miR-29a-3p/THBS2 Axis Regulates PAH-Induced Cardiac Fibrosis

Plasma exosomal miR-596: a novel biomarker predicts survival in patients with idiopathic pulmonary artery hypertension

(2021) Yang Huang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Novel Pharmaceutical Strategy for Selective Abrogation of TSP1-Induced Vascular Dysfunction by Decoy Recombinant CD47 Soluble Receptor in Prophylaxis and Treatment Models

(2021) Molly Yao et al.   Biomedicines

Extracellular Vesicles of Mesenchymal Stem Cells: Therapeutic Properties Discovered with Extraordinary Success

(2021) Gabriella Racchetti et al.   Biomedicines

Role of thrombospondin‑1 and thrombospondin‑2 in cardiovascular diseases (Review)

(2020) Kaijie Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Micro RNA ‐483 amelioration of experimental pulmonary hypertension

(2020) Jin Zhang et al.   EMBO Molecular Medicine

Expression of serum miR‑27b and miR‑451 in patients with congenital heart disease associated pulmonary artery hypertension and risk factor analysis

(2020) Leiwang Long et al.   Experimental and Therapeutic Medicine

Emerging therapies for right ventricular dysfunction and failure

(2020) Anna Klinke et al.   Cardiovascular Diagnosis and Therapy

A strategic expression method of miR-29b and its anti-fibrotic effect based on RNA-sequencing analysis

(2020) Xiaoming Fan et al.   PLoS One

Exosomal miR-211 contributes to pulmonary hypertension via attenuating CaMK1/PPAR-γaxis

(2020) Shuhao Zhang et al.   VASCULAR PHARMACOLOGY

Thrombospondin-2 regulates extracellular matrix production, LOX levels, and cross-linking via downregulation of miR-29

(2019) N.E. Calabro et al.   MATRIX BIOLOGY

MiR-9 promotes tumorigenesis and angiogenesis and is activated by MYC and OCT4 in human glioma

(2019) Xu Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Thrombospondin-2

(2019) Tomoko Nakao et al.   International Heart Journal

Cancer-derived exosomal miR-221-3p promotes angiogenesis by targeting THBS2 in cervical squamous cell carcinoma

(2019) Xiang-Guang Wu et al.   ANGIOGENESIS

MicroRNA-21 and microRNA-29a modulate the expression of collagen in dermal fibroblasts of patients with systemic sclerosis

(2019) Saeideh Jafarinejad-Farsangi et al.   AUTOIMMUNITY

Mitochondrial protection by simvastatin against Angiotensin II‐mediated heart failure

(2019) Chong‐Chao Hsieh et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Extracellular Matrix in Ischemic and Nonischemic Heart Failure

(2019) Nikolaos G. Frangogiannis   CIRCULATION RESEARCH

Simvastatin Attenuates Cardiac Fibrosis via Regulation of Cardiomyocyte-Derived Exosome Secretion

(2019) Hsuan-Fu Kuo et al.   Journal of Clinical Medicine

Cardiomyocyte-Derived Exosomes: Biological Functions and Potential Therapeutic Implications

(2019) Hui Yu et al.   Frontiers in Physiology

Trans-Right–Ventricle and Transpulmonary MicroRNA Gradients in Human Pulmonary Arterial Hypertension

(2019) Philippe Chouvarine et al.   Pediatric Critical Care Medicine

Profiling of the plasma proteome across different stages of human heart failure

(2019) Anna Egerstedt et al.   Nature Communications

Clinical diagnostic value of circulating serum miR-509-3p in pulmonary arterial hypertension with congenital heart disease

(2018) Peizhe Tang   Hellenic Journal of Cardiology

MicroRNAs and diabetic kidney disease: Systematic review and bioinformatic analysis

(2018) Taís S. Assmann et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The harsh microenvironment in infarcted heart accelerates transplanted bone marrow mesenchymal stem cells injury: the role of injured cardiomyocytes-derived exosomes

(2018) Ming Hu et al.   Cell Death & Disease

Role of Extracellular Matrix in the Pathogenesis of Pulmonary Arterial Hypertension

(2018) Thenappan Thenappan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Thrombospondins: A Role in Cardiovascular Disease

(2017) Dimitry Chistiakov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling

(2017) Yassine Sassi et al.   Nature Communications

Integration of miRNA and mRNA expression profiles reveals microRNA-regulated networks during muscle wasting in cardiac cachexia

(2017) Leonardo N. Moraes et al.   Scientific Reports

Extracellular Vesicles in Cardiovascular Theranostics

(2017) Yihua Bei et al.   Theranostics

Modulators of right ventricular apoptosis and contractility in a rat model of pulmonary hypertension

(2016) Makhosazane Zungu-Edmondson et al.   CARDIOVASCULAR RESEARCH

Exosomal transfer of miR-30a between cardiomyocytes regulates autophagy after hypoxia

(2016) Yan Yang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Serum Endostatin Is a Genetically Determined Predictor of Survival in Pulmonary Arterial Hypertension

(2015) Rachel Damico et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

MicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial HypertensionNovelty and Significance

(2015) Lin Deng et al.   CIRCULATION RESEARCH

Key endothelial cell angiogenic mechanisms are stimulated by the circulating milieu in sickle cell disease and attenuated by hydroxyurea

(2015) F. C. M. Lopes et al.   HAEMATOLOGICA

Key endothelial cell angiogenic mechanisms are stimulated by the circulating milieu in sickle cell disease and attenuated by hydroxyurea

(2015) F. C. M. Lopes et al.   HAEMATOLOGICA

Distinct Differences in Gene Expression Patterns in Pulmonary Arteries of Patients with Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis with Pulmonary Hypertension

(2014) Julia Hoffmann et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cross Talk of Combined Gene and Cell Therapy in Ischemic Heart Disease: Role of Exosomal MicroRNA Transfer

(2014) S.-G. Ong et al.   CIRCULATION

Circulating Thrombospondin-2 Reflects Disease Severity and Predicts Outcome of Heart Failure With Reduced Ejection Fraction

(2014) Shinsuke Hanatani et al.   CIRCULATION JOURNAL

MicroRNA mimicry blocks pulmonary fibrosis

(2014) R. L. Montgomery et al.   EMBO Molecular Medicine

High serum levels of thrombospondin-2 correlate with poor prognosis of patients with heart failure with preserved ejection fraction

(2014) Yuichi Kimura et al.   HEART AND VESSELS

Reduced MicroRNA-150 Is Associated with Poor Survival in Pulmonary Arterial Hypertension

(2012) Christopher J. Rhodes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Lack of thrombospondin-2 reduces fibrosis and increases vascularity around cardiac cell grafts

(2012) Hans Reinecke et al.   CARDIOVASCULAR PATHOLOGY

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Matricellular Proteins in Cardiac Adaptation and Disease

(2012) Nikolaos G. Frangogiannis   PHYSIOLOGICAL REVIEWS

Cardiomyocyte Microvesicles Contain DNA/RNA and Convey Biological Messages to Target Cells

(2012) Anders Waldenström et al.   PLoS One

Retrograde Perfusion and Filling of Mouse Coronary Vasculature as Preparation for Micro Computed Tomography Imaging

(2012) Jill J. Weyers et al.   Jove-Journal of Visualized Experiments

Increased thrombospondin-2 in human fibrosclerotic and stenotic aortic valves

(2011) Virva Pohjolainen et al.   ATHEROSCLEROSIS

VennDiagram: a package for the generation of highly-customizable Venn and Euler diagrams in R

(2011) Hanbo Chen et al.   BMC BIOINFORMATICS

Non-cardiomyocyte microRNAs in heart failure

(2011) A. J. Tijsen et al.   CARDIOVASCULAR RESEARCH

Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy

(2011) Geert C. van Almen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Current and Evolving Echocardiographic Techniques for the Quantitative Evaluation of Cardiac Mechanics: ASE/EAE Consensus Statement on Methodology and Indications

(2011) Victor Mor-Avi et al.   JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY

miR-29 Is a Major Regulator of Genes Associated with Pulmonary Fibrosis

(2010) Leah Cushing et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis

(2010) Christoph Roderburg et al.   HEPATOLOGY

Absence of Thrombospondin-2 Causes Age-Related Dilated Cardiomyopathy

(2009) Melissa Swinnen et al.   CIRCULATION