Chrysophanol suppresses pro-inflammatory response in microglia via regulation of Drp1-dependent mitochondrial fission

Neuroprotective effects of Chrysophanol against inflammation in middle cerebral artery occlusion mice

(2016) Yongmei Zhao et al.   NEUROSCIENCE LETTERS

Chrysophanol Inhibits NALP3 Inflammasome Activation and Ameliorates Cerebral Ischemia/Reperfusion in Mice

(2014) Nan Zhang et al.   MEDIATORS OF INFLAMMATION

Chrysophanol attenuates lead exposure-induced injury to hippocampal neurons in neonatal mice

(2014) Shu Wang et al.   Neural Regeneration Research

Mitochondrial dynamics modulate the expression of pro-inflammatory mediators in microglial cells

(2013) Junghyung Park et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial Fission Triggered by Hyperglycemia Is Mediated by ROCK1 Activation in Podocytes and Endothelial Cells

(2012) Wenjian Wang et al.   Cell Metabolism

Natural products as a rich source of tau-targeting drugs for Alzheimer’s disease

(2012) Laurent Calcul et al.   Future Medicinal Chemistry

Rapid and efficient purification of chrysophanol in Rheum Palmatum LINN by supercritical fluid extraction coupled with preparative liquid chromatography in tandem

(2012) Tiffany Chien-Ting Lo et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins

(2011) Shengnan Wu et al.   FEBS Journal

PKA/AKAP1 and PP2A/B 2 Regulate Neuronal Morphogenesis via Drp1 Phosphorylation and Mitochondrial Bioenergetics

(2011) A. S. Dickey et al.   JOURNAL OF NEUROSCIENCE

Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1

(2010) Chuang-Rung Chang et al.   Annals of the New York Academy of Sciences

Regulation of mitochondrial biogenesis

(2010) François R. Jornayvaz et al.   Essays in Biochemistry

Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells

(2010) Chi-Cheng Lu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease

(2009) Tuan Hoang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Real-time in vivo bioluminescence imaging of lentiviral vector–mediated gene transfer in mouse testis

(2009) T.S. Kim et al.   THERIOGENOLOGY

CaM kinase Iα–induced phosphorylation of Drp1 regulates mitochondrial morphology

(2008) Xiao-Jian Han et al.   JOURNAL OF CELL BIOLOGY

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

(2008) G. M. Cereghetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA