Irradiation Activates MZF1 to Inhibit miR-541-5p Expression and Promote Epithelial-Mesenchymal Transition (EMT) in Radiation-Induced Pulmonary Fibrosis (RIPF) by Upregulating Slug

Circular RNA FLNA acts as a sponge of miR-486-3p in promoting lung cancer progression via regulating XRCC1 and CYP1A1

(2021) Jiongwei Pan et al.   CANCER GENE THERAPY

miR-541-3p enhances the radiosensitivity of prostate cancer cells by inhibiting HSP27 expression and downregulating β-catenin

(2021) Zhenhua He et al.   Cell Death Discovery

Circulating MicroRNA-486 and MicroRNA-146a serve as potential biomarkers of sarcopenia in the older adults

(2021) Huang-Chun Liu et al.   BMC Geriatrics

Interplay between Metabolism Reprogramming and Epithelial-to-Mesenchymal Transition in Cancer Stem Cells

(2021) Yoann Daniel et al.   Cancers

Zinc Finger Transcription Factor MZF1—A Specific Regulator of Cancer Invasion

(2020) Ditte Marie Brix et al.   Cells

Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Radiation-Induced Lung Injury via miRNA-214-3p

(2020) Xudan Lei et al.   ANTIOXIDANTS & REDOX SIGNALING

miR-541 serves as a prognostic biomarker of osteosarcoma and its regulatory effect on tumor cell proliferation, migration and invasion by targeting TGIF2

(2020) Chunlei Liu et al.   Diagnostic Pathology

Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer

(2020) Maria Victoria Recouvreux et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CBP-mediated Slug acetylation stabilizes Slug and promotes EMT and migration of breast cancer cells

(2020) Xiaoyan Dai et al.   Science China-Life Sciences

HOXC10 promotes tumour metastasis by regulating the EMT-related gene Slug in ovarian cancer

(2020) Yulong Peng et al.   Aging-US

MiRNA-155–5p inhibits epithelium-to-mesenchymal transition (EMT) by targeting GSK-3β during radiation-induced pulmonary fibrosis

(2020) Duo Wang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

TBX3 promotes progression of pre‐invasive breast cancer cells by inducing EMT and directly up‐regulating SLUG

(2019) Milica Krstic et al.   JOURNAL OF PATHOLOGY

Radiation-Induced Lung Injury

(2019) Alexander N. Hanania et al.   CHEST

Myeloid Zinc Finger 1 (MZF1) Maintains the Mesenchymal Phenotype by Down-regulating IGF1R/p38 MAPK/ERα Signaling Pathway in High-level MZF1-expressing TNBC cells

(2019) CHIA-HERNG YUE et al.   ANTICANCER RESEARCH

Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease

(2019) Marcelo A. Mori et al.   Cell Metabolism

miR-541 potentiates the response of human hepatocellular carcinoma to sorafenib treatment by inhibiting autophagy

(2019) Wen-Ping Xu et al.   GUT

The transcription factor MZF1 differentially regulates murine Mtor promoter variants linked to tumor susceptibility

(2019) Shuling Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation-dependent stabilization of MZF1 upregulates N-cadherin expression during protein kinase CK2-mediated epithelial-mesenchymal transition

(2018) Hyeonseok Ko et al.   Oncogenesis

Transcriptional activation of miR-320a by ATF2, ELK1 and YY1 induces cancer cell apoptosis under ionizing radiation conditions

(2018) Zheng Hu et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Transcription Factor Myeloid Zinc-Finger 1 Suppresses Human Gastric Carcinogenesis by Interacting with Metallothionein 2A

(2018) Shuye Lin et al.   CLINICAL CANCER RESEARCH

MiR-541-5p regulates lung fibrosis by targeting cyclic nucleotide phosphodiesterase 1A

(2017) Liqin Ren et al.   EXPERIMENTAL LUNG RESEARCH

Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches

(2016) Julia Beermann et al.   PHYSIOLOGICAL REVIEWS

miRNA Deregulation in Cancer Cells and the Tumor Microenvironment

(2016) R. Rupaimoole et al.   Cancer Discovery

Role and Regulation of Myeloid Zinc Finger Protein 1 in Cancer

(2015) Taka Eguchi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK+ T-cell lymphoma

(2015) Deeksha Vishwamitra et al.   Molecular Cancer

Therapeutic targeting of microRNAs: current status and future challenges

(2014) Zhonghan Li et al.   NATURE REVIEWS DRUG DISCOVERY

Identification and consequences of miRNA–target interactions — beyond repression of gene expression

(2014) Jean Hausser et al.   NATURE REVIEWS GENETICS

Integrating microRNA and mRNA expression profiles in response to radiation-induced injury in rat lung

(2014) Ling Xie et al.   Radiation Oncology

SLUG: Critical regulator of epithelial cell identity in breast development and cancer

(2014) Sarah Phillips et al.   Cell Adhesion & Migration

IGF2BP1 promotes mesenchymal cell properties and migration of tumor-derived cells by enhancing the expression of LEF1 and SNAI2 (SLUG)

(2013) Anne Zirkel et al.   NUCLEIC ACIDS RESEARCH

The EMT regulator slug and lung carcinogenesis

(2011) J.-Y. Shih et al.   CARCINOGENESIS

The skinny on slug

(2010) Stephanie H. Shirley et al.   MOLECULAR CARCINOGENESIS

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

(2009) Jose Miguel López-Novoa et al.   EMBO Molecular Medicine

Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers

(2009) Catarina Castro Alves   Frontiers in Bioscience-Landmark