Psoriasiform Inflammation Is Associated with Mitochondrial Fission/GDAP1L1 Signaling in Macrophages

Immune responses and therapeutic options in psoriasis

(2021) Inna S. Afonina et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mitochondrial dynamics in health and disease

(2021) Nethmi M.B. Yapa et al.   FEBS LETTERS

2,4-Dimethoxy-6-Methylbenzene-1,3-diol, a Benzenoid From Antrodia cinnamomea, Mitigates Psoriasiform Inflammation by Suppressing MAPK/NF-κB Phosphorylation and GDAP1L1/Drp1 Translocation

(2021) Shih-Yi Chuang et al.   Frontiers in Immunology

S1PR4‐dependent CCL2 production promotes macrophage recruitment in a murine psoriasis model

(2020) Christian Schuster et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Review—Current Concepts in Inflammatory Skin Diseases Evolved by Transcriptome Analysis: In-Depth Analysis of Atopic Dermatitis and Psoriasis

(2020) Julius Schwingen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial fission and fusion: A dynamic role in aging and potential target for age-related disease

(2020) Yasmine J. Liu et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The cell biology of mitochondrial membrane dynamics

(2020) Marta Giacomello et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

IL-24: A new player in the pathogenesis of pro-inflammatory and allergic skin diseases

(2020) Yasutaka Mitamura et al.   ALLERGOLOGY INTERNATIONAL

Redox Modifications of Proteins of the Mitochondrial Fusion and Fission Machinery

(2020) Christina Wolf et al.   Cells

Role of regulatory T cells in psoriasis pathogenesis and treatment

(2020) L. Nussbaum et al.   BRITISH JOURNAL OF DERMATOLOGY

Induction of Regulatory T Cells and Correction of Cytokine Disbalance by Short-Chain Fatty Acids: Implications for Psoriasis Therapy

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Advanced Characterization of Imiquimod-Induced Psoriasis-Like Mouse Model

(2020) Mehwish Jabeen et al.   Pharmaceutics

Regulatory cells in the skin: pathophysiological role and potential targets for anti-inflammatory therapies

(2019) Sagar Uttarkar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Risk Factors for the Development of Psoriasis

(2019) Koji Kamiya et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cutaneous delivery of [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol, an indole-3-carbinol derivative, mitigates psoriasiform lesion by blocking MAPK/NF-κB/AP-1 activation

(2019) Jing-Ru Weng et al.   BIOMEDICINE & PHARMACOTHERAPY

Murine models of psoriasis and their usefulness for drug discovery

(2018) Shih-Yi Chuang et al.   Expert Opinion on Drug Discovery

MAPK Phosphatase-1 Deficiency Exacerbates the Severity of Imiquimod-Induced Psoriasiform Skin Disease

(2018) Weiheng Zhao et al.   Frontiers in Immunology

The Interplay Between Keratinocytes and Immune Cells in the Pathogenesis of Psoriasis

(2018) Cristina Albanesi et al.   Frontiers in Immunology

Psoriasis: Keratinocytes or Immune Cells – Which Is the Trigger?

(2018) Farida Benhadou et al.   DERMATOLOGY

Mitochondrial dysfunction in affected skin and increased mitochondrial DNA in serum from patients with psoriasis

(2018) Anastasia Therianou et al.   EXPERIMENTAL DERMATOLOGY

The Role of Toll-Like Receptors in the Production of Cytokines by Human Lung Macrophages

(2018) Stanislas Grassin-Delyle et al.   Journal of Innate Immunity

Chrysophanol suppresses pro-inflammatory response in microglia via regulation of Drp1-dependent mitochondrial fission

(2017) Unbin Chae et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Clinically resolved psoriatic lesions contain psoriasis-specific IL-17–producing αβ T cell clones

(2017) Tiago R. Matos et al.   JOURNAL OF CLINICAL INVESTIGATION

Psoriasis and comorbid diseases

(2017) Junko Takeshita et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Keratinocyte-Derived IL-17E Contributes to Inflammation in Psoriasis

(2016) Luisa Senra et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cross-Disease Transcriptomics: Unique IL-17A Signaling in Psoriasis Lesions and an Autoimmune PBMC Signature

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A systematic review of worldwide epidemiology of psoriasis

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Paeoniflorin inhibits skin lesions in imiquimod-induced psoriasis-like mice by downregulating inflammation

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Psoriasis

(2015) Wolf-Henning Boehncke et al.   LANCET

Inhibition of CCR7/CCL19 Axis in Lesional Skin Is a Critical Event for Clinical Remission Induced by TNF Blockade in Patients with Psoriasis

(2013) Francesca Bosè et al.   AMERICAN JOURNAL OF PATHOLOGY

IL-17A Induces Pro-Inflammatory Cytokines Production in Macrophages via MAPKinases, NF-κB and AP-1

(2013) Jian Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

TLRs to cytokines: Mechanistic insights from the imiquimod mouse model of psoriasis

(2013) Barry Flutter et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tumor Necrosis Factor Receptor Signaling in Keratinocytes Triggers Interleukin-24-Dependent Psoriasis-like Skin Inflammation in Mice

(2013) Snehlata Kumari et al.   IMMUNITY

Mitochondrial dynamics modulate the expression of pro-inflammatory mediators in microglial cells

(2013) Junghyung Park et al.   JOURNAL OF NEUROCHEMISTRY

TLR-induced PAI-2 expression suppresses IL-1  processing via increasing autophagy and NLRP3 degradation

(2013) S.-Y. Chuang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Mitochondrial Fission and Fusion

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Rise in dermal CD11c+ dendritic cells associates with early-stage development of psoriatic lesions

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Human mast cell degranulation and preformed TNF secretion require mitochondrial translocation to exocytosis sites: Relevance to atopic dermatitis

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Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Increased expression of IL-12p70 and IL-23 by multiple dendritic cell and macrophage subsets in plaque psoriasis

(2009) Nikhil Yawalkar et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance

(2009) Axel Niemann et al.   NEUROBIOLOGY OF DISEASE