N-Acetylcysteine and Aripiprazole Improve Social Behavior and Cognition and Modulate Brain BDNF Levels in a Rat Model of Schizophrenia
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Title
N-Acetylcysteine and Aripiprazole Improve Social Behavior and Cognition and Modulate Brain BDNF Levels in a Rat Model of Schizophrenia
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 23, Issue 4, Pages 2125
Publisher
MDPI AG
Online
2022-02-16
DOI
10.3390/ijms23042125
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Note: Only part of the references are listed.- N ‐acetylcysteine for depression and glutamate changes in the left prefrontal cortex in adolescents and young adults at risk for bipolar disorder: A pilot study
- (2021) Fabiano G. Nery et al. Early Intervention in Psychiatry
- Glutathione Deficiency during Early Postnatal Development Causes Schizophrenia-Like Symptoms and a Reduction in BDNF Levels in the Cortex and Hippocampus of Adult Sprague–Dawley Rats
- (2021) Marta Anna Lech et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Impact of repeated co-treatment with escitalopram and aripiprazole on the schizophrenia-like behaviors and BDNF mRNA expression in the adult Sprague–Dawley rats exposed to glutathione deficit during early postnatal development of the brain
- (2021) Marta A. Lech et al. Pharmacological Reports
- Is There a Glutathione Centered Redox Dysregulation Subtype of Schizophrenia?
- (2021) Lena Palaniyappan et al. Antioxidants
- Dopamine and glutamate in schizophrenia: biology, symptoms and treatment
- (2020) Robert A. McCutcheon et al. World Psychiatry
- Effect of combined treatment with aripiprazole and antidepressants on the MK-801-induced deficits in recognition memory in novel recognition test and on the release of monoamines in the rat frontal cortex
- (2020) Marta Hereta et al. BEHAVIOURAL BRAIN RESEARCH
- Assessing Brain Metabolism With 7-T Proton Magnetic Resonance Spectroscopy in Patients With First-Episode Psychosis
- (2019) Anna M. Wang et al. JAMA Psychiatry
- The glutathione cycle shapes synaptic glutamate activity
- (2019) Thomas W. Sedlak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Co-treatment with antidepressants and aripiprazole reversed the MK-801-induced some negative symptoms of schizophrenia in rats
- (2019) Marta Hereta et al. Pharmacological Reports
- NMDAR Hypofunction Animal Models of Schizophrenia
- (2019) Gloria Lee et al. Frontiers in Molecular Neuroscience
- Glutathione Deficiency and Alterations in the Sulfur Amino Acid Homeostasis during Early Postnatal Development as Potential Triggering Factors for Schizophrenia-Like Behavior in Adult Rats
- (2019) Magdalena Górny et al. MOLECULES
- Improvement of cognitive function in schizophrenia with N-acetylcysteine: A theoretical review
- (2018) Caitlin O. B. Yolland et al. NUTRITIONAL NEUROSCIENCE
- Antioxidant defense in schizophrenia and bipolar disorder: A meta-analysis of MRS studies of anterior cingulate glutathione
- (2018) Tushar Kanti Das et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Effects of 12-month, double-blind N-acetyl cysteine on symptoms, cognition and brain morphology in early phase schizophrenia spectrum disorders
- (2018) Alan Breier et al. SCHIZOPHRENIA RESEARCH
- Cystine/Glutamate Antiporter and Aripiprazole Compensate NMDA Antagonist-Induced Dysfunction of Thalamocortical L-Glutamatergic Transmission
- (2018) Kouji Fukuyama et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The effect of N-acetylcysteine (NAC) on human cognition – A systematic review
- (2017) David R. Skvarc et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- N-acetylcysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis
- (2017) Philippe Conus et al. SCHIZOPHRENIA BULLETIN
- N-acetylcysteine in the treatment of psychiatric disorders: current status and future prospects
- (2016) Alessandro Minarini et al. Expert Opinion on Drug Metabolism & Toxicology
- Cognitive effects of adjunctive N-acetyl cysteine in psychosis
- (2016) M. Rapado-Castro et al. PSYCHOLOGICAL MEDICINE
- Gene × Environment Interactions in Schizophrenia: Evidence from Genetic Mouse Models
- (2016) Paula Moran et al. NEURAL PLASTICITY
- Main path and byways: non-vesicular glutamate release by system xc−as an important modifier of glutamatergic neurotransmission
- (2015) Ann Massie et al. JOURNAL OF NEUROCHEMISTRY
- DNA Methylation in Memory Formation
- (2015) Frankie D. Heyward et al. NEUROSCIENTIST
- The effect of combined treatment with risperidone and antidepressants on the MK-801-induced deficits in the social interaction test in rats
- (2015) Katarzyna Kamińska et al. Pharmacological Reports
- Prenatal LPS-exposure – a neurodevelopmental rat model of schizophrenia – differentially affects cognitive functions, myelination and parvalbumin expression in male and female offspring
- (2015) Lena Wischhof et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Targeting Oxidative Stress and Aberrant Critical Period Plasticity in the Developmental Trajectory to Schizophrenia
- (2015) Kim Q. Do et al. SCHIZOPHRENIA BULLETIN
- The Longitudinal Course of Cognitive Impairment in Schizophrenia
- (2014) Richard S. E. Keefe JOURNAL OF CLINICAL PSYCHIATRY
- The Early Longitudinal Course of Cognitive Deficits in Schizophrenia
- (2014) Keith H. Nuechterlein et al. JOURNAL OF CLINICAL PSYCHIATRY
- N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action
- (2014) Olivia Dean et al. JOURNAL OF PSYCHIATRY & NEUROSCIENCE
- N-Acetylcysteine as an Adjunct to Risperidone for Treatment of Negative Symptoms in Patients With Chronic Schizophrenia
- (2013) Mehdi Farokhnia et al. CLINICAL NEUROPHARMACOLOGY
- Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents
- (2012) S Miyamoto et al. MOLECULAR PSYCHIATRY
- Neurodevelopmental model of schizophrenia: update 2012
- (2012) J L Rapoport et al. MOLECULAR PSYCHIATRY
- Glutathione is a physiologic reservoir of neuronal glutamate
- (2011) Minori Koga et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Dopamine D2 and serotonin 5-HT1A receptors mediate the actions of aripiprazole in mesocortical and mesoaccumbens transmission
- (2011) Shunsuke Tanahashi et al. NEUROPHARMACOLOGY
- Postnatal Developmental Trajectories of Neural Circuits in the Primate Prefrontal Cortex: Identifying Sensitive Periods for Vulnerability to Schizophrenia
- (2011) G. D. Hoftman et al. SCHIZOPHRENIA BULLETIN
- Magnetic Resonance Spectroscopy Study of the Antioxidant Defense System in Schizophrenia
- (2010) Daisuke Matsuzawa et al. ANTIOXIDANTS & REDOX SIGNALING
- Childhood onset schizophrenia: support for a progressive neurodevelopmental disorder
- (2010) Judith L. Rapoport et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders
- (2010) Jeremy W. Gawryluk et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- The environment and schizophrenia
- (2010) Jim van Os et al. NATURE
- DNA methylation and memory formation
- (2010) Jeremy J Day et al. NATURE NEUROSCIENCE
- Animal models of neuropsychiatric disorders
- (2010) Eric J Nestler et al. NATURE NEUROSCIENCE
- Effects of aripiprazole on MK-801-induced prepulse inhibition deficits and mitogen-activated protein kinase signal transduction pathway
- (2010) Daisuke Ishii et al. NEUROSCIENCE LETTERS
- Buthionine Sulfoximine, an Experimental Tool to Induce Glutathione Deficiency: Elucidation of Glutathione and Ascorbate in Their Role as Antioxidants
- (2010) Harry P. Broquist NUTRITION REVIEWS
- Effects of aripiprazole, olanzapine, and haloperidol in a model of cognitive deficit of schizophrenia in rats: relationship with glutamate release in the medial prefrontal cortex
- (2010) Mirjana Carli et al. PSYCHOPHARMACOLOGY
- Gestational methylazoxymethanol acetate administration: A developmental disruption model of schizophrenia
- (2009) Daniel J. Lodge et al. BEHAVIOURAL BRAIN RESEARCH
- Brain weight in males is correlated with DNA methylation at IGF2
- (2009) R Pidsley et al. MOLECULAR PSYCHIATRY
- The neonatal ventral hippocampal lesion as a heuristic neurodevelopmental model of schizophrenia
- (2008) Kuei Y. Tseng et al. BEHAVIOURAL BRAIN RESEARCH
- N-Acetyl Cysteine as a Glutathione Precursor for Schizophrenia—A Double-Blind, Randomized, Placebo-Controlled Trial
- (2008) Michael Berk et al. BIOLOGICAL PSYCHIATRY
- Differential effects of ziprasidone and haloperidol on immobilization stress-induced mRNA BDNF expression in the hippocampus and neocortex of rats
- (2008) Sung Woo Park et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders
- (2008) Gerard Sanacora et al. NATURE REVIEWS DRUG DISCOVERY
- Why do many psychiatric disorders emerge during adolescence?
- (2008) Tomáš Paus et al. NATURE REVIEWS NEUROSCIENCE
- Brain-Derived Neurotropic Factor/TrkB Signaling in the Pathogenesis and Novel Pharmacotherapy of Schizophrenia
- (2008) Anilkumar Pillai NEUROSIGNALS
- Antipsychotic Drugs: Comparison in Animal Models of Efficacy, Neurotransmitter Regulation, and Neuroprotection
- (2008) J. A. Lieberman et al. PHARMACOLOGICAL REVIEWS
- Gene-Environment Interactions in Schizophrenia: Review of Epidemiological Findings and Future Directions
- (2008) J. van Os et al. SCHIZOPHRENIA BULLETIN
- BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory?
- (2007) Yuan Lu et al. NEUROBIOLOGY OF LEARNING AND MEMORY
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