Methods of Measuring Mitochondrial Potassium Channels: A Critical Assessment

Dual-process brain mitochondria isolation preserves function and clarifies protein composition

(2021) Maria F. Noterman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solubilization, purification, and functional reconstitution of human ROMK potassium channel in copolymer styrene-maleic acid (SMA) nanodiscs

(2021) Milena Krajewska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Ion transport mechanism in gramicidin A channels formed in floating bilayer lipid membranes supported on gold electrodes

(2021) ZhangFei Su et al.   ELECTROCHIMICA ACTA

Lipid Nanoparticles—From Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement

(2021) Rumiana Tenchov et al.   ACS Nano

TASK-1 regulates mitochondrial function under hypoxia

(2021) Yang Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of the Large-Conductance Ca2+-Regulated Potassium Channel in Mitochondria of Human Bronchial Epithelial Cells

(2021) Aleksandra Sek et al.   MOLECULES

The mechanism of MICU-dependent gating of the mitochondrial Ca2+uniporter

(2021) Vivek Garg et al.   eLife

Solubilization of artificial mitochondrial membranes by amphiphilic copolymers of different charge

(2021) Kevin Janson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cytoprotective effects of the flavonoid quercetin by activating mitochondrial BKCa channels in endothelial cells.

(2021) Rafał Paweł Kampa et al.   BIOMEDICINE & PHARMACOTHERAPY

Mitochondrial K+ channels and their implications for disease mechanisms

(2021) Vanessa Checchetto et al.   PHARMACOLOGY & THERAPEUTICS

Properties of electrode-supported lipid cubic mesophase films with embedded gramicidin A: structure and ion-transport studies

(2021) Aleksandra Buta et al.   BIOELECTROCHEMISTRY

Structure and Functional Characterization of Membrane Integral Proteins in the Lipid Cubic Phase

(2020) Dianfan Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Development of a new simple mitochondria-targeted fluorescent K+ sensor and the application in high-throughput monitoring K+ fluxes

(2020) Juewei Ning et al.   SENSORS AND ACTUATORS B-CHEMICAL

New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins

(2020) Gabriella Angiulli et al.   eLife

ER membranes exhibit phase behavior at sites of organelle contact

(2020) Christopher King et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent advances of non-lamellar lyotropic liquid crystalline nanoparticles in nanomedicine

(2020) Sergio Murgia et al.   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

Heme is required for carbon monoxide activation of mitochondrial BKCa channel

(2020) Daria Rotko et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mitochondrial ion channels as targets for cardioprotection

(2020) Derek J. Hausenloy et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Molecular nature and regulation of the mitochondrial permeability transition pore(s), drug target(s) in cardioprotection

(2020) Michela Carraro et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Channels and transporters for inorganic ions in plant mitochondria: Prediction and facts

(2020) Ute C. Vothknecht et al.   MITOCHONDRION

Mitochondrial Potassium Channels as Druggable Targets

(2020) Antoni Wrzosek et al.   Biomolecules

Potassium Ion Fluorescence Probes: Structures, Properties and Bioimaging

(2020) Karthik Sambath et al.   ChemPhotoChem

Naringenin as an opener of mitochondrial potassium channels in dermal fibroblasts

(2019) Rafal Pawel Kampa et al.   EXPERIMENTAL DERMATOLOGY

Native Nanodiscs and the Convergence of Lipidomics, Metabolomics, Interactomics and Proteomics

(2019) Michael Overduin et al.   Applied Sciences-Basel

Identification of an ATP-sensitive potassium channel in mitochondria

(2019) Angela Paggio et al.   NATURE

Single-Channel Properties of the ROMK-Pore-Forming Subunit of the Mitochondrial ATP-Sensitive Potassium Channel

(2019) Michał Laskowski et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Purified F-ATP synthase forms a Ca2+-dependent high-conductance channel matching the mitochondrial permeability transition pore

(2019) Andrea Urbani et al.   Nature Communications

A mitochondrial megachannel resides in monomeric F1FO ATP synthase

(2019) Nelli Mnatsakanyan et al.   Nature Communications

Mechanosensitivity of mitochondrial large-conductance calcium-activated potassium channels

(2018) Agnieszka Walewska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Evidence for a mitochondrial ATP-regulated potassium channel in human dermal fibroblasts

(2018) Piotr Bednarczyk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Novel Channels of the Outer Membrane of Mitochondria: Recent Discoveries Change Our View

(2018) Vanessa Checchetto et al.   BIOESSAYS

Lipidic liquid crystalline cubic phases for preparation of ATP-hydrolysing enzyme electrodes

(2018) Martina Zatloukalová et al.   BIOSENSORS & BIOELECTRONICS

Lysosomal Potassium Channels: Potential Roles in Lysosomal Function and Neurodegenerative Diseases

(2018) Xinghua Feng et al.   CNS & Neurological Disorders-Drug Targets

Interacting organelles

(2018) Sarah Cohen et al.   CURRENT OPINION IN CELL BIOLOGY

Cardiac metabolic effects of KNa1.2 channel deletion and evidence for its mitochondrial localization

(2018) Charles O. Smith et al.   FASEB JOURNAL

Reconstitution and functional characterization of ion channels from nanodiscs in lipid bilayers

(2018) Laura-Marie Winterstein et al.   JOURNAL OF GENERAL PHYSIOLOGY

Different approaches to modeling analysis of mitochondrial swelling

(2018) Sabzali Javadov et al.   MITOCHONDRION

Design of ultra-swollen lipidic mesophases for the crystallization of membrane proteins with large extracellular domains

(2018) Alexandru Zabara et al.   Nature Communications

The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution

(2018) Michael Luke Carlson et al.   eLife

Pharmacological modulation of mitochondrial ion channels

(2018) Luigi Leanza et al.   BRITISH JOURNAL OF PHARMACOLOGY

Memtein: The fundamental unit of membrane-protein structure and function

(2018) Michael Overduin et al.   CHEMISTRY AND PHYSICS OF LIPIDS

The cubicon method for concentrating membrane proteins in the cubic mesophase

(2017) Pikyee Ma et al.   Nature Protocols

Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo

(2017) Helmut Bischof et al.   Nature Communications

A large-conductance calcium-regulated K+ channel in human dermal fibroblast mitochondria

(2016) A. Kicinska et al.   BIOCHEMICAL JOURNAL

What do we not know about mitochondrial potassium channels?

(2016) Michał Laskowski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Isolation of yeast complex IV in native lipid nanodiscs

(2016) Irina A. Smirnova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Impact of intracellular ion channels on cancer development and progression

(2016) Roberta Peruzzo et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Lyotropic Liquid Crystalline Cubic Phases as Versatile Host Matrices for Membrane-Bound Enzymes

(2016) Wenjie Sun et al.   Journal of Physical Chemistry Letters

A macroscopic H+and Cl−ions pump via reconstitution of EcClC membrane proteins in lipidic cubic mesophases

(2016) Chiara Speziale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring the structural relationship between encapsulated antimicrobial peptides and the bilayer membrane mimetic lipidic cubic phase: studies with gramicidin A′

(2016) Thomas G. Meikle et al.   RSC Advances

Whole-cell Patch-clamp Recordings in Brain Slices

(2016) Amir Segev et al.   Jove-Journal of Visualized Experiments

A Highly Selective Mitochondria-Targeting Fluorescent K+Sensor

(2015) Xiangxing Kong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Expression and function of Kv7.4 channels in rat cardiac mitochondria: possible targets for cardioprotection

(2015) Lara Testai et al.   CARDIOVASCULAR RESEARCH

Organellar channels and transporters

(2015) Haoxing Xu et al.   CELL CALCIUM

Fluorescent probes and bioimaging: alkali metals, alkaline earth metals and pH

(2015) Jun Yin et al.   CHEMICAL SOCIETY REVIEWS

BK Channels Alleviate Lysosomal Storage Diseases by Providing Positive Feedback Regulation of Lysosomal Ca2+ Release

(2015) Qi Cao et al.   DEVELOPMENTAL CELL

The styrene–maleic acid copolymer: a versatile tool in membrane research

(2015) Jonas M. Dörr et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Mitochondrial large-conductance potassium channel from Dictyostelium discoideum

(2015) Michal Laskowski et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A comprehensive review of the lipid cubic phase orin mesomethod for crystallizing membrane and soluble proteins and complexes

(2015) Martin Caffrey   Acta Crystallographica Section F-Structural Biology Communications

Design and Assembly of pH-Sensitive Lipidic Cubic Phase Matrices for Drug Release

(2014) Ewa Nazaruk et al.   LANGMUIR

Molecular and functional identification of a mitochondrial ryanodine receptor in neurons

(2014) Regina Jakob et al.   NEUROSCIENCE LETTERS

Mitochondrial Channels: Ion Fluxes and More

(2014) Ildiko Szabo et al.   PHYSIOLOGICAL REVIEWS

A Novel Optical Intracellular Imaging Approach for Potassium Dynamics in Astrocytes

(2014) Theresa S. Rimmele et al.   PLoS One

Large-conductance Ca2+-activated potassium channel in mitochondria of endothelial EA.hy926 cells

(2013) Piotr Bednarczyk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Suspended Lipid Bilayer for Optical and Electrical Measurements of Single Ion Channel Proteins

(2013) Suneth P. Rajapaksha et al.   ANALYTICAL CHEMISTRY

Mitochondria as a pharmacological target: Magnum overview

(2013) Anna Olszewska et al.   IUBMB LIFE

Mitochondrial Small Conductance SK2 Channels Prevent Glutamate-induced Oxytosis and Mitochondrial Dysfunction

(2013) Amalia M. Dolga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Potassium Channel in the Mitochondria of Human Keratinocytes

(2013) Renata Toczyłowska-Mamińska et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain

(2013) Piotr Bednarczyk et al.   PLoS One

mitoBKCa is encoded by the Kcnma1 gene, and a splicing sequence defines its mitochondrial location

(2013) H. Singh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dimers of mitochondrial ATP synthase form the permeability transition pore

(2013) V. Giorgio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanostructured bicontinuous cubic lipid self-assembly materials as matrices for protein encapsulation

(2013) Charlotte E. Conn et al.   Soft Matter

Protection against cardiac injury by small Ca2+-sensitive K+ channels identified in guinea pig cardiac inner mitochondrial membrane

(2012) David F. Stowe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mitochondrial ROMK Channel Is a Molecular Component of MitoK ATP

(2012) D. Brian Foster et al.   CIRCULATION RESEARCH

Crystal Structure of a Voltage-gated K+Channel Pore Module in a Closed State in Lipid Membranes

(2012) Jose S. Santos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular BKCa(iBKCa) channels

(2012) Harpreet Singh et al.   JOURNAL OF PHYSIOLOGY-LONDON

Horizontal Bilayer for Electrical and Optical Recordings

(2012) Philipp Bartsch et al.   Materials

A Step-by-step Method for the Reconstitution of an ABC Transporter into Nanodisc Lipid Particles

(2012) Huan Bao et al.   Jove-Journal of Visualized Experiments

ATP-Sensitive Cation-channel in Wheat (Triticum durum Desf.): Identification and Characterization of a Plant Mitochondrial Channel by Patch-clamp

(2011) Umberto De Marchi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Lipidic cubic phase technologies for membrane protein structural studies

(2011) Vadim Cherezov   CURRENT OPINION IN STRUCTURAL BIOLOGY

Single Channel Characterization of the Mitochondrial Ryanodine Receptor in Heart Mitoplasts

(2011) Shin-Young Ryu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physiology of potassium channels in the inner membrane of mitochondria

(2011) Ildikò Szabò et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment

(2011) Theresa Tiefenbrunn et al.   PLoS One

SLO-2 Is Cytoprotective and Contributes to Mitochondrial Potassium Transport

(2011) Andrew P. Wojtovich et al.   PLoS One

Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes

(2011) D. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystallizing Transmembrane Peptides in Lipidic Mesophases

(2010) Nicole Höfer et al.   BIOPHYSICAL JOURNAL

A Novel Mitochondrial K ATP Channel Assay

(2010) Andrew P. Wojtovich et al.   CIRCULATION RESEARCH

Pharmacology of mitochondrial potassium channels: dark side of the field

(2010) Adam Szewczyk et al.   FEBS LETTERS

Differential Increase of Mitochondrial Matrix Volume by Sevoflurane in Isolated Cardiac Mitochondria

(2009) Matthias L. Riess et al.   ANESTHESIA AND ANALGESIA

A large-conductance calcium-activated potassium channel in potato (Solanum tuberosum) tuber mitochondria

(2009) Izabela Koszela-Piotrowska et al.   BIOCHEMICAL JOURNAL

An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtKCa3.1

(2009) Nicola Sassi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Energetic performance is improved by specific activation of K+ fluxes through KCa channels in heart mitochondria

(2009) Miguel A. Aon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Solid supported lipid membranes: New concepts for the biomimetic functionalization of solid surfaces

(2009) W. Knoll et al.   Biointerphases

Intermediate conductance Ca2+-activated potassium channel (KCa3.1) in the inner mitochondrial membrane of human colon cancer cells

(2009) Umberto De Marchi et al.   CELL CALCIUM

Mitochondrial potassium channels

(2009) Adam Szewczyk et al.   IUBMB LIFE

Single channel studies of the ATP-regulated potassium channel in brain mitochondria

(2009) Katarzyna Choma et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Design and Characterization of Novel Tether Layer for Coupling of a Bilayer Lipid Membrane to the Surface of Gold

(2009) Magdalena Brzozowska et al.   LANGMUIR

High-Throughput Screening Reveals a Small-Molecule Inhibitor of the Renal Outer Medullary Potassium Channel and Kir7.1

(2009) L. M. Lewis et al.   MOLECULAR PHARMACOLOGY

Equilibrium distribution of K+ ions in the hydrophilic spacer of tethered bilayer lipid membranes

(2009) Lucia Becucci et al.   Soft Matter

Intramitochondrial signaling: interactions among mitoKATP, PKCε, ROS, and MPT

(2008) Alexandre D. T. Costa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

BK channel openers inhibit ROS production of isolated rat brain mitochondria

(2008) Bogusz Kulawiak et al.   EXPERIMENTAL NEUROLOGY

New properties of mitochondrial ATP-regulated potassium channels

(2008) Piotr Bednarczyk et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES