Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy

α-synuclein impairs autophagosome maturation through abnormal actin stabilization

(2021) Souvarish Sarkar et al.   PLoS Genetics

p62: Friend or Foe? Evidences for OncoJanus and NeuroJanus Roles

(2020) Sonia Emanuele et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinson’s disease

(2019) Takuya Uehara et al.   Scientific Reports

Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila

(2019) Ricardo Aparicio et al.   Cell Reports

Thymoquinone prevents neurodegeneration against MPTP in vivo and modulates α-synuclein aggregation in vitro

(2019) Mustafa T. Ardah et al.   NEUROCHEMISTRY INTERNATIONAL

Nitric Oxide-Dependent Protein Post-Translational Modifications Impair Mitochondrial Function and Metabolism to Contribute to Neurodegenerative Diseases

(2019) Tomohiro Nakamura et al.   ANTIOXIDANTS & REDOX SIGNALING

Neuroprotective Effects of Pomegranate Juice against Parkinson’s Disease and Presence of Ellagitannins-Derived Metabolite—Urolithin A—In the Brain

(2019) Małgorzata Kujawska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Upregulated Autophagy in Sertoli Cells of Ethanol-Treated Rats Is Associated with Induction of Inducible Nitric Oxide Synthase (iNOS), Androgen Receptor Suppression and Germ Cell Apoptosis

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroprotective effects of Kukoamine A on neurotoxin-induced Parkinson's model through apoptosis inhibition and autophagy enhancement

(2017) XiaoLong Hu et al.   NEUROPHARMACOLOGY

Autophagy and Alpha-Synuclein: Relevance to Parkinson's Disease and Related Synucleopathies

(2016) Maria Xilouri et al.   MOVEMENT DISORDERS

The Effects of Ellagic Acid upon Brain Cells: A Mechanistic View and Future Directions

(2016) Marcos Roberto de Oliveira   NEUROCHEMICAL RESEARCH

Ginsenoside Rb1 inhibits fibrillation and toxicity of alpha-synuclein and disaggregates preformed fibrils

(2015) Mustafa T. Ardah et al.   NEUROBIOLOGY OF DISEASE

Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection

(2015) Wylly Ramsés García-Niño et al.   PHARMACOLOGICAL RESEARCH

Ellagic Acid Mitigates SNO-PDI Induced Aggregation of Parkinsonian Biomarkers

(2014) Parijat Kabiraj et al.   ACS Chemical Neuroscience

Structure activity relationship of phenolic acid inhibitors of α-synuclein fibril formation and toxicity

(2014) Mustafa T. Ardah et al.   Frontiers in Aging Neuroscience

TFEB

(2013) Mickael Decressac et al.   Autophagy

Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy

(2013) Selcuk A. Tanik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TFEB-mediated autophagy rescues midbrain dopamine neurons from  -synuclein toxicity

(2013) M. Decressac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of the Autophagic Bcl-2/Beclin 1 Interaction

(2012) Jean-Paul Decuypere et al.   Cells

Direct Interaction of α-Synuclein and AKT Regulates IGF-1 Signaling: Implication of Parkinson Disease

(2011) Ji-Yun Chung et al.   NEUROSIGNALS

In vivo demonstration that  -synuclein oligomers are toxic

(2011) B. Winner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

S-Nitrosylation of Critical Protein Thiols Mediates Protein Misfolding and Mitochondrial Dysfunction in Neurodegenerative Diseases

(2010) Tomohiro Nakamura et al.   ANTIOXIDANTS & REDOX SIGNALING

Phosphorylation at Ser-129 but Not the Phosphomimics S129E/D Inhibits the Fibrillation of α-Synuclein

(2008) Katerina E. Paleologou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY