Chronic Exposure to HIV-Derived Protein Tat Impairs Endothelial Function via Indirect Alteration in Fat Mass and Nox1-Mediated Mechanisms in Mice

HIV Protease Inhibitor Ritonavir Impairs Endothelial Function Via Reduction in Adipose Mass and Endothelial Leptin Receptor‐Dependent Increases in NADPH Oxidase 1 (Nox1), C‐C Chemokine Receptor Type 5 (CCR5), and Inflammation

(2020) Thiago Bruder‐Nascimento et al.   Journal of the American Heart Association

Effect of changes in body mass index on the risk of cardiovascular disease and diabetes mellitus in HIV-positive individuals

(2020) Kathy Petoumenos et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Impact of HIV/SIV infection and viral proteins on adipose tissue fibrosis and adipogenesis

(2019) Jennifer Gorwood et al.   AIDS

Twenty Years Of Antiretroviral Therapy For People Living With HIV: Global Costs, Health Achievements, Economic Benefits

(2019) Steven S. Forsythe et al.   HEALTH AFFAIRS

Progesterone Predisposes Females to Obesity-Associated Leptin-Mediated Endothelial Dysfunction via Upregulating Endothelial MR (Mineralocorticoid Receptor) Expression

(2019) Jessica L. Faulkner et al.   HYPERTENSION

HIV infection and coronary heart disease: mechanisms and management

(2019) Priscilla Y. Hsue et al.   Nature Reviews Cardiology

HIV Infection and Incidence of Cardiovascular Diseases: An Analysis of a Large Healthcare Database

(2019) Alvaro Alonso et al.   Journal of the American Heart Association

Leptin Restores Endothelial Function via Endothelial PPARγ-Nox1–Mediated Mechanisms in a Mouse Model of Congenital Generalized Lipodystrophy

(2019) Thiago Bruder-Nascimento et al.   HYPERTENSION

Global Burden of Atherosclerotic Cardiovascular Disease in People Living with the Human Immunodeficiency Virus: A Systematic Review and Meta-Analysis

(2018) Anoop S. V. Shah et al.   CIRCULATION

The role of HIV Tat protein in HIV-related cardiovascular diseases

(2018) Yanan Jiang et al.   Journal of Translational Medicine

Risk factors associated with overweight and obesity in HIV-infected people

(2018) Véronique Obry-Roguet et al.   MEDICINE

HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production

(2018) Rawan El-Amine et al.   Redox Biology

Vascular endothelial dysfunction in the wake of HIV and ART

(2018) Clara Marincowitz et al.   FEBS Journal

Lipodystrophies, dyslipidaemias and atherosclerotic cardiovascular disease

(2018) Iram Hussain et al.   PATHOLOGY

HIV-1–Associated Atherosclerosis

(2017) Alison Kearns et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Crosstalk between HDAC6 and Nox2-based NADPH oxidase mediates HIV-1 Tat-induced pro-inflammatory responses in astrocytes

(2017) Gi Soo Youn et al.   Redox Biology

Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging

(2017) Alex M. Dickens et al.   Scientific Reports

Influence of HIV infection and the use of antiretroviral therapy on selenium and selenomethionine concentrations and antioxidant protection

(2016) Lígia Moriguchi Watanabe et al.   NUTRITION

The metabolic and cardiovascular consequences of obesity in persons with HIV on long-term antiretroviral therapy

(2015) John R. Koethe et al.   AIDS

Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac FibrosisCLINICAL PERSPECTIVE

(2015) Anne-Cécile Huby et al.   CIRCULATION

The Roles of HIV-1 Proteins and Antiretroviral Drug Therapy in HIV-1-Associated Endothelial Dysfunction

(2015) Erik R. Kline et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Associations Between HIV Infection and Subclinical Coronary Atherosclerosis

(2014) Wendy S. Post et al.   ANNALS OF INTERNAL MEDICINE

The Vascular Endothelium and Human Diseases

(2014) Peramaiyan Rajendran et al.   International Journal of Biological Sciences

Adipokines and vascular health in treated HIV infection

(2013) Chris T. Longenecker et al.   AIDS

A role for spermine oxidase as a mediator of reactive oxygen species production in HIV-Tat-induced neuronal toxicity

(2013) Caterina Capone et al.   FREE RADICAL BIOLOGY AND MEDICINE

HIV Tat Induces Expression of ICAM-1 in HUVECs: Implications for miR-221/-222 in HIV-Associated Cardiomyopathy

(2013) Ming Duan et al.   PLoS One

HIV-1 Tat Promotes Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) vIL-6-Induced Angiogenesis and Tumorigenesis by Regulating PI3K/PTEN/AKT/GSK-3β Signaling Pathway

(2013) Feng Zhou et al.   PLoS One

HIV-1 Vpr Induces Adipose Dysfunction in Vivo Through Reciprocal Effects on PPAR/GR Co-Regulation

(2013) N. Agarwal et al.   Science Translational Medicine

Increased coronary atherosclerosis and immune activation in HIV-1 elite controllers

(2012) Florencia Pereyra et al.   AIDS

Endothelial Dysfunction, Arterial Stiffening, and Intima-Media Thickening in Large Arteries from HIV-1 Transgenic Mice

(2012) Laura Hansen et al.   ANNALS OF BIOMEDICAL ENGINEERING

Body Fat Distribution and Risk of Cardiovascular Disease

(2012) Jean-Pierre Després   CIRCULATION

High leptin and resistin expression in chronic heart failure: adverse outcome in patients with dilated and inflammatory cardiomyopathy

(2012) Peter Bobbert et al.   EUROPEAN JOURNAL OF HEART FAILURE

Relative risk of cardiovascular disease among people living with HIV: a systematic review and meta-analysis

(2012) FM Islam et al.   HIV MEDICINE

Adipogenic/Lipid, Inflammatory, and Mitochondrial Parameters in Subcutaneous Adipose Tissue of Untreated HIV-1–Infected Long-Term Nonprogressors

(2012) Francesc Vidal et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

HIV-1 Tat protein impairs adipogenesis and induces the expression and secretion of proinflammatory cytokines in human SGBS adipocytes

(2011) Julieta Díaz-Delfín et al.   ANTIVIRAL THERAPY

Oxidative stress and endothelial dysfunction in hypertension

(2011) Eberhard Schulz et al.   HYPERTENSION RESEARCH

Soluble CD163 Made by Monocyte/Macrophages Is a Novel Marker of HIV Activity in Early and Chronic Infection Prior to and After Anti-retroviral Therapy

(2011) Tricia H. Burdo et al.   JOURNAL OF INFECTIOUS DISEASES

Obesity and Risk of Incident Heart Failure in Older Men With and Without Pre-Existing Coronary Heart Disease

(2011) S. Goya Wannamethee et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Ins and Outs of HIV-1 Tat

(2011) Solène Debaisieux et al.   TRAFFIC

Akt/Nox2/NF-κB signaling pathway is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation

(2010) Hong-Sheng Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Approach to Dyslipidemia, Lipodystrophy, and Cardiovascular Risk in Patients with HIV Infection

(2010) J. Gregory Troll   Current Atherosclerosis Reports

Interleukin-6 and d-dimer levels are associated with vascular dysfunction in patients with untreated HIV infection

(2010) J Baker et al.   HIV MEDICINE

HIV-associated lipodystrophy: from fat injury to premature aging

(2010) Martine Caron-Debarle et al.   TRENDS IN MOLECULAR MEDICINE

Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis

(2009) Priscilla Y Hsue et al.   AIDS

Dilated Cardiomyopathy in Transgenic Mice Expressing HIV Tat

(2009) Qiujuan Fang et al.   Cardiovascular Toxicology

Human immunodeficiency virus per se exerts atherogenic effects

(2008) Ugo Oliviero et al.   ATHEROSCLEROSIS