It takes two to tango: The essential role of ER-mitochondrial contact sites in mitochondrial dynamics

Fission and fusion machineries converge at ER contact sites to regulate mitochondrial morphology

(2020) Robert G. Abrisch et al.   JOURNAL OF CELL BIOLOGY

Altered interplay between endoplasmic reticulum and mitochondria in Charcot–Marie–Tooth type 2A neuropathy

(2019) Nathalie Bernard-Marissal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrastructure and dynamics of the actin−myosin II cytoskeleton during mitochondrial fission

(2019) Changsong Yang et al.   NATURE CELL BIOLOGY

DJ-1 regulates the integrity and function of ER-mitochondria association through interaction with IP3R3-Grp75-VDAC1

(2019) Yi Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

(2018) Gian-Luca McLelland et al.   eLife

Dynamin-related protein 1 has membrane constricting and severing abilities sufficient for mitochondrial and peroxisomal fission

(2018) Sukrut C. Kamerkar et al.   Nature Communications

INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division

(2017) Rajarshi Chakrabarti et al.   JOURNAL OF CELL BIOLOGY

Receptor-mediated Drp1 oligomerization on endoplasmic reticulum

(2017) Wei-Ke Ji et al.   JOURNAL OF CELL BIOLOGY

ER-mitochondria tethering by PDZD8 regulates Ca2+dynamics in mammalian neurons

(2017) Yusuke Hirabayashi et al.   SCIENCE

Constriction of the mitochondrial inner compartment is a priming event for mitochondrial division

(2017) Bongki Cho et al.   Nature Communications

Mitofusin-2 knockdown increases ER-mitochondria contact and decreases amyloid β-peptide production

(2016) Nuno Santos Leal et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether

(2016) Deborah Naon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling

(2015) Riccardo Filadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division

(2015) Uri Manor et al.   eLife

A Role for Myosin II in Mammalian Mitochondrial Fission

(2014) Farida Korobova et al.   CURRENT BIOLOGY

Transient Contraction of Mitochondria Induces Depolarization through the Inner Membrane Dynamin OPA1 Protein

(2014) Hakjoo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -Synuclein Is Localized to Mitochondria-Associated ER Membranes

(2014) C. Guardia-Laguarta et al.   JOURNAL OF NEUROSCIENCE

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

(2013) F. Korobova et al.   SCIENCE

Parkinson’s disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

(2012) Xinglong Wang et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial Fission, Fusion, and Stress

(2012) R. J. Youle et al.   SCIENCE

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

(2011) Kurt J. De Vos et al.   HUMAN MOLECULAR GENETICS

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction

(2010) Ryota Iwasawa et al.   EMBO JOURNAL

ER sliding dynamics and ER–mitochondrial contacts occur on acetylated microtubules

(2010) Jonathan R. Friedman et al.   JOURNAL OF CELL BIOLOGY

Drosophila Porin/VDAC Affects Mitochondrial Morphology

(2010) Jeehye Park et al.   PLoS One

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE