Autoantibodies Targeting AT1- and ETA-Receptors Link Endothelial Proliferation and Coagulation via Ets-1 Transcription Factor

Prediction and primary prevention of major vascular complications in systemic sclerosis

(2021) Cosimo Bruni et al.   European Journal of Internal Medicine

Single-cell transcriptome analysis identifies skin-specific T-cell responses in systemic sclerosis

(2021) Alyxzandria M Gaydosik et al.   ANNALS OF THE RHEUMATIC DISEASES

Single-cell analysis of salt-induced hypertensive mouse aortae reveals cellular heterogeneity and state changes

(2021) Ka Zhang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Spatially Resolved Transcriptomic Analysis of Acute Kidney Injury in a Female Murine Model

(2021) Eryn E. Dixon et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Single-cell RNA sequencing reveals cell type- and artery-specific vascular remodeling in male spontaneously hypertensive rats

(2020) Jun Cheng et al.   CARDIOVASCULAR RESEARCH

Angiotensin II Stimulates the Proliferation and Migration of Lymphatic Endothelial Cells Through Angiotensin Type 1 Receptors

(2020) Qiu-Yue Lin et al.   Frontiers in Physiology

Scleroderma renal crisis (SRC): risk factors for an increasingly rare organ complication

(2019) Pia Moinzadeh et al.   JOURNAL OF RHEUMATOLOGY

Therapy of scleroderma renal crisis: State of the art

(2018) Elisabetta Zanatta et al.   AUTOIMMUNITY REVIEWS

Endothelin-1 triggers human peritoneal mesothelial cells’ proliferation via ERK1/2-Ets-1 signaling pathway and contributes to endothelial cell angiogenesis

(2018) Nan Zhu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis

(2018) Otavio Cabral-Marques et al.   Nature Communications

Single Cell RNA Sequencing Identifies HSPG2 and APLNR as Markers of Endothelial Cell Injury in Systemic Sclerosis Skin

(2018) Sokratis A. Apostolidis et al.   Frontiers in Immunology

Lipo-PGE1 suppresses collagen production in human dermal fibroblasts via the ERK/Ets-1 signaling pathway

(2017) Yoolhee Yang et al.   PLoS One

Non-HLA antibodies against endothelial targets bridging allo- and autoimmunity

(2016) Duska Dragun et al.   KIDNEY INTERNATIONAL

Scleroderma renal crisis and renal involvement in systemic sclerosis

(2016) Thasia G. Woodworth et al.   Nature Reviews Nephrology

Ets-1 Targeted by MicroRNA-221 Regulates Angiotensin II-Induced Renal Fibroblast Activation and Fibrosis

(2014) Jia Di et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Scleroderma Renal Crisis

(2014) L. Mouthon et al.   JOURNAL OF RHEUMATOLOGY

Autoantibodies to angiotensin and endothelin receptors in systemic sclerosis induce cellular and systemic events associated with disease pathogenesis

(2014) Angela Kill et al.   ARTHRITIS RESEARCH & THERAPY

Pretransplant Sensitization Against Angiotensin II Type 1 Receptor Is a Risk Factor for Acute Rejection and Graft Loss

(2013) M. Giral et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The Transcription Factor E26 Transformation-Specific Sequence-1 Mediates Neointima Formation in Arteriovenous Fistula

(2013) W. Feng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Exposure to ACE inhibitors prior to the onset of scleroderma renal crisis—Results from the International Scleroderma Renal Crisis Survey

(2013) Marie Hudson et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Ets-1 transcription is required in tissue factor driven microvessel formation and stabilization

(2012) Gemma Arderiu et al.   ANGIOGENESIS

Role of the Transcription Factor Erythroblastosis Virus E26 Oncogen Homolog-1 (ETS-1) as Mediator of the Renal Proinflammatory and Profibrotic Effects of Angiotensin II

(2012) Wenguang Feng et al.   HYPERTENSION

Tissue factor-Akt signaling triggers microvessel formation

(2012) G. ARDERIU et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Non-HLA Antibodies Targeting Vascular Receptors Enhance Alloimmune Response and Microvasculopathy After Heart Transplantation

(2012) Nicola E. Hiemann et al.   TRANSPLANTATION

The dual nature of Ets-1: Focus to the pathogenesis of systemic lupus erythematosus

(2011) Rui-Xue Leng et al.   AUTOIMMUNITY REVIEWS

Bivalirudin Inhibits Periprocedural Platelet Function and Tissue Factor Expression of Human Smooth Muscle Cells

(2011) Wojciech Pepke et al.   Cardiovascular Therapeutics

Endothelin-1 Signaling Promotes Fibrosis In Vitro in a Bronchopulmonary Dysplasia Model by Activating the Extrinsic Coagulation Cascade

(2011) K. Kambas et al.   JOURNAL OF IMMUNOLOGY

Involvement of functional autoantibodies against vascular receptors in systemic sclerosis

(2010) G. Riemekasten et al.   ANNALS OF THE RHEUMATIC DISEASES

Atherosclerotic-like process in aortic stenosis: Activation of the tissue factor–thrombin pathway and potential role through osteopontin alteration

(2010) Joke Breyne et al.   ATHEROSCLEROSIS

Angiotensin II–Mediated Microvascular Thrombosis

(2010) Elena Y. Senchenkova et al.   HYPERTENSION

Association of RNA Polymerase III Antibodies with Scleroderma Renal Crisis

(2010) B. NGUYEN et al.   JOURNAL OF RHEUMATOLOGY

Antiphospholipid syndrome treatment beyond anticoagulation: are we there yet?

(2010) SS Pierangeli et al.   LUPUS

Autoantibodies as predictive tools in systemic sclerosis

(2010) Svetlana I. Nihtyanova et al.   Nature Reviews Rheumatology

In Vitro Effects of Antiphospholipid Syndrome-IgG Fractions and Human Monoclonal Antiphospholipid IgG Antibody on Human Umbilical Vein Endothelial Cells and Monocytes

(2009) Natascha Clemens et al.   Annals of the New York Academy of Sciences

Dabigatran, a direct thrombin inhibitor, demonstrates antifibrotic effects on lung fibroblasts

(2009) Galina S. Bogatkevich et al.   ARTHRITIS AND RHEUMATISM

Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis

(2009) G. Wei et al.   BLOOD

The tight junction protein ZO-2 mediates proliferation of vascular smooth muscle cells via regulation of Stat1

(2009) Angelika Kusch et al.   CARDIOVASCULAR RESEARCH

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

Proliferative stimulation of the vascular endothelin-1 axis in vitro and ex vivo by infection with Chlamydia pneumoniae

(2009) Jan M. Kern et al.   THROMBOSIS AND HAEMOSTASIS

Regulation of endothelial proliferation by the renin–angiotensin system in human umbilical vein endothelial cells

(2008) D Herr et al.   REPRODUCTION