Zearalenone Induces Dopaminergic Neurodegeneration via DRP-1-Involved Mitochondrial Fragmentation and Apoptosis in a Caenorhabditis elegans Parkinson’s Disease Model

Occurrence, Impact on Agriculture, Human Health, and Management Strategies of Zearalenone in Food and Feed: A Review

(2021) Dipendra Kumar Mahato et al.   Toxins

Zearalenone Induces Endothelial Cell Apoptosis through Activation of a Cytosolic Ca2+/ERK1/2/p53/Caspase 3 Signaling Pathway

(2021) Hyeon-Ju Lee et al.   Toxins

Distinct fission signatures predict mitochondrial degradation or biogenesis

(2021) Tatjana Kleele et al.   NATURE

Chronic exposure of zearalenone inhibits antioxidant defense and results in aging-related defects associated with DAF-16/FOXO in Caenorhabditis elegans

(2021) Chi-Wei Huang et al.   ENVIRONMENTAL POLLUTION

Oral subchronic exposure to the mycotoxin ochratoxin A induces key pathological features of Parkinson's disease in mice six months after the end of the treatment

(2021) María Izco et al.   FOOD AND CHEMICAL TOXICOLOGY

Nickel-Induced Developmental Neurotoxicity in C. elegans Includes Cholinergic, Dopaminergic and GABAergic Degeneration, Altered Behaviour, and Increased SKN-1 Activity

(2020) Omamuyovwi M. Ijomone et al.   NEUROTOXICITY RESEARCH

Selenium Protects against Zearalenone-Induced Oxidative Stress and Apoptosis in the Mouse Kidney by Inhibiting Endoplasmic Reticulum Stress

(2020) Yi Zhang et al.   Oxidative Medicine and Cellular Longevity

Zearalenone (ZEN) in Livestock and Poultry: Dose, Toxicokinetics, Toxicity and Estrogenicity

(2020) Jundi Liu et al.   Toxins

Zearalenone induces apoptosis of rat Sertoli cells through Fas-Fas ligand and mitochondrial pathway

(2019) Guodong Cai et al.   ENVIRONMENTAL TOXICOLOGY

The role of DRP1 in ropivacaine-induced mitochondrial dysfunction and neurotoxicity

(2019) Yan Chen et al.   Artificial Cells Nanomedicine and Biotechnology

Swimming Induced Paralysis to Assess Dopamine Signaling in Caenorhabditis elegans

(2019) Sirisha Kudumala et al.   Jove-Journal of Visualized Experiments

Global Mycotoxin Occurrence in Feed: A Ten-Year Survey

(2019) Christiane Gruber-Dorninger et al.   Toxins

T-2 toxin neurotoxicity: role of oxidative stress and mitochondrial dysfunction

(2019) Chongshan Dai et al.   ARCHIVES OF TOXICOLOGY

Worldwide contamination of food-crops with mycotoxins: Validity of the widely cited ‘FAO estimate’ of 25%

(2019) Mari Eskola et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Occurrence and toxicity of a fusarium mycotoxin, zearalenone

(2019) Ankita Rai et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Zearalenone induced embryo and neurotoxicity in zebrafish model ( Danio rerio ): Role of oxidative stress revealed by a multi biomarker study

(2018) Sellamani Muthulakshmi et al.   CHEMOSPHERE

Toxic effects of zearalenone on gametogenesis and embryonic development: A molecular point of review

(2018) Dacheng Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

Zearalenone regulates endometrial stromal cell apoptosis and migration via the promotion of mitochondrial fission by activation of the JNK/Drp1 pathway

(2018) Huixiang Wang et al.   Molecular Medicine Reports

Blockade and reversal of swimming-induced paralysis in C. elegans by the antipsychotic and D2-type dopamine receptor antagonist azaperone

(2018) Osama Refai et al.   NEUROCHEMISTRY INTERNATIONAL

Gene-by-environment interactions that disrupt mitochondrial homeostasis cause neurodegeneration in C. elegans Parkinson’s models

(2018) Hanna Kim et al.   Cell Death & Disease

Recent Advances in Biomarkers for Parkinson’s Disease

(2018) Runcheng He et al.   Frontiers in Aging Neuroscience

Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models

(2017) Malabika Maulik et al.   Frontiers in Genetics

Motor symptoms in Parkinson’s disease: A unified framework

(2016) Ahmed A. Moustafa et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Null allele mutants of trt-1 , the catalytic subunit of telomerase in Caenorhabditis elegans , are less sensitive to Mn-induced toxicity and DAergic degeneration

(2016) Omamuyovwi M. Ijomone et al.   NEUROTOXICOLOGY

Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson’s disease model induced by MPTP

(2016) Emily Filichia et al.   Scientific Reports

Zearalenone induced toxicity in SHSY-5Y cells: The role of oxidative stress evidenced by N-acetyl cysteine

(2014) M. Venkataramana et al.   FOOD AND CHEMICAL TOXICOLOGY

Longevity Manipulations Differentially Affect Serotonin/Dopamine Level and Behavioral Deterioration in Aging Caenorhabditis elegans

(2014) J.-A. Yin et al.   JOURNAL OF NEUROSCIENCE

Evaluation and identification of reliable reference genes for toxicological study in Caenorhabditis elegans

(2014) Hongmei Wu et al.   MOLECULAR BIOLOGY REPORTS

The prevalence of Parkinson's disease: A systematic review and meta-analysis

(2014) Tamara Pringsheim et al.   MOVEMENT DISORDERS

n-Butylidenephthalide Protects against Dopaminergic Neuron Degeneration and α-Synuclein Accumulation in Caenorhabditis elegans Models of Parkinson's Disease

(2014) Ru-Huei Fu et al.   PLoS One

Zearalenone induces apoptosis and cytoprotective autophagy in primary Leydig cells

(2014) Yajun Wang et al.   TOXICOLOGY LETTERS

Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo

(2014) Phillip M. Rappold et al.   Nature Communications

Modeling neurodegenerative diseases in Caenorhabditis elegans

(2013) Jia Li et al.   EXPERIMENTAL NEUROLOGY

Fungal-derived semiochemical 1-octen-3-ol disrupts dopamine packaging and causes neurodegeneration

(2013) A. A. Inamdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of mitochondria in apoptosis

(2011) Seon-Yong Jeong et al.   BMB Reports

Mechanisms of Mycotoxin-Induced Neurotoxicity through Oxidative Stress-Associated Pathways

(2011) Kunio Doi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Zearalenone induces apoptosis and necrosis in porcine granulosa cells via a caspase-3- and caspase-9-dependent mitochondrial signaling pathway

(2011) Li Zhu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mycotoxin zearalenone induces AIF- and ROS-mediated cell death through p53- and MAPK-dependent signaling pathways in RAW264.7 macrophages

(2011) Ji-Yeon Yu et al.   TOXICOLOGY IN VITRO

Ageing, neurodegeneration and Parkinson's disease

(2010) J. V. Hindle   AGE AND AGEING

C. elegansas a model organism to investigate molecular pathways involved with Parkinson's disease

(2010) Adam J. Harrington et al.   DEVELOPMENTAL DYNAMICS

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease

(2010) Chen Yao et al.   NEUROBIOLOGY OF DISEASE

Differential Regulation of Dopamine Transporter Function and Location by Low Concentrations of Environmental Estrogens and 17β-Estradiol

(2009) Rebecca A. Alyea et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C. elegans

(2008) David Hoogewijs et al.   BMC MOLECULAR BIOLOGY

Mitochondrial fragmentation in neurodegeneration

(2008) Andrew B. Knott et al.   NATURE REVIEWS NEUROSCIENCE

The mycotoxin Zearalenone induces apoptosis in human hepatocytes (HepG2) via p53-dependent mitochondrial signaling pathway

(2008) Imen Ayed-Boussema et al.   TOXICOLOGY IN VITRO