Transcriptome Analysis of Insulin Signaling-Associated Transcription Factors in C. elegans Reveal Their Genome-Wide Target Genes Specificity and Complexity

HSB-1 Inhibition and HSF-1 Overexpression Trigger Overlapping Transcriptional Changes to Promote Longevity in Caenorhabditis elegans

(2019) Surojit Sural et al.   G3-Genes Genomes Genetics

The genome-wide role of HSF-1 in the regulation of gene expression in Caenorhabditis elegans

(2016) Jessica Brunquell et al.   BMC GENOMICS

E2F coregulates an essential HSF developmental program that is distinct from the heat-shock response

(2016) Jian Li et al.   GENES & DEVELOPMENT

FOXO/DAF-16 Activation Slows Down Turnover of the Majority of Proteins in C. elegans

(2016) Ineke Dhondt et al.   Cell Reports

Direct link between metabolic regulation and the heat-shock response through the transcriptional regulator PGC-1α

(2015) Neri Minsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing

(2015) Johannes Mansfeld et al.   Nature Communications

Genome-wide endogenous DAF-16/FOXO recruitment dynamics during lowered insulin signalling in C. elegans

(2015) Neeraj Kumar et al.   Oncotarget

Heterotypic Signals from Neural HSF-1 Separate Thermotolerance from Longevity

(2015) Peter M. Douglas et al.   Cell Reports

Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity

(2014) Collin Y. Ewald et al.   NATURE

Heat shock factor 1 mediates the longevity conferred by inhibition of TOR and insulin/IGF-1 signaling pathways inC. elegans

(2013) Keunhee Seo et al.   AGING CELL

DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity

(2013) Christian G. Riedel et al.   NATURE CELL BIOLOGY

Caenorhabditis elegansHSF-1 is an essential nuclear protein that forms stress granule-like structures following heat shock

(2012) Elizabeth A. Morton et al.   AGING CELL

Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging

(2012) János Barna et al.   BMC DEVELOPMENTAL BIOLOGY

HSF-1 Regulators DDL-1/2 Link Insulin-like Signaling to Heat-Shock Responses and Modulation of Longevity

(2012) Wei-Chung Chiang et al.   CELL

A Role for SKN-1/Nrf in Pathogen Resistance and Immunosenescence in Caenorhabditis elegans

(2012) Diána Papp et al.   PLoS Pathogens

Specific SKN-1/Nrf Stress Responses to Perturbations in Translation Elongation and Proteasome Activity

(2011) Xuan Li et al.   PLoS Genetics

Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans

(2010) W. Niu et al.   GENOME RESEARCH

DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO

(2010) Eugene Schuster et al.   Molecular Systems Biology

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

RNAi Screening Implicates a SKN-1–Dependent Transcriptional Response in Stress Resistance and Longevity Deriving from Translation Inhibition

(2010) Jinling Wang et al.   PLoS Genetics

Condition-adapted stress and longevity gene regulation byCaenorhabditis elegansSKN-1/Nrf

(2009) Riva P. Oliveira et al.   AGING CELL

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans

(2008) Katherine A. Steinkraus et al.   AGING CELL

Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans

(2008) Jennifer M.A. Tullet et al.   CELL

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Proteasomal dysfunction activates the transcription factor SKN-1 and produces a selective oxidative-stress response inCaenorhabditis elegans

(2007) Nate W. Kahn et al.   BIOCHEMICAL JOURNAL