Aristolochic Acid Induces Renal Fibrosis and Senescence in Mice

Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders

(2021) Yoshikazu Johmura et al.   SCIENCE

Tissue-specific expression of the SARS-CoV-2 receptor, angiotensin-converting enzyme 2, in mouse models of chronic kidney disease

(2021) Shunichiro Tsukamoto et al.   Scientific Reports

Effects of rikkunshito on renal fibrosis and inflammation in angiotensin II-infused mice

(2019) Kengo Azushima et al.   Scientific Reports

Angiotensin II Type 1 Receptor-associated Protein Inhibits Angiotensin II-induced Insulin Resistance with Suppression of Oxidative Stress in Skeletal Muscle Tissue

(2018) Kohji Ohki et al.   Scientific Reports

An Integrated View of Aristolochic Acid Nephropathy: Update of the Literature

(2017) Inès Jadot et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adipocyte‐Specific Enhancement of Angiotensin II Type 1 Receptor‐Associated Protein Ameliorates Diet‐Induced Visceral Obesity and Insulin Resistance

(2017) Kengo Azushima et al.   Journal of the American Heart Association

Mitochondria are required for pro‐ageing features of the senescent phenotype

(2016) Clara Correia‐Melo et al.   EMBO JOURNAL

Renal Aging: Causes and Consequences

(2016) Eoin D. O’Sullivan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Mitochondrial Basis of Aging

(2016) Nuo Sun et al.   MOLECULAR CELL

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

Prevalence of reduced kidney function and albuminuria in older adults: the Berlin Initiative Study

(2016) Natalie Ebert et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Protective effect of nitric oxide in aristolochic acid-induced toxic acute kidney injury: an old friend with new assets

(2015) Anne-Émilie Declèves et al.   EXPERIMENTAL PHYSIOLOGY

Axonal regeneration through the fibrous scar in lesioned goldfish spinal cord

(2015) A. Takeda et al.   NEUROSCIENCE

Ablation of the p16INK4a tumour suppressor reverses ageing phenotypes of klotho mice

(2015) Seidai Sato et al.   Nature Communications

Aristolochic Acid Nephropathy: Epidemiology, Clinical Presentation, and Treatment

(2014) Randy L. Luciano et al.   DRUG SAFETY

Deletion of the angiotensin II type 1 receptor–associated protein enhances renal sodium reabsorption and exacerbates angiotensin II–mediated hypertension

(2014) Masato Ohsawa et al.   KIDNEY INTERNATIONAL

Enhanced Angiotensin Receptor-Associated Protein in Renal Tubule Suppresses Angiotensin-Dependent Hypertension

(2013) Hiromichi Wakui et al.   HYPERTENSION

The mouse as a model organism in aging research: Usefulness, pitfalls and possibilities

(2012) Valerie Vanhooren et al.   AGEING RESEARCH REVIEWS

Aging-related kidney damage is associated with a decrease in klotho expression and an increase in superoxide production

(2010) Zhong Zuo et al.   AGE

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

(2010) Shinji Kume et al.   JOURNAL OF CLINICAL INVESTIGATION

Feedback between p21 and reactive oxygen production is necessary for cell senescence

(2010) João F Passos et al.   Molecular Systems Biology

Klotho as a regulator of oxidative stress and senescence

(2008) Makoto Kuro-o   BIOLOGICAL CHEMISTRY

Effect of Olmesartan on Tissue Expression Balance Between Angiotensin II Receptor and Its Inhibitory Binding Molecule

(2008) Atsu-ichiro Shigenaga et al.   HYPERTENSION