al.   CURRENT PHARMACEUTICAL DESIGN

Bioactive Algal-Derived Polysaccharides: Multi-Functionalization, Therapeutic Potential and Biomedical Applications

(2019) Ida Idayu Muhamad et al.   CURRENT PHARMACEUTICAL DESIGN

Fucoidan Prevents RANKL-Stimulated Osteoclastogenesis and LPS-Induced Inflammatory Bone Loss via Regulation of Akt/GSK3β/PTEN/NFATc1 Signaling Pathway and Calcineurin Activity

(2019) Sheng-Hua Lu et al.   Marine Drugs

Current and Future Concepts for the Treatment of Impaired Fracture Healing

(2019) Carsten W. Schlickewei et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Composition, isolation, purification and biological activities of Sargassum fusiforme polysaccharides: A review

(2019) Rui Zhang et al.   CARBOHYDRATE POLYMERS

Animal models for bone tissue engineering and modelling disease

(2018) Jacqui Anne McGovern et al.   Disease Models & Mechanisms

Development of nanocomposite scaffolds based on biomineralization of N,O-carboxymethyl chitosan/fucoidan conjugates for bone tissue engineering

(2018) Hsien-Tsung Lu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Bioactive Compounds from Marine Organisms: Potential for Bone Growth and Healing

(2018) Matthew Carson et al.   Marine Drugs

Fucoidan-induced osteogenic differentiation promotes angiogenesis by inducing vascular endothelial growth factor secretion and accelerates bone repair

(2017) Beom-Su Kim et al.   Journal of Tissue Engineering and Regenerative Medicine

The efficacy of poly-d,l-lactic acid- and hyaluronic acid-coated bone substitutes on implant fixation in sheep

(2017) Christina M. Andreasen et al.   Journal of Orthopaedic Translation

Autologous bone graft in the treatment of post-traumatic bone defects: a systematic review and meta-analysis

(2016) Matheus Lemos Azi et al.   BMC MUSCULOSKELETAL DISORDERS

Interaction of stem cells with nano hydroxyapatite-fucoidan bionanocomposites for bone tissue regeneration

(2016) Ahn Tae Young et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

3D perfusion bioreactor-activated porous granules on implant fixation and early bone formation in sheep

(2016) Ming Ding et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Low-molecular weight fucoidan inhibits the differentiation of osteoclasts and reduces osteoporosis in ovariectomized rats

(2016) Xin Jin et al.   Molecular Medicine Reports

Assessment of activated porous granules on implant fixation and early bone formation in sheep

(2016) Ming Ding et al.   Journal of Orthopaedic Translation

The in vitro and in vivo effects of the low molecular weight fucoidan on the bone osteogenic differentiation properties

(2015) Pai-An Hwang et al.   CYTOTECHNOLOGY

An automated perfusion bioreactor for the streamlined production of engineered osteogenic grafts

(2015) Ming Ding et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Surgical Revascularization in Structural Orthotopic Bone Allograft Increases Bone Remodeling

(2014) Wouter F. Willems et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Fucoidans: Pro- or antiangiogenic agents?

(2014) N. E. Ustyuzhanina et al.   GLYCOBIOLOGY

Efficacy of a small cell-binding peptide coated hydroxyapatite substitute on bone formation and implant fixation in sheep

(2014) Ming Ding et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

ERG expression in chondrogenic bone and soft tissue tumours

(2014) Wonwoo Shon et al.   JOURNAL OF CLINICAL PATHOLOGY

Bone substitutes in orthopaedic surgery: from basic science to clinical practice

(2014) V. Campana et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Concise Review: Evidence for CD34 as a Common Marker for Diverse Progenitors

(2014) Laura E. Sidney et al.   STEM CELLS

Distribution of Basement Membrane Molecules, Laminin and Collagen Type IV, in Normal and Degenerated Cartilage Tissues

(2014) Casper Bindzus Foldager et al.   Cartilage

The effect of mesenchymal stem cells delivered via hydrogel-based tissue engineered periosteum on bone allograft healing

(2013) Michael D. Hoffman et al.   BIOMATERIALS

Hydroxyapatite-fucoidan nanocomposites for bone tissue engineering

(2013) Hee-Seok Jeong et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Fucoidans from brown seaweeds: an update on structures, extraction techniques and use of enzymes as tools for structural elucidation

(2013) Marcel Tutor Ale et al.   RSC Advances

The effects of a novel-reinforced bone substitute and Colloss®E on bone defect healing in sheep

(2012) Ming Ding et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Glucocorticoids maintain human osteoclasts in the active mode of their resorption cycle

(2010) Kent Søe et al.   JOURNAL OF BONE AND MINERAL RESEARCH