Bioactive Compounds from Marine Organisms: Potential for Bone Growth and Healing

Effect of Calcium Derived from Lithothamnion sp. on Markers of Calcium Metabolism in Premenopausal Women

(2018) John L. Zenk et al.   JOURNAL OF MEDICINAL FOOD

Red algal extracts from Plocamium lyngbyanum and Ceramium secundatum stimulate osteogenic activities in vitro and bone growth in zebrafish larvae

(2018) Matthew A. Carson et al.   Scientific Reports

Fucoidan-induced osteogenic differentiation promotes angiogenesis by inducing vascular endothelial growth factor secretion and accelerates bone repair

(2017) Beom-Su Kim et al.   Journal of Tissue Engineering and Regenerative Medicine

Crude Fucoidan Extracts Impair Angiogenesis in Models Relevant for Bone Regeneration and Osteosarcoma via Reduction of VEGF and SDF-1

(2017) Fanlu Wang et al.   Marine Drugs

Marine green macroalgae: a source of natural compounds with mineralogenic and antioxidant activities

(2016) Gwladys Surget et al.   JOURNAL OF APPLIED PHYCOLOGY

Natural marine sponges for bone tissue engineering: The state of art and future perspectives

(2016) Renata Neves Granito et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research

(2016) Robert A Adler et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoprotective Effects of Polysaccharide-EnrichedHizikia fusiformeProcessing ByproductIn VitroandIn VivoModels

(2016) Yong Tae Jeong et al.   JOURNAL OF MEDICINAL FOOD

Influences of Fucoxanthin on Alveolar Bone Resorption in Induced Periodontitis in Rat Molars

(2016) Oguz Kose et al.   Marine Drugs

Low-molecular weight fucoidan inhibits the differentiation of osteoclasts and reduces osteoporosis in ovariectomized rats

(2016) Xin Jin et al.   Molecular Medicine Reports

Postmenopausal Osteoporosis

(2016) Dennis M. Black et al.   NEW ENGLAND JOURNAL OF MEDICINE

The in vitro and in vivo effects of the low molecular weight fucoidan on the bone osteogenic differentiation properties

(2015) Pai-An Hwang et al.   CYTOTECHNOLOGY

Incorporation of the natural marine multi-mineral dietary supplement Aquamin enhances osteogenesis and improves the mechanical properties of a collagen-based bone graft substitute

(2015) Orlaith Brennan et al.   Journal of the Mechanical Behavior of Biomedical Materials

Bioactive quinone derivatives from the marine brown algaSargassum thunbergiiinduce anti-adipogenic and pro-osteoblastogenic activities

(2015) Jung-Ae Kim et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Floridoside from Laurencia undulata promotes osteogenic differentiation in murine bone marrow mesenchymal cells

(2015) BoMi Ryu et al.   Journal of Functional Foods

Fucoidan, a Sulfated Polysaccharide, Inhibits Osteoclast Differentiation and Function by Modulating RANKL Signaling

(2014) Young Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Amphirionin-4 with Potent Proliferation-Promoting Activity on Bone Marrow Stromal Cells from a Marine Dinoflagellate Amphidinium Species

(2014) Mika Minamida et al.   ORGANIC LETTERS

Amphirionin-5, a novel linear polyketide from a cultured marine dinoflagellate Amphidinium species with a potent cell proliferation-promoting activity

(2014) Mai Akakabe et al.   TETRAHEDRON LETTERS

Sargachromanol G inhibits osteoclastogenesis by suppressing the activation NF-κB and MAPKs in RANKL-induced RAW 264.7 cells

(2013) Weon-Jong Yoon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bioactive compounds from marine mussels and their effects on human health

(2013) Ulrike Grienke et al.   FOOD CHEMISTRY

Beneficial Effect of Abalone Intestine Gastro-Intestinal Digests on Osteoblastic MG-63 Cell Differentiation

(2013) Minh Hong Thi Nguyen et al.   Journal of Aquatic Food Product Technology

A Therapeutic Potential for Marine Skeletal Proteins in Bone Regeneration

(2013) David Green et al.   Marine Drugs

Epidemiology of distal humerus fractures in the elderly

(2013) J.-L. Charissoux et al.   Orthopaedics & Traumatology-Surgery & Research

The Osteogenic Potential of the Marine-Derived Multi-Mineral Formula Aquamin Is Enhanced by the Presence of Vitamin D

(2013) A. Widaa et al.   PHYTOTHERAPY RESEARCH

Water Soluble Bioactives of Nacre Mediate Antioxidant Activity and Osteoblast Differentiation

(2013) Ratna Chaturvedi et al.   PLoS One

Tetrameric peptide purified from hydrolysates of biodiesel byproducts of Nannochloropsis oculata induces osteoblastic differentiation through MAPK and Smad pathway on MG-63 and D1 cells

(2013) Minh Hong Thi Nguyen et al.   PROCESS BIOCHEMISTRY

The In Vitro and In Vivo Effects of a Low-Molecular-Weight Fucoidan on the Osteogenic Capacity of Human Adipose-Derived Stromal Cells

(2013) Jessica Pereira et al.   TISSUE ENGINEERING PART A

Osteoporosis in the European Union: medical management, epidemiology and economic burden

(2013) E. Hernlund et al.   Archives of Osteoporosis

Enhancement of bone regeneration through facile surface functionalization of solid freeform fabrication-based three-dimensional scaffolds using mussel adhesive proteins

(2012) Jung Min Hong et al.   Acta Biomaterialia

The role of nacreous factors in preventing osteoporotic bone loss through both osteoblast activation and osteoclast inactivation

(2012) Hyunsoo Kim et al.   BIOMATERIALS

Phorbaketal A stimulates osteoblast differentiation through TAZ mediated Runx2 activation

(2012) Mi Ran Byun et al.   FEBS LETTERS

Identification of Proteins with Potential Osteogenic Activity Present in the Water-Soluble Matrix Proteins fromCrassostrea gigasNacre Using a Proteomic Approach

(2012) Daniel V. Oliveira et al.   TheScientificWorldJOURNAL

Designs from the deep: Marine organisms for bone tissue engineering

(2011) S.A. Clarke et al.   BIOTECHNOLOGY ADVANCES

Biselyngbyaside, isolated from marine cyanobacteria, inhibits osteoclastogenesis and induces apoptosis in mature osteoclasts

(2011) Takayuki Yonezawa et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Therapies from Fucoidan; Multifunctional Marine Polymers

(2011) Janet Helen Fitton   Marine Drugs

Marine Bioactives as Functional Food Ingredients: Potential to Reduce the Incidence of Chronic Diseases

(2011) Sinéad Lordan et al.   Marine Drugs

The Skeletal Organic Matrix from Mediterranean Coral Balanophyllia europaea Influences Calcium Carbonate Precipitation

(2011) Stefano Goffredo et al.   PLoS One

Pharmacological Modulation of Human Mesenchymal Stem Cell Chondrogenesis by a Chemically Oversulfated Polysaccharide of Marine Origin: Potential Application to Cartilage Regenerative Medicine

(2011) Christophe Merceron et al.   STEM CELLS

In Vitro and In Vivo Osteogenic Activity of Largazole

(2011) Su-Ui Lee et al.   ACS Medicinal Chemistry Letters

Molluscan biological and chemical diversity: secondary metabolites and medicinal resources produced by marine molluscs

(2010) Kirsten Benkendorff   BIOLOGICAL REVIEWS

Mechanism and challenges in commercialisation of algal biofuels

(2010) Anoop Singh et al.   BIORESOURCE TECHNOLOGY

A Mineral-Rich Extract from the Red Marine Algae Lithothamnion calcareum Preserves Bone Structure and Function in Female Mice on a Western-Style Diet

(2010) Muhammad Nadeem Aslam et al.   CALCIFIED TISSUE INTERNATIONAL

REVIEW ARTICLE: Reducing fracture risk with calcium and vitamin D

(2010) Paul Lips et al.   CLINICAL ENDOCRINOLOGY

Pinctada fucata mantle gene 3 (PFMG3) promotes differentiation in mouse osteoblasts (MC3T3-E1)

(2010) Xiaoyan Wang et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Fucoxanthin Induces Apoptosis in Osteoclast-like Cells Differentiated from RAW264.7 Cells

(2010) Swadesh K. Das et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A Marine Mineral Supplement Alters Markers of Bone Metabolism in Yearling Arabians

(2010) Brian D. Nielsen et al.   JOURNAL OF EQUINE VETERINARY SCIENCE

Growth factor delivery-based tissue engineering: general approaches and a review of recent developments

(2010) K. Lee et al.   Journal of the Royal Society Interface

Conventional and Unconventional Antimicrobials from Fish, Marine Invertebrates and Micro-algae

(2010) Valerie J. Smith et al.   Marine Drugs

Rising to the challenge of sustaining coral reef resilience

(2010) Terry P. Hughes et al.   TRENDS IN ECOLOGY & EVOLUTION

Efficacy of Bisphosphonates in Reducing Fracture Risk in Postmenopausal Osteoporosis

(2009) John P. Bilezikian   AMERICAN JOURNAL OF MEDICINE

Evolution of Nacre: Biochemistry and Proteomics of the Shell Organic Matrix of the CephalopodNautilus macromphalus

(2009) Benjamin Marie et al.   CHEMBIOCHEM

Molecular Regulation of Matrix Extracellular Phosphoglycoprotein Expression by Bone Morphogenetic Protein-2

(2009) Young-Dan Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Skeletal protein protection: the mode of action of an anti-osteoporotic marine alkaloid, norzoanthamine

(2009) Masaru Kinugawa et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Ageing populations: the challenges ahead

(2009) Kaare Christensen et al.   LANCET

A natural seaweed derived mineral supplement (Aquamin F) for knee osteoarthritis: A randomised, placebo controlled pilot study

(2009) Joy L Frestedt et al.   Nutrition Journal

Potential effects of a low-molecular-weight fucoidan extracted from brown algae on bone biomaterial osteoconductive properties

(2008) S. Igondjo Tchen Changotade et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Effect of Sargassum horneri Extract on Circulating Bone Metabolic Markers: Supplemental Intake Has an Effect in Healthy Humans

(2008) Toru Matsumoto et al.   JOURNAL OF HEALTH SCIENCE

Specific Expression of BMP2/4 Ortholog in Biomineralizing Tissues of Corals and Action on Mouse BMP Receptor

(2008) Didier Zoccola et al.   MARINE BIOTECHNOLOGY

A natural mineral supplement provides relief from knee osteoarthritis symptoms: a randomized controlled pilot trial

(2008) Joy L Frestedt et al.   Nutrition Journal

FRAX™ and the assessment of fracture probability in men and women from the UK

(2008) J. A. Kanis et al.   OSTEOPOROSIS INTERNATIONAL

Biomaterial effects in articular cartilage tissue engineering using polyglycolic acid, a novel marine origin biomaterial, IGF-I, and TGF-β1

(2008) B B DiCarlo et al.   PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE

Low molecular weight molecules of oyster nacre induce mineralization of the MC3T3-E1 cells

(2007) Marthe Rousseau et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A