Reduced Endothelial Leptin Signaling Increases Vascular Adrenergic Reactivity in a Mouse Model of Congenital Generalized Lipodystrophy

Selective deficiency in endothelial PTP1B protects from diabetes and endoplasmic reticulum stress-associated endothelial dysfunction via preventing endothelial cell apoptosis

(2020) Samuel Legeay et al.   BIOMEDICINE & PHARMACOTHERAPY

2020 International Society of Hypertension Global Hypertension Practice Guidelines

(2020) Thomas Unger et al.   HYPERTENSION

Greater α1-adrenergic-mediated vasoconstriction in contracting skeletal muscle of patients with type 2 diabetes

(2020) Joshua M. Bock et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

HIV Protease Inhibitor Ritonavir Impairs Endothelial Function Via Reduction in Adipose Mass and Endothelial Leptin Receptor‐Dependent Increases in NADPH Oxidase 1 (Nox1), C‐C Chemokine Receptor Type 5 (CCR5), and Inflammation

(2020) Thiago Bruder‐Nascimento et al.   Journal of the American Heart Association

High-Fat Diet-Induced Obesity Model Does Not Promote Endothelial Dysfunction via Increasing Leptin/Akt/eNOS Signaling

(2019) Vanessa da Silva Rocha et al.   Frontiers in Physiology

Hyperglycemia Enhances Constriction of Retinal Venules via Activation of the Reverse-Mode Sodium-Calcium Exchanger

(2019) Yen-Lin Chen et al.   DIABETES

Leptin Restores Endothelial Function via Endothelial PPARγ-Nox1–Mediated Mechanisms in a Mouse Model of Congenital Generalized Lipodystrophy

(2019) Thiago Bruder-Nascimento et al.   HYPERTENSION

Nonalcoholic Fatty Liver Disease

(2019) Yan-Ci Zhao et al.   HYPERTENSION

The regulation of aldosterone secretion by leptin

(2018) Jessica L. Faulkner et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Renal injury in Seipin-deficient lipodystrophic mice and its reversal by adipose tissue transplantation or leptin administration alone: adipose tissue–kidney crosstalk

(2018) Xue-Jing Liu et al.   FASEB JOURNAL

Ptp1b deletion in pro-opiomelanocortin neurons increases energy expenditure and impairs endothelial function via TNF-  dependent mechanisms

(2016) T. Bruder-Nascimento et al.   CLINICAL SCIENCE

Adipocyte (Pro)Renin-Receptor Deficiency Induces Lipodystrophy, Liver Steatosis and Increases Blood Pressure in Male MiceNovelty and Significance

(2016) Chia-Hua Wu et al.   HYPERTENSION

Leptin Does Not Mediate Hypertension Associated With Human Obesity

(2015) Rebecca J. Brown et al.   CELL

Vascular injury in diabetic db/db mice is ameliorated by atorvastatin: role of Rac1/2-sensitive Nox-dependent pathways

(2015) Thiago Bruder-Nascimento et al.   CLINICAL SCIENCE

Arterial Stiffness and Incidence of Systolic Hypertension: The End to the “Chicken-Egg” Question?

(2015) Athanase D. Protogerou et al.   Journal of Clinical Hypertension

Deletion of protein tyrosine phosphatase 1b in proopiomelanocortin neurons reduces neurogenic control of blood pressure and protects mice from leptin- and sympatho-mediated hypertension

(2015) Thiago Bruder-Nascimento et al.   PHARMACOLOGICAL RESEARCH

Spironolactone treatment attenuates vascular dysfunction in type 2 diabetic mice by decreasing oxidative stress and restoring NO/GC signaling

(2015) Marcondes A. B. Silva et al.   Frontiers in Physiology

Arterial Stiffness and Hypertension

(2014) Gary F. Mitchell   HYPERTENSION

Contractile protein expression is upregulated by reactive oxygen species in aorta of Goto-Kakizaki rat

(2013) Sukrutha Chettimada et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Peroxisome Proliferator-Activated Receptor-γ Mutations Responsible for Lipodystrophy With Severe Hypertension Activate the Cellular Renin–Angiotensin System

(2013) Martine Auclair et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Leptin receptor deficient diabetic (db/db) mice are compromised in postnatal bone regeneration

(2013) Tamás Rőszer et al.   CELL AND TISSUE RESEARCH

Leptin Potentiates Endothelium-Dependent Relaxation by Inducing Endothelial Expression of Neuronal NO Synthase

(2012) Sebastian Benkhoff et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is a Cell-Autonomous Regulator of Lipolysis Essential for Adipocyte Differentiation

(2012) W. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Vascular adaptive responses to physical exercise and to stress are affected differently by nandrolone administration

(2011) T. Bruder-Nascimento et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Impact of Leptin-Mediated Sympatho-Activation on Cardiovascular Function in Obese Mice

(2011) Eric J. Belin de Chantemèle et al.   HYPERTENSION

Rationale for Leptin-Replacement Therapy for Severe Lipodystrophy

(2010) Elif Oral et al.   Endocrine Practice

Role of Leptin in the Activation of Immune Cells

(2010) Patricia Fernández-Riejos et al.   MEDIATORS OF INFLAMMATION

Cardiomyopathy in Congenital and Acquired Generalized Lipodystrophy

(2010) Beatrice C. Lupsa et al.   MEDICINE

Protein Tyrosine Phosphatase 1B, a Major Regulator of Leptin-Mediated Control of Cardiovascular Function

(2009) Eric J. Belin de Chantemèle et al.   CIRCULATION